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Items: 1 to 20 of 27

1.

The cellular and signaling networks linking the immune system and metabolism in disease.

Osborn O, Olefsky JM.

Nat Med. 2012 Mar 6;18(3):363-74. doi: 10.1038/nm.2627. Review.

PMID:
22395709
2.
3.

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects.

Oh DY, Talukdar S, Bae EJ, Imamura T, Morinaga H, Fan W, Li P, Lu WJ, Watkins SM, Olefsky JM.

Cell. 2010 Sep 3;142(5):687-98. doi: 10.1016/j.cell.2010.07.041.

4.

Macrophage alpha1 AMP-activated protein kinase (alpha1AMPK) antagonizes fatty acid-induced inflammation through SIRT1.

Yang Z, Kahn BB, Shi H, Xue BZ.

J Biol Chem. 2010 Jun 18;285(25):19051-9. doi: 10.1074/jbc.M110.123620. Epub 2010 Apr 26.

5.

JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity.

Solinas G, Vilcu C, Neels JG, Bandyopadhyay GK, Luo JL, Naugler W, Grivennikov S, Wynshaw-Boris A, Scadeng M, Olefsky JM, Karin M.

Cell Metab. 2007 Nov;6(5):386-97.

6.

Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects.

Itoh M, Suganami T, Satoh N, Tanimoto-Koyama K, Yuan X, Tanaka M, Kawano H, Yano T, Aoe S, Takeya M, Shimatsu A, Kuzuya H, Kamei Y, Ogawa Y.

Arterioscler Thromb Vasc Biol. 2007 Sep;27(9):1918-25. Epub 2007 Jun 14.

7.

Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones.

Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, Watt MJ, Benner C, Febbraio MA, Nguyen AK, Folian B, Subramaniam S, Gonzalez FJ, Glass CK, Ricote M.

J Clin Invest. 2007 Jun;117(6):1658-69. Epub 2007 May 24.

8.

Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance.

Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, Mukundan L, Red Eagle A, Vats D, Brombacher F, Ferrante AW, Chawla A.

Nature. 2007 Jun 28;447(7148):1116-20. Epub 2007 May 21.

9.

TLR4 links innate immunity and fatty acid-induced insulin resistance.

Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS.

J Clin Invest. 2006 Nov;116(11):3015-25. Epub 2006 Oct 19.

10.

Comment on: White PJ, Marette A (2006) is omega-3 key to unlocking inflammation in obesity? Diabetologia 49:1999-2001.

Cereda E, Malavazos AE.

Diabetologia. 2006 Nov;49(11):2813-4. Epub 2006 Sep 19. No abstract available.

PMID:
17047915
11.

Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice.

Zang M, Xu S, Maitland-Toolan KA, Zuccollo A, Hou X, Jiang B, Wierzbicki M, Verbeuren TJ, Cohen RA.

Diabetes. 2006 Aug;55(8):2180-91.

12.

n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases.

Calder PC.

Am J Clin Nutr. 2006 Jun;83(6 Suppl):1505S-1519S. Review.

13.

Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids.

Todoric J, Löffler M, Huber J, Bilban M, Reimers M, Kadl A, Zeyda M, Waldhäusl W, Stulnig TM.

Diabetologia. 2006 Sep;49(9):2109-19. Epub 2006 Jun 17.

PMID:
16783472
14.

IKK-beta links inflammation to obesity-induced insulin resistance.

Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M.

Nat Med. 2005 Feb;11(2):191-8. Epub 2005 Jan 30.

PMID:
15685170
15.

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW.

EMBO J. 2004 Jun 16;23(12):2369-80. Epub 2004 May 20.

16.
17.

Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo.

Saha AK, Avilucea PR, Ye JM, Assifi MM, Kraegen EW, Ruderman NB.

Biochem Biophys Res Commun. 2004 Feb 6;314(2):580-5.

PMID:
14733947
18.

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance.

Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H.

J Clin Invest. 2003 Dec;112(12):1821-30.

19.

Obesity is associated with macrophage accumulation in adipose tissue.

Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr.

J Clin Invest. 2003 Dec;112(12):1796-808.

20.

n-3 Polyunsaturated fatty acids, inflammation and obesity-related disease.

Browning LM.

Proc Nutr Soc. 2003 May;62(2):447-53. Review.

PMID:
14506893

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