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Items: 1 to 20 of 50

1.

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

Zielinski CE, Mele F, Aschenbrenner D, Jarrossay D, Ronchi F, Gattorno M, Monticelli S, Lanzavecchia A, Sallusto F.

Nature. 2012 Apr 26;484(7395):514-8. doi: 10.1038/nature10957.

PMID:
22466287
2.

Control of TH17 cells occurs in the small intestine.

Esplugues E, Huber S, Gagliani N, Hauser AE, Town T, Wan YY, O'Connor W Jr, Rongvaux A, Van Rooijen N, Haberman AM, Iwakura Y, Kuchroo VK, Kolls JK, Bluestone JA, Herold KC, Flavell RA.

Nature. 2011 Jul 17;475(7357):514-8. doi: 10.1038/nature10228.

3.

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

Codarri L, Gyülvészi G, Tosevski V, Hesske L, Fontana A, Magnenat L, Suter T, Becher B.

Nat Immunol. 2011 Jun;12(6):560-7. doi: 10.1038/ni.2027. Epub 2011 Apr 24.

PMID:
21516112
4.

The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.

El-Behi M, Ciric B, Dai H, Yan Y, Cullimore M, Safavi F, Zhang GX, Dittel BN, Rostami A.

Nat Immunol. 2011 Jun;12(6):568-75. doi: 10.1038/ni.2031. Epub 2011 Apr 24.

5.

Fate mapping of IL-17-producing T cells in inflammatory responses.

Hirota K, Duarte JH, Veldhoen M, Hornsby E, Li Y, Cua DJ, Ahlfors H, Wilhelm C, Tolaini M, Menzel U, Garefalaki A, Potocnik AJ, Stockinger B.

Nat Immunol. 2011 Mar;12(3):255-63. doi: 10.1038/ni.1993. Epub 2011 Jan 30.

6.

Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling.

Ghoreschi K, Laurence A, Yang XP, Tato CM, McGeachy MJ, Konkel JE, Ramos HL, Wei L, Davidson TS, Bouladoux N, Grainger JR, Chen Q, Kanno Y, Watford WT, Sun HW, Eberl G, Shevach EM, Belkaid Y, Cua DJ, Chen W, O'Shea JJ.

Nature. 2010 Oct 21;467(7318):967-71. doi: 10.1038/nature09447.

7.

IL-7Rα confers susceptibility to experimental autoimmune encephalomyelitis.

Walline CC, Kanakasabai S, Bright JJ.

Genes Immun. 2011 Jan;12(1):1-14. doi: 10.1038/gene.2010.49. Epub 2010 Sep 23.

8.

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27.

Apetoh L, Quintana FJ, Pot C, Joller N, Xiao S, Kumar D, Burns EJ, Sherr DH, Weiner HL, Kuchroo VK.

Nat Immunol. 2010 Sep;11(9):854-61. doi: 10.1038/ni.1912. Epub 2010 Aug 1.

9.

Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease.

Liu X, Leung S, Wang C, Tan Z, Wang J, Guo TB, Fang L, Zhao Y, Wan B, Qin X, Lu L, Li R, Pan H, Song M, Liu A, Hong J, Lu H, Zhang JZ.

Nat Med. 2010 Feb;16(2):191-7. doi: 10.1038/nm.2077. Epub 2010 Jan 10. Retraction in: Nat Med. 2013 Dec;19(12):1673.

PMID:
20062065
10.

Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes.

Jäger A, Dardalhon V, Sobel RA, Bettelli E, Kuchroo VK.

J Immunol. 2009 Dec 1;183(11):7169-77. doi: 10.4049/jimmunol.0901906. Epub 2009 Nov 4.

11.

T-bet is essential for encephalitogenicity of both Th1 and Th17 cells.

Yang Y, Weiner J, Liu Y, Smith AJ, Huss DJ, Winger R, Peng H, Cravens PD, Racke MK, Lovett-Racke AE.

J Exp Med. 2009 Jul 6;206(7):1549-64. doi: 10.1084/jem.20082584. Epub 2009 Jun 22.

12.

Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells.

Awasthi A, Riol-Blanco L, Jäger A, Korn T, Pot C, Galileos G, Bettelli E, Kuchroo VK, Oukka M.

J Immunol. 2009 May 15;182(10):5904-8. doi: 10.4049/jimmunol.0900732.

13.

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo.

McGeachy MJ, Chen Y, Tato CM, Laurence A, Joyce-Shaikh B, Blumenschein WM, McClanahan TK, O'Shea JJ, Cua DJ.

Nat Immunol. 2009 Mar;10(3):314-24. doi: 10.1038/ni.1698. Epub 2009 Feb 1.

14.

IL-17 and Th17 Cells.

Korn T, Bettelli E, Oukka M, Kuchroo VK.

Annu Rev Immunol. 2009;27:485-517. doi: 10.1146/annurev.immunol.021908.132710. Review.

PMID:
19132915
15.

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells.

Bauquet AT, Jin H, Paterson AM, Mitsdoerffer M, Ho IC, Sharpe AH, Kuchroo VK.

Nat Immunol. 2009 Feb;10(2):167-75. doi: 10.1038/ni.1690. Epub 2008 Dec 21.

16.

Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis.

O'Connor RA, Prendergast CT, Sabatos CA, Lau CW, Leech MD, Wraith DC, Anderton SM.

J Immunol. 2008 Sep 15;181(6):3750-4.

17.

Induction and effector functions of T(H)17 cells.

Bettelli E, Korn T, Oukka M, Kuchroo VK.

Nature. 2008 Jun 19;453(7198):1051-7. doi: 10.1038/nature07036. Review.

PMID:
18563156
18.

Association of interleukin-23 receptor variants with ankylosing spondylitis.

Rahman P, Inman RD, Gladman DD, Reeve JP, Peddle L, Maksymowych WP.

Arthritis Rheum. 2008 Apr;58(4):1020-5. doi: 10.1002/art.23389.

19.

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor.

Quintana FJ, Basso AS, Iglesias AH, Korn T, Farez MF, Bettelli E, Caccamo M, Oukka M, Weiner HL.

Nature. 2008 May 1;453(7191):65-71. doi: 10.1038/nature06880. Epub 2008 Mar 23.

PMID:
18362915
20.

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins.

Veldhoen M, Hirota K, Westendorf AM, Buer J, Dumoutier L, Renauld JC, Stockinger B.

Nature. 2008 May 1;453(7191):106-9. doi: 10.1038/nature06881. Epub 2008 Mar 23.

PMID:
18362914

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