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Items: 1 to 20 of 63

1.

Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia.

Bhatla T, Wang J, Morrison DJ, Raetz EA, Burke MJ, Brown P, Carroll WL.

Blood. 2012 May 31;119(22):5201-10. doi: 10.1182/blood-2012-01-401687. Epub 2012 Apr 11.

2.

Essential role for telomerase in chronic myeloid leukemia induced by BCR-ABL in mice.

Vicente-Dueñas C, Barajas-Diego M, Romero-Camarero I, González-Herrero I, Flores T, Sánchez-García I.

Oncotarget. 2012 Mar;3(3):261-6.

3.

The mixed lineage leukemia (MLL) fusion-associated gene AF4 promotes CD133 transcription.

Mak AB, Nixon AM, Moffat J.

Cancer Res. 2012 Apr 15;72(8):1929-34. doi: 10.1158/0008-5472.CAN-11-3589. Epub 2012 Feb 14.

4.

Global DNA demethylation during mouse erythropoiesis in vivo.

Shearstone JR, Pop R, Bock C, Boyle P, Meissner A, Socolovsky M.

Science. 2011 Nov 11;334(6057):799-802. doi: 10.1126/science.1207306.

5.

Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia.

Kikushige Y, Ishikawa F, Miyamoto T, Shima T, Urata S, Yoshimoto G, Mori Y, Iino T, Yamauchi T, Eto T, Niiro H, Iwasaki H, Takenaka K, Akashi K.

Cancer Cell. 2011 Aug 16;20(2):246-59. doi: 10.1016/j.ccr.2011.06.029.

6.

Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling.

Gu H, Smith ZD, Bock C, Boyle P, Gnirke A, Meissner A.

Nat Protoc. 2011 Apr;6(4):468-81. doi: 10.1038/nprot.2010.190. Epub 2011 Mar 18.

PMID:
21412275
7.

The progression from MGUS to smoldering myeloma and eventually to multiple myeloma involves a clonal expansion of genetically abnormal plasma cells.

López-Corral L, Gutiérrez NC, Vidriales MB, Mateos MV, Rasillo A, García-Sanz R, Paiva B, San Miguel JF.

Clin Cancer Res. 2011 Apr 1;17(7):1692-700. doi: 10.1158/1078-0432.CCR-10-1066. Epub 2011 Feb 16.

8.

Cells of origin in cancer.

Visvader JE.

Nature. 2011 Jan 20;469(7330):314-22. doi: 10.1038/nature09781. Review.

PMID:
21248838
9.

A novel transgenic mouse model of the human multiple myeloma chromosomal translocation t(14;16)(q32;q23).

Morito N, Yoh K, Maeda A, Nakano T, Fujita A, Kusakabe M, Hamada M, Kudo T, Yamagata K, Takahashi S.

Cancer Res. 2011 Jan 15;71(2):339-48. doi: 10.1158/0008-5472.CAN-10-1057. Epub 2011 Jan 11.

10.

Quantitative comparison of genome-wide DNA methylation mapping technologies.

Bock C, Tomazou EM, Brinkman AB, Müller F, Simmer F, Gu H, Jäger N, Gnirke A, Stunnenberg HG, Meissner A.

Nat Biotechnol. 2010 Oct;28(10):1106-14. doi: 10.1038/nbt.1681. Epub 2010 Sep 19.

11.

BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells.

Molyneux G, Geyer FC, Magnay FA, McCarthy A, Kendrick H, Natrajan R, Mackay A, Grigoriadis A, Tutt A, Ashworth A, Reis-Filho JS, Smalley MJ.

Cell Stem Cell. 2010 Sep 3;7(3):403-17. doi: 10.1016/j.stem.2010.07.010.

12.

Getting to the stem of cancer.

Sánchez-García I.

Semin Cancer Biol. 2010 Apr;20(2):63-4. doi: 10.1016/j.semcancer.2010.05.001. Epub 2010 May 6. No abstract available.

PMID:
20451615
13.

Cancer as a reprogramming-like disease: implications in tumor development and treatment.

Castellanos A, Vicente-Dueñas C, Campos-Sánchez E, Cruz JJ, García-Criado FJ, García-Cenador MB, Lazo PA, Pérez-Losada J, Sánchez-García I.

Semin Cancer Biol. 2010 Apr;20(2):93-7. doi: 10.1016/j.semcancer.2010.02.001. Epub 2010 Feb 24. Review.

PMID:
20188174
14.

Physiological cellular reprogramming and cancer.

Abollo-Jiménez F, Jiménez R, Cobaleda C.

Semin Cancer Biol. 2010 Apr;20(2):98-106. doi: 10.1016/j.semcancer.2010.02.002. Epub 2010 Feb 24. Review.

PMID:
20188173
15.

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers.

Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH, Asselin-Labat ML, Gyorki DE, Ward T, Partanen A, Feleppa F, Huschtscha LI, Thorne HJ; kConFab, Fox SB, Yan M, French JD, Brown MA, Smyth GK, Visvader JE, Lindeman GJ.

Nat Med. 2009 Aug;15(8):907-13. doi: 10.1038/nm.2000. Epub 2009 Aug 2.

PMID:
19648928
16.

MafB restricts M-CSF-dependent myeloid commitment divisions of hematopoietic stem cells.

Sarrazin S, Mossadegh-Keller N, Fukao T, Aziz A, Mourcin F, Vanhille L, Kelly Modis L, Kastner P, Chan S, Duprez E, Otto C, Sieweke MH.

Cell. 2009 Jul 23;138(2):300-13. doi: 10.1016/j.cell.2009.04.057.

17.

B-cell acute lymphoblastic leukaemia: towards understanding its cellular origin.

Cobaleda C, Sánchez-García I.

Bioessays. 2009 Jun;31(6):600-9. doi: 10.1002/bies.200800234. Review.

PMID:
19444834
18.

A functional screen to identify novel effectors of hematopoietic stem cell activity.

Deneault E, Cellot S, Faubert A, Laverdure JP, Fréchette M, Chagraoui J, Mayotte N, Sauvageau M, Ting SB, Sauvageau G.

Cell. 2009 Apr 17;137(2):369-79. doi: 10.1016/j.cell.2009.03.026.

19.

A new MAFia in cancer.

Eychène A, Rocques N, Pouponnot C.

Nat Rev Cancer. 2008 Sep;8(9):683-93. doi: 10.1038/nrc2460. Review.

PMID:
19143053
20.

Cancer induction by restriction of oncogene expression to the stem cell compartment.

Pérez-Caro M, Cobaleda C, González-Herrero I, Vicente-Dueñas C, Bermejo-Rodríguez C, Sánchez-Beato M, Orfao A, Pintado B, Flores T, Sánchez-Martín M, Jiménez R, Piris MA, Sánchez-García I.

EMBO J. 2009 Jan 7;28(1):8-20. doi: 10.1038/emboj.2008.253. Epub 2008 Nov 27.

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