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Items: 1 to 20 of 50

1.

Toward stable genetic engineering of human O-glycosylation in plants.

Yang Z, Bennett EP, Jørgensen B, Drew DP, Arigi E, Mandel U, Ulvskov P, Levery SB, Clausen H, Petersen BL.

Plant Physiol. 2012 Sep;160(1):450-63. doi: 10.1104/pp.112.198200. Epub 2012 Jul 12.

2.

Determination of site-specific glycan heterogeneity on glycoproteins.

Kolarich D, Jensen PH, Altmann F, Packer NH.

Nat Protoc. 2012 Jun 7;7(7):1285-98. doi: 10.1038/nprot.2012.062.

PMID:
22678432
3.

IgG-Fc glycoengineering in non-mammalian expression hosts.

Loos A, Steinkellner H.

Arch Biochem Biophys. 2012 Oct 15;526(2):167-73. doi: 10.1016/j.abb.2012.05.011. Epub 2012 May 23. Review.

4.

Production platforms for biotherapeutic glycoproteins. Occurrence, impact, and challenges of non-human sialylation.

Ghaderi D, Zhang M, Hurtado-Ziola N, Varki A.

Biotechnol Genet Eng Rev. 2012;28:147-75. Review.

PMID:
22616486
5.

In vivo analysis of the role of O-glycosylations of von Willebrand factor.

Badirou I, Kurdi M, Legendre P, Rayes J, Bryckaert M, Casari C, Lenting PJ, Christophe OD, Denis CV.

PLoS One. 2012;7(5):e37508. doi: 10.1371/journal.pone.0037508. Epub 2012 May 17.

6.

Drug-making plant blooms.

Maxmen A.

Nature. 2012 May 8;485(7397):160. doi: 10.1038/485160a. No abstract available.

PMID:
22575938
7.

Isotype and glycoform selection for antibody therapeutics.

Jefferis R.

Arch Biochem Biophys. 2012 Oct 15;526(2):159-66. doi: 10.1016/j.abb.2012.03.021. Epub 2012 Mar 23. Review.

PMID:
22465822
8.

Biologically active, magnICON®-expressed EPO-Fc from stably transformed Nicotiana benthamiana plants presenting tetra-antennary N-glycan structures.

Nagels B, Van Damme EJ, Callewaert N, Zabeau L, Tavernier J, Delanghe JR, Boets A, Castilho A, Weterings K.

J Biotechnol. 2012 Aug 31;160(3-4):242-50. doi: 10.1016/j.jbiotec.2012.03.003. Epub 2012 Mar 16.

PMID:
22430811
9.

Engineering mammalian mucin-type O-glycosylation in plants.

Yang Z, Drew DP, Jørgensen B, Mandel U, Bach SS, Ulvskov P, Levery SB, Bennett EP, Clausen H, Petersen BL.

J Biol Chem. 2012 Apr 6;287(15):11911-23. doi: 10.1074/jbc.M111.312918. Epub 2012 Feb 14.

10.

Growth, productivity and protein glycosylation in a CHO EpoFc producer cell line adapted to glutamine-free growth.

Taschwer M, Hackl M, Hernández Bort JA, Leitner C, Kumar N, Puc U, Grass J, Papst M, Kunert R, Altmann F, Borth N.

J Biotechnol. 2012 Jan 20;157(2):295-303. doi: 10.1016/j.jbiotec.2011.11.014. Epub 2011 Dec 9.

PMID:
22178781
11.

Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines.

Steentoft C, Vakhrushev SY, Vester-Christensen MB, Schjoldager KT, Kong Y, Bennett EP, Mandel U, Wandall H, Levery SB, Clausen H.

Nat Methods. 2011 Oct 9;8(11):977-82. doi: 10.1038/nmeth.1731.

PMID:
21983924
12.

Pivotal trial with plant cell-expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease.

Zimran A, Brill-Almon E, Chertkoff R, Petakov M, Blanco-Favela F, Muñoz ET, Solorio-Meza SE, Amato D, Duran G, Giona F, Heitner R, Rosenbaum H, Giraldo P, Mehta A, Park G, Phillips M, Elstein D, Altarescu G, Szleifer M, Hashmueli S, Aviezer D.

Blood. 2011 Nov 24;118(22):5767-73. doi: 10.1182/blood-2011-07-366955. Epub 2011 Sep 6. Erratum in: Blood. 2012 May 10;119(19):4577.

13.

Recombinant plant-expressed tumour-associated MUC1 peptide is immunogenic and capable of breaking tolerance in MUC1.Tg mice.

Pinkhasov J, Alvarez ML, Rigano MM, Piensook K, Larios D, Pabst M, Grass J, Mukherjee P, Gendler SJ, Walmsley AM, Mason HS.

Plant Biotechnol J. 2011 Dec;9(9):991-1001. doi: 10.1111/j.1467-7652.2011.00614.x. Epub 2011 Jul 11.

14.

O-glycosylated cell wall proteins are essential in root hair growth.

Velasquez SM, Ricardi MM, Dorosz JG, Fernandez PV, Nadra AD, Pol-Fachin L, Egelund J, Gille S, Harholt J, Ciancia M, Verli H, Pauly M, Bacic A, Olsen CE, Ulvskov P, Petersen BL, Somerville C, Iusem ND, Estevez JM.

Science. 2011 Jun 17;332(6036):1401-3. doi: 10.1126/science.1206657.

15.

Reduction of plant-specific arabinogalactan-type O-glycosylation by treating tobacco plants with ferrous chelator 2,2'-dipyridyl.

Moriguchi R, Matsuoka C, Suyama A, Matsuoka K.

Biosci Biotechnol Biochem. 2011;75(5):994-6. Epub 2011 May 20.

16.

Enhanced sialylation of recombinant human erythropoietin in Chinese hamster ovary cells by combinatorial engineering of selected genes.

Son YD, Jeong YT, Park SY, Kim JH.

Glycobiology. 2011 Aug;21(8):1019-28. doi: 10.1093/glycob/cwr034. Epub 2011 Mar 24.

PMID:
21436238
17.

N-glycosylation engineering of plants for the biosynthesis of glycoproteins with bisected and branched complex N-glycans.

Castilho A, Gattinger P, Grass J, Jez J, Pabst M, Altmann F, Gorfer M, Strasser R, Steinkellner H.

Glycobiology. 2011 Jun;21(6):813-23. doi: 10.1093/glycob/cwr009. Epub 2011 Feb 11.

18.

The Tn antigen-structural simplicity and biological complexity.

Ju T, Otto VI, Cummings RD.

Angew Chem Int Ed Engl. 2011 Feb 18;50(8):1770-91. doi: 10.1002/anie.201002313. Epub 2011 Jan 21. Review.

PMID:
21259410
19.
20.

In planta protein sialylation through overexpression of the respective mammalian pathway.

Castilho A, Strasser R, Stadlmann J, Grass J, Jez J, Gattinger P, Kunert R, Quendler H, Pabst M, Leonard R, Altmann F, Steinkellner H.

J Biol Chem. 2010 May 21;285(21):15923-30. doi: 10.1074/jbc.M109.088401. Epub 2010 Mar 20.

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