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Items: 1 to 20 of 51

1.

Pioneer transcription factors: establishing competence for gene expression.

Zaret KS, Carroll JS.

Genes Dev. 2011 Nov 1;25(21):2227-41. doi: 10.1101/gad.176826.111. Review.

2.

Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration.

Trompouki E, Bowman TV, Lawton LN, Fan ZP, Wu DC, DiBiase A, Martin CS, Cech JN, Sessa AK, Leblanc JL, Li P, Durand EM, Mosimann C, Heffner GC, Daley GQ, Paulson RF, Young RA, Zon LI.

Cell. 2011 Oct 28;147(3):577-89. doi: 10.1016/j.cell.2011.09.044.

3.

Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway.

Zhou Y, Zhang E, Berggreen C, Jing X, Osmark P, Lang S, Cilio CM, Göransson O, Groop L, Renström E, Hansson O.

Hum Mol Genet. 2012 Jan 1;21(1):196-207. doi: 10.1093/hmg/ddr454. Epub 2011 Sep 30.

PMID:
21965303
4.

Using ChIP-seq technology to generate high-resolution profiles of histone modifications.

O'Geen H, Echipare L, Farnham PJ.

Methods Mol Biol. 2011;791:265-86. doi: 10.1007/978-1-61779-316-5_20.

5.

An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes.

Locke JM, Da Silva Xavier G, Rutter GA, Harries LW.

Diabetologia. 2011 Dec;54(12):3078-82. doi: 10.1007/s00125-011-2290-6. Epub 2011 Sep 14. Erratum in: Diabetologia. 2011 Dec;54(12):3170.

6.

Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism.

Norton L, Fourcaudot M, Abdul-Ghani MA, Winnier D, Mehta FF, Jenkinson CP, Defronzo RA.

Diabetologia. 2011 Dec;54(12):3132-42. doi: 10.1007/s00125-011-2289-z. Epub 2011 Sep 7.

PMID:
21901280
7.

Wnt signaling meets internal dissent.

Grove EA.

Genes Dev. 2011 Sep 1;25(17):1759-62. doi: 10.1101/gad.17594311.

8.

Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors.

Sekiya S, Suzuki A.

Nature. 2011 Jun 29;475(7356):390-3. doi: 10.1038/nature10263.

PMID:
21716291
9.

At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia.

Hansen T, Ingason A, Djurovic S, Melle I, Fenger M, Gustafsson O, Jakobsen KD, Rasmussen HB, Tosato S, Rietschel M, Frank J, Owen M, Bonetto C, Suvisaari J, Thygesen JH, Pétursson H, Lönnqvist J, Sigurdsson E, Giegling I, Craddock N, O'Donovan MC, Ruggeri M, Cichon S, Ophoff RA, Pietiläinen O, Peltonen L, Nöthen MM, Rujescu D, St Clair D, Collier DA, Andreassen OA, Werge T.

Biol Psychiatry. 2011 Jul 1;70(1):59-63. doi: 10.1016/j.biopsych.2011.01.031. Epub 2011 Mar 16.

PMID:
21414605
10.

TCF7L2 splice variants have distinct effects on beta-cell turnover and function.

Le Bacquer O, Shu L, Marchand M, Neve B, Paroni F, Kerr Conte J, Pattou F, Froguel P, Maedler K.

Hum Mol Genet. 2011 May 15;20(10):1906-15. doi: 10.1093/hmg/ddr072. Epub 2011 Feb 28.

PMID:
21357677
11.

Characterization of the contradictory chromatin signatures at the 3' exons of zinc finger genes.

Blahnik KR, Dou L, Echipare L, Iyengar S, O'Geen H, Sanchez E, Zhao Y, Marra MA, Hirst M, Costello JF, Korf I, Farnham PJ.

PLoS One. 2011 Feb 15;6(2):e17121. doi: 10.1371/journal.pone.0017121.

12.

W-ChIPeaks: a comprehensive web application tool for processing ChIP-chip and ChIP-seq data.

Lan X, Bonneville R, Apostolos J, Wu W, Jin VX.

Bioinformatics. 2011 Feb 1;27(3):428-30. doi: 10.1093/bioinformatics/btq669. Epub 2010 Dec 7.

13.

Molecular function of TCF7L2: Consequences of TCF7L2 splicing for molecular function and risk for type 2 diabetes.

Hansson O, Zhou Y, Renström E, Osmark P.

Curr Diab Rep. 2010 Dec;10(6):444-51. doi: 10.1007/s11892-010-0149-8. Review.

PMID:
20878273
14.

TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.

Verzi MP, Hatzis P, Sulahian R, Philips J, Schuijers J, Shin H, Freed E, Lynch JP, Dang DT, Brown M, Clevers H, Liu XS, Shivdasani RA.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15157-62. doi: 10.1073/pnas.1003822107. Epub 2010 Aug 9.

15.

Using ChIP-seq technology to identify targets of zinc finger transcription factors.

O'Geen H, Frietze S, Farnham PJ.

Methods Mol Biol. 2010;649:437-55. doi: 10.1007/978-1-60761-753-2_27.

16.

GATA switches as developmental drivers.

Bresnick EH, Lee HY, Fujiwara T, Johnson KD, Keles S.

J Biol Chem. 2010 Oct 8;285(41):31087-93. doi: 10.1074/jbc.R110.159079. Epub 2010 Jul 29. Review.

17.

Disease-associated loci are significantly over-represented among genes bound by transcription factor 7-like 2 (TCF7L2) in vivo.

Zhao J, Schug J, Li M, Kaestner KH, Grant SF.

Diabetologia. 2010 Nov;53(11):2340-6. doi: 10.1007/s00125-010-1852-3. Epub 2010 Jul 17.

PMID:
20640398
18.

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.

Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Bengtsson Boström K, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL, Morris AD, Palmer CN, Pramstaller PP, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Wareham NJ, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Hu FB, Meigs JB, Pankow JS, Pedersen O, Wichmann HE, Barroso I, Florez JC, Frayling TM, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI; MAGIC investigators.; GIANT Consortium..

Nat Genet. 2010 Jul;42(7):579-89. doi: 10.1038/ng.609. Erratum in: Nat Genet. 2011 Apr;43(4):388.

19.

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver.

Hoffman BG, Robertson G, Zavaglia B, Beach M, Cullum R, Lee S, Soukhatcheva G, Li L, Wederell ED, Thiessen N, Bilenky M, Cezard T, Tam A, Kamoh B, Birol I, Dai D, Zhao Y, Hirst M, Verchere CB, Helgason CD, Marra MA, Jones SJ, Hoodless PA.

Genome Res. 2010 Aug;20(8):1037-51. doi: 10.1101/gr.104356.109. Epub 2010 Jun 15.

20.

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities.

Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK.

Mol Cell. 2010 May 28;38(4):576-89. doi: 10.1016/j.molcel.2010.05.004.

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