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Items: 1 to 20 of 33


DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina.

Zullo JM, Demarco IA, Piqué-Regi R, Gaffney DJ, Epstein CB, Spooner CJ, Luperchio TR, Bernstein BE, Pritchard JK, Reddy KL, Singh H.

Cell. 2012 Jun 22;149(7):1474-87. doi: 10.1016/j.cell.2012.04.035.


Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase.

Errington WJ, Khan MQ, Bueler SA, Rubinstein JL, Chakrabartty A, Privé GG.

Structure. 2012 Jul 3;20(7):1141-53. doi: 10.1016/j.str.2012.04.009.


BAZF, a novel component of cullin3-based E3 ligase complex, mediates VEGFR and Notch cross-signaling in angiogenesis.

Ohnuki H, Inoue H, Takemori N, Nakayama H, Sakaue T, Fukuda S, Miwa D, Nishiwaki E, Hatano M, Tokuhisa T, Endo Y, Nose M, Higashiyama S.

Blood. 2012 Mar 15;119(11):2688-98. doi: 10.1182/blood-2011-03-345306.


Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection.

Bosch-Presegué L, Raurell-Vila H, Marazuela-Duque A, Kane-Goldsmith N, Valle A, Oliver J, Serrano L, Vaquero A.

Mol Cell. 2011 Apr 22;42(2):210-23. doi: 10.1016/j.molcel.2011.02.034.


Promyelocytic leukemia zinc finger turns on the effector T cell program without requirement for agonist TCR signaling.

Savage AK, Constantinides MG, Bendelac A.

J Immunol. 2011 May 15;186(10):5801-6. doi: 10.4049/jimmunol.1100119.


ATP-dependent chromatin remodeling: genetics, genomics and mechanisms.

Hargreaves DC, Crabtree GR.

Cell Res. 2011 Mar;21(3):396-420. doi: 10.1038/cr.2011.32. Review.


Follicular helper CD4 T cells (TFH).

Crotty S.

Annu Rev Immunol. 2011;29:621-63. doi: 10.1146/annurev-immunol-031210-101400. Review.


Silencing chromatin: comparing modes and mechanisms.

Beisel C, Paro R.

Nat Rev Genet. 2011 Feb;12(2):123-35. doi: 10.1038/nrg2932. Review.


The Cul4-Ddb1(Cdt)² ubiquitin ligase inhibits invasion of a boundary-associated antisilencing factor into heterochromatin.

Braun S, Garcia JF, Rowley M, Rougemaille M, Shankar S, Madhani HD.

Cell. 2011 Jan 7;144(1):41-54. doi: 10.1016/j.cell.2010.11.051.


DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination.

Du Z, Song J, Wang Y, Zhao Y, Guda K, Yang S, Kao HY, Xu Y, Willis J, Markowitz SD, Sedwick D, Ewing RM, Wang Z.

Sci Signal. 2010 Nov 2;3(146):ra80. doi: 10.1126/scisignal.2001462.


Structural assembly of cullin-RING ubiquitin ligase complexes.

Zimmerman ES, Schulman BA, Zheng N.

Curr Opin Struct Biol. 2010 Dec;20(6):714-21. doi: 10.1016/ Review.


BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis.

Basso K, Dalla-Favera R.

Adv Immunol. 2010;105:193-210. doi: 10.1016/S0065-2776(10)05007-8. Review.


Defining the human deubiquitinating enzyme interaction landscape.

Sowa ME, Bennett EJ, Gygi SP, Harper JW.

Cell. 2009 Jul 23;138(2):389-403. doi: 10.1016/j.cell.2009.04.042.


The transcription factor PLZF directs the effector program of the NKT cell lineage.

Savage AK, Constantinides MG, Han J, Picard D, Martin E, Li B, Lantz O, Bendelac A.

Immunity. 2008 Sep 19;29(3):391-403. doi: 10.1016/j.immuni.2008.07.011.


The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions.

Kovalovsky D, Uche OU, Eladad S, Hobbs RM, Yi W, Alonzo E, Chua K, Eidson M, Kim HJ, Im JS, Pandolfi PP, Sant'Angelo DB.

Nat Immunol. 2008 Sep;9(9):1055-64. doi: 10.1038/ni.1641.


Transcriptional repression mediated by repositioning of genes to the nuclear lamina.

Reddy KL, Zullo JM, Bertolino E, Singh H.

Nature. 2008 Mar 13;452(7184):243-7. doi: 10.1038/nature06727.


RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia.

Guidez F, Parks S, Wong H, Jovanovic JV, Mays A, Gilkes AF, Mills KI, Guillemin MC, Hobbs RM, Pandolfi PP, de Thé H, Solomon E, Grimwade D.

Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18694-9.


Constitutive turnover of cyclin E by Cul3 maintains quiescence.

McEvoy JD, Kossatz U, Malek N, Singer JD.

Mol Cell Biol. 2007 May;27(10):3651-66.


The PLZF gene of t (11;17)-associated APL.

McConnell MJ, Licht JD.

Curr Top Microbiol Immunol. 2007;313:31-48. Review.


The Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimer.

Wimuttisuk W, Singer JD.

Mol Biol Cell. 2007 Mar;18(3):899-909.

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