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Items: 1 to 20 of 49

1.

A-kinase anchoring proteins: scaffolding proteins in the heart.

Diviani D, Dodge-Kafka KL, Li J, Kapiloff MS.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1742-53. doi: 10.1152/ajpheart.00569.2011. Epub 2011 Aug 19. Review.

2.

Cell-type specific expression of a dominant negative PKA mutation in mice.

Willis BS, Niswender CM, Su T, Amieux PS, McKnight GS.

PLoS One. 2011 Apr 12;6(4):e18772. doi: 10.1371/journal.pone.0018772.

3.

Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons.

Marshall MR, Clark JP 3rd, Westenbroek R, Yu FH, Scheuer T, Catterall WA.

J Biol Chem. 2011 Apr 8;286(14):12627-39. doi: 10.1074/jbc.M110.175257. Epub 2011 Jan 11.

4.

Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes.

Christian F, Szaszák M, Friedl S, Drewianka S, Lorenz D, Goncalves A, Furkert J, Vargas C, Schmieder P, Götz F, Zühlke K, Moutty M, Göttert H, Joshi M, Reif B, Haase H, Morano I, Grossmann S, Klukovits A, Verli J, Gáspár R, Noack C, Bergmann M, Kass R, Hampel K, Kashin D, Genieser HG, Herberg FW, Willoughby D, Cooper DM, Baillie GS, Houslay MD, von Kries JP, Zimmermann B, Rosenthal W, Klussmann E.

J Biol Chem. 2011 Mar 18;286(11):9079-96. doi: 10.1074/jbc.M110.160614. Epub 2010 Dec 22.

5.

The large isoforms of A-kinase anchoring protein 18 mediate the phosphorylation of inhibitor-1 by protein kinase A and the inhibition of protein phosphatase 1 activity.

Singh A, Redden JM, Kapiloff MS, Dodge-Kafka KL.

Mol Pharmacol. 2011 Mar;79(3):533-40. doi: 10.1124/mol.110.065425. Epub 2010 Dec 13.

6.

Molecular mechanism of calcium channel regulation in the fight-or-flight response.

Fuller MD, Emrick MA, Sadilek M, Scheuer T, Catterall WA.

Sci Signal. 2010 Sep 28;3(141):ra70. doi: 10.1126/scisignal.2001152.

7.

Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels.

Nichols CB, Rossow CF, Navedo MF, Westenbroek RE, Catterall WA, Santana LF, McKnight GS.

Circ Res. 2010 Sep 17;107(6):747-56. doi: 10.1161/CIRCRESAHA.109.216127. Epub 2010 Jul 29.

8.

Disruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac function.

Patel HH, Hamuro LL, Chun BJ, Kawaraguchi Y, Quick A, Rebolledo B, Pennypacker J, Thurston J, Rodriguez-Pinto N, Self C, Olson G, Insel PA, Giles WR, Taylor SS, Roth DM.

J Biol Chem. 2010 Sep 3;285(36):27632-40. doi: 10.1074/jbc.M110.146589. Epub 2010 Jun 26.

9.

Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice.

Weisenhaus M, Allen ML, Yang L, Lu Y, Nichols CB, Su T, Hell JW, McKnight GS.

PLoS One. 2010 Apr 23;5(4):e10325. doi: 10.1371/journal.pone.0010325.

10.

Cooperative regulation of Ca(v)1.2 channels by intracellular Mg(2+), the proximal C-terminal EF-hand, and the distal C-terminal domain.

Brunet S, Scheuer T, Catterall WA.

J Gen Physiol. 2009 Aug;134(2):81-94. doi: 10.1085/jgp.200910209. Epub 2009 Jul 13.

11.

Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology.

Nicolaou P, Hajjar RJ, Kranias EG.

J Mol Cell Cardiol. 2009 Sep;47(3):365-71. doi: 10.1016/j.yjmcc.2009.05.010. Epub 2009 May 27. Review.

12.

AKAP-scaffolding proteins and regulation of cardiac physiology.

Mauban JR, O'Donnell M, Warrier S, Manni S, Bond M.

Physiology (Bethesda). 2009 Apr;24:78-87. doi: 10.1152/physiol.00041.2008. Review.

13.

A-kinase anchoring proteins: from protein complexes to physiology and disease.

Carnegie GK, Means CK, Scott JD.

IUBMB Life. 2009 Apr;61(4):394-406. doi: 10.1002/iub.168. Review.

14.

AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway.

Carnegie GK, Soughayer J, Smith FD, Pedroja BS, Zhang F, Diviani D, Bristow MR, Kunkel MT, Newton AC, Langeberg LK, Scott JD.

Mol Cell. 2008 Oct 24;32(2):169-79. doi: 10.1016/j.molcel.2008.08.030.

15.

Disruption of protein kinase A interaction with A-kinase-anchoring proteins in the heart in vivo: effects on cardiac contractility, protein kinase A phosphorylation, and troponin I proteolysis.

McConnell BK, Popovic Z, Mal N, Lee K, Bautista J, Forudi F, Schwartzman R, Jin JP, Penn M, Bond M.

J Biol Chem. 2009 Jan 16;284(3):1583-92. doi: 10.1074/jbc.M806321200. Epub 2008 Oct 21.

16.

Unchanged beta-adrenergic stimulation of cardiac L-type calcium channels in Ca v 1.2 phosphorylation site S1928A mutant mice.

Lemke T, Welling A, Christel CJ, Blaich A, Bernhard D, Lenhardt P, Hofmann F, Moosmang S.

J Biol Chem. 2008 Dec 12;283(50):34738-44. doi: 10.1074/jbc.M804981200. Epub 2008 Sep 30.

17.

The potential use of AKAP18delta as a drug target in heart failure patients.

Lygren B, Taskén K.

Expert Opin Biol Ther. 2008 Aug;8(8):1099-108. doi: 10.1517/14712598.8.8.1099 . Review.

PMID:
18613762
18.

AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension.

Navedo MF, Nieves-Cintrón M, Amberg GC, Yuan C, Votaw VS, Lederer WJ, McKnight GS, Santana LF.

Circ Res. 2008 Feb 1;102(2):e1-e11. doi: 10.1161/CIRCRESAHA.107.167809. Epub 2008 Jan 3.

19.

Mutation of an A-kinase-anchoring protein causes long-QT syndrome.

Chen L, Marquardt ML, Tester DJ, Sampson KJ, Ackerman MJ, Kass RS.

Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20990-5. Epub 2007 Dec 19.

20.

AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum.

Lygren B, Carlson CR, Santamaria K, Lissandron V, McSorley T, Litzenberg J, Lorenz D, Wiesner B, Rosenthal W, Zaccolo M, Taskén K, Klussmann E.

EMBO Rep. 2007 Nov;8(11):1061-7. Epub 2007 Sep 28.

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