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Items: 1 to 20 of 25


Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths.

Zauber AG, Winawer SJ, O'Brien MJ, Lansdorp-Vogelaar I, van Ballegooijen M, Hankey BF, Shi W, Bond JH, Schapiro M, Panish JF, Stewart ET, Waye JD.

N Engl J Med. 2012 Feb 23;366(8):687-96. doi: 10.1056/NEJMoa1100370.


Exogenous Molecular Probes for Targeted Imaging in Cancer: Focus on Multi-modal Imaging.

Joshi BP, Wang TD.

Cancers (Basel). 2010 Jun 11;2(2):1251-87. doi: 10.3390/cancers2021251.


In vivo fluorescence-based endoscopic detection of colon dysplasia in the mouse using a novel peptide probe.

Miller SJ, Joshi BP, Feng Y, Gaustad A, Fearon ER, Wang TD.

PLoS One. 2011 Mar 8;6(3):e17384. doi: 10.1371/journal.pone.0017384.


Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.

Hung KE, Maricevich MA, Richard LG, Chen WY, Richardson MP, Kunin A, Bronson RT, Mahmood U, Kucherlapati R.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1565-70. doi: 10.1073/pnas.0908682107. Epub 2010 Jan 4.


Rapamycin inhibits oncogenic intestinal ion channels and neoplasia in APC(Min/+) mice.

Koehl GE, Spitzner M, Ousingsawat J, Schreiber R, Geissler EK, Kunzelmann K.

Oncogene. 2010 Mar 11;29(10):1553-60. doi: 10.1038/onc.2009.435. Epub 2009 Dec 7.


Longitudinal assessment of colonic tumor fate in mice by computed tomography and optical colonoscopy.

Durkee BY, Shinki K, Newton MA, Iverson CE, Weichert JP, Dove WF, Halberg RB.

Acad Radiol. 2009 Dec;16(12):1475-82. doi: 10.1016/j.acra.2009.07.023.


Endoscopic imaging and size estimation of colorectal adenomas in the multiple intestinal neoplasia mouse.

Hensley HH, Merkel CE, Chang WC, Devarajan K, Cooper HS, Clapper ML.

Gastrointest Endosc. 2009 Mar;69(3 Pt 2):742-9. doi: 10.1016/j.gie.2008.09.054.


Monitoring of tumor promotion and progression in a mouse model of inflammation-induced colon cancer with magnetic resonance colonography.

Young MR, Ileva LV, Bernardo M, Riffle LA, Jones YL, Kim YS, Colburn NH, Choyke PL.

Neoplasia. 2009 Mar;11(3):237-46, 1p following 246.


The role of mTOR in the management of solid tumors: an overview.

Strimpakos AS, Karapanagiotou EM, Saif MW, Syrigos KN.

Cancer Treat Rev. 2009 Apr;35(2):148-59. doi: 10.1016/j.ctrv.2008.09.006. Epub 2008 Nov 14. Review.


Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice.

Fujishita T, Aoki K, Lane HA, Aoki M, Taketo MM.

Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13544-9. doi: 10.1073/pnas.0800041105. Epub 2008 Sep 3.


Functional colonography of Min mice using dark lumen dynamic contrast-enhanced MRI.

Quarles CC, Lepage M, Gorden DL, Fingleton B, Yankeelov TE, Price RR, Matrisian LM, Gore JC, McIntyre JO.

Magn Reson Med. 2008 Sep;60(3):718-26. doi: 10.1002/mrm.21724.


Apc mice: models, modifiers and mutants.

McCart AE, Vickaryous NK, Silver A.

Pathol Res Pract. 2008;204(7):479-90. doi: 10.1016/j.prp.2008.03.004. Epub 2008 Jun 5. Review.


Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation.

Hinoi T, Akyol A, Theisen BK, Ferguson DO, Greenson JK, Williams BO, Cho KR, Fearon ER.

Cancer Res. 2007 Oct 15;67(20):9721-30.


High resolution colonoscopy in live mice.

Becker C, Fantini MC, Neurath MF.

Nat Protoc. 2006;1(6):2900-4.


Drosophila split ends homologue SHARP functions as a positive regulator of Wnt/beta-catenin/T-cell factor signaling in neoplastic transformation.

Feng Y, Bommer GT, Zhai Y, Akyol A, Hinoi T, Winer I, Lin HV, Cadigan KM, Cho KR, Fearon ER.

Cancer Res. 2007 Jan 15;67(2):482-91.


The use of targeted mouse models for preclinical testing of novel cancer therapeutics.

Olive KP, Tuveson DA.

Clin Cancer Res. 2006 Sep 15;12(18):5277-87. Review.


SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.

Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B.

Cell. 2006 Oct 6;127(1):125-37. Epub 2006 Sep 7.


TOR signaling in growth and metabolism.

Wullschleger S, Loewith R, Hall MN.

Cell. 2006 Feb 10;124(3):471-84. Review.


Molecular pathogenesis of colorectal cancer: implications for molecular diagnosis.

Arnold CN, Goel A, Blum HE, Boland CR.

Cancer. 2005 Nov 15;104(10):2035-47.


Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

Sarbassov DD, Guertin DA, Ali SM, Sabatini DM.

Science. 2005 Feb 18;307(5712):1098-101.

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