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Adherence to antiretroviral therapy and acceptability of planned treatment interruptions in HIV-infected children.

Harrison L, Ananworanich J, Hamadache D, Compagnucci A, Penazzato M, Bunupuradah T, Mazza A, Ramos JT, Flynn J, Rampon O, Mellado Pena MJ, Floret D, Marczynska M, Puga A, Forcat S, Riault Y, Lallemant M, Castro H, Gibb DM, Giaquinto C; Paediatric European Network for Treatment of AIDS (PENTA) 11 Trial Team..

AIDS Behav. 2013 Jan;17(1):193-202. doi: 10.1007/s10461-012-0197-y.


A meta-analysis of adherence to antiretroviral therapy and virologic responses in HIV-infected children, adolescents, and young adults.

Kahana SY, Rohan J, Allison S, Frazier TW, Drotar D.

AIDS Behav. 2013 Jan;17(1):41-60. doi: 10.1007/s10461-012-0159-4. Review.


Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization.

Baitsch L, Legat A, Barba L, Fuertes Marraco SA, Rivals JP, Baumgaertner P, Christiansen-Jucht C, Bouzourene H, Rimoldi D, Pircher H, Rufer N, Matter M, Michielin O, Speiser DE.

PLoS One. 2012;7(2):e30852. doi: 10.1371/journal.pone.0030852. Epub 2012 Feb 8.


Approaches towards avoiding lifelong antiretroviral therapy in paediatric HIV infection.

Goulder PJ, Prendergast AJ.

Adv Exp Med Biol. 2011;719:25-37. doi: 10.1007/978-1-4614-0204-6_3. Review. No abstract available.


Further evidence that the expression of CD38 and HLA-DR(+) in CD8(+) lymphocytes does not correlate to disease progression in HIV-1 vertically infected children.

Romeiro JR, Pinto JA, Silva ML, Eloi-Santos SM.

J Int Assoc Physicians AIDS Care (Chic). 2012 May-Jun;11(3):164-8. doi: 10.1177/1545109711421642. Epub 2011 Oct 5.


Identification of human endogenous retrovirus-specific T cell responses in vertically HIV-1-infected subjects.

Tandon R, SenGupta D, Ndhlovu LC, Vieira RG, Jones RB, York VA, Vieira VA, Sharp ER, Wiznia AA, Ostrowski MA, Rosenberg MG, Nixon DF.

J Virol. 2011 Nov;85(21):11526-31. doi: 10.1128/JVI.05418-11. Epub 2011 Aug 31.


Factors influencing T cell activation and programmed death 1 expression in HIV-infected children.

Prendergast A, O'Callaghan M, Menson E, Hamadache D, Walters S, Klein N, Goulder P.

AIDS Res Hum Retroviruses. 2012 May;28(5):465-8. doi: 10.1089/AID.2011.0113. Epub 2011 Sep 7.


Phosphotyrosine-dependent coupling of Tim-3 to T-cell receptor signaling pathways.

Lee J, Su EW, Zhu C, Hainline S, Phuah J, Moroco JA, Smithgall TE, Kuchroo VK, Kane LP.

Mol Cell Biol. 2011 Oct;31(19):3963-74. doi: 10.1128/MCB.05297-11. Epub 2011 Aug 1.


Are senescence and exhaustion intertwined or unrelated processes that compromise immunity?

Akbar AN, Henson SM.

Nat Rev Immunol. 2011 Apr;11(4):289-95. doi: 10.1038/nri2959. Review.


Suppression of HIV replication by antiretroviral therapy reduces TIM-3 expression on HIV-specific CD8(+) T cells.

Kassu A, Marcus RA, D'Souza MB, Kelly-McKnight EA, Palmer BE.

AIDS Res Hum Retroviruses. 2011 Jan;27(1):1-3. doi: 10.1089/aid.2010.0156. Epub 2010 Sep 23. No abstract available.


Serious fatal and nonfatal non-AIDS-defining illnesses in Europe.

Mocroft A, Reiss P, Gasiorowski J, Ledergerber B, Kowalska J, Chiesi A, Gatell J, Rakhmanova A, Johnson M, Kirk O, Lundgren J; EuroSIDA Study Group..

J Acquir Immune Defic Syndr. 2010 Oct;55(2):262-70. doi: 10.1097/QAI.0b013e3181e9be6b.


Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

Jin HT, Anderson AC, Tan WG, West EE, Ha SJ, Araki K, Freeman GJ, Kuchroo VK, Ahmed R.

Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14733-8. doi: 10.1073/pnas.1009731107. Epub 2010 Aug 2.


Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation.

Bengsch B, Seigel B, Ruhl M, Timm J, Kuntz M, Blum HE, Pircher H, Thimme R.

PLoS Pathog. 2010 Jun 10;6(6):e1000947. doi: 10.1371/journal.ppat.1000947.


Early immune senescence in HIV disease.

Desai S, Landay A.

Curr HIV/AIDS Rep. 2010 Feb;7(1):4-10. doi: 10.1007/s11904-009-0038-4.


Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice.

Chou FC, Shieh SJ, Sytwu HK.

Eur J Immunol. 2009 Sep;39(9):2403-11. doi: 10.1002/eji.200839177.


Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells.

Golden-Mason L, Palmer BE, Kassam N, Townshend-Bulson L, Livingston S, McMahon BJ, Castelblanco N, Kuchroo V, Gretch DR, Rosen HR.

J Virol. 2009 Sep;83(18):9122-30. doi: 10.1128/JVI.00639-09. Epub 2009 Jul 8.


Age-associated up-regulation of a negative co-stimulatory receptor PD-1 in mouse CD4+ T cells.

Shimada Y, Hayashi M, Nagasaka Y, Ohno-Iwashita Y, Inomata M.

Exp Gerontol. 2009 Aug;44(8):517-22. doi: 10.1016/j.exger.2009.05.003. Epub 2009 May 18.


Prevention of infectious diseases in older adults through immunization: the challenge of the senescent immune response.

McElhaney JE.

Expert Rev Vaccines. 2009 May;8(5):593-606. doi: 10.1586/erv.09.12. Review.


High CD8+ T cell activation marks a less differentiated HIV-1 specific CD8+ T cell response that is not altered by suppression of viral replication.

Barbour JD, Ndhlovu LC, Xuan Tan Q, Ho T, Epling L, Bredt BM, Levy JA, Hecht FM, Sinclair E.

PLoS One. 2009;4(2):e4408. doi: 10.1371/journal.pone.0004408. Epub 2009 Feb 9.


Premature aging of T cells is associated with faster HIV-1 disease progression.

Cao W, Jamieson BD, Hultin LE, Hultin PM, Effros RB, Detels R.

J Acquir Immune Defic Syndr. 2009 Feb 1;50(2):137-47. doi: 10.1097/QAI.0b013e3181926c28.

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