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Items: 1 to 20 of 58

1.

Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation.

Mullican SE, Gaddis CA, Alenghat T, Nair MG, Giacomin PR, Everett LJ, Feng D, Steger DJ, Schug J, Artis D, Lazar MA.

Genes Dev. 2011 Dec 1;25(23):2480-8. doi: 10.1101/gad.175950.111.

2.

Metabolomics-lipidomics of eicosanoids and docosanoids generated by phagocytes.

Yang R, Chiang N, Oh SF, Serhan CN.

Curr Protoc Immunol. 2011 Nov;Chapter 14:Unit 14.26. doi: 10.1002/0471142735.im1426s95.

3.

Transcriptional regulation of macrophage polarization: enabling diversity with identity.

Lawrence T, Natoli G.

Nat Rev Immunol. 2011 Oct 25;11(11):750-61. doi: 10.1038/nri3088. Review.

PMID:
22025054
4.

Fish the ChIPs: a pipeline for automated genomic annotation of ChIP-Seq data.

Barozzi I, Termanini A, Minucci S, Natoli G.

Biol Direct. 2011 Oct 6;6:51. doi: 10.1186/1745-6150-6-51.

5.

Histone deacetylases as regulators of inflammation and immunity.

Shakespear MR, Halili MA, Irvine KM, Fairlie DP, Sweet MJ.

Trends Immunol. 2011 Jul;32(7):335-43. doi: 10.1016/j.it.2011.04.001. Epub 2011 May 12. Review.

PMID:
21570914
6.

A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection.

Kim BH, Shenoy AR, Kumar P, Das R, Tiwari S, MacMicking JD.

Science. 2011 May 6;332(6030):717-21. doi: 10.1126/science.1201711.

7.

The specificity of innate immune responses is enforced by repression of interferon response elements by NF-κB p50.

Cheng CS, Feldman KE, Lee J, Verma S, Huang DB, Huynh K, Chang M, Ponomarenko JV, Sun SC, Benedict CA, Ghosh G, Hoffmann A.

Sci Signal. 2011 Feb 22;4(161):ra11. doi: 10.1126/scisignal.2001501.

8.

Targeting inflammation by modulating the Jun/AP-1 pathway.

Schonthaler HB, Guinea-Viniegra J, Wagner EF.

Ann Rheum Dis. 2011 Mar;70 Suppl 1:i109-12. doi: 10.1136/ard.2010.140533. Review.

PMID:
21339212
9.

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.

Bantscheff M, Hopf C, Savitski MM, Dittmann A, Grandi P, Michon AM, Schlegl J, Abraham Y, Becher I, Bergamini G, Boesche M, Delling M, Dümpelfeld B, Eberhard D, Huthmacher C, Mathieson T, Poeckel D, Reader V, Strunk K, Sweetman G, Kruse U, Neubauer G, Ramsden NG, Drewes G.

Nat Biotechnol. 2011 Mar;29(3):255-65. doi: 10.1038/nbt.1759. Epub 2011 Jan 23.

PMID:
21258344
10.

The genomic landscapes of inflammation.

Natoli G, Ghisletti S, Barozzi I.

Genes Dev. 2011 Jan 15;25(2):101-6. doi: 10.1101/gad.2018811. Review.

11.

Suppression of inflammation by a synthetic histone mimic.

Nicodeme E, Jeffrey KL, Schaefer U, Beinke S, Dewell S, Chung CW, Chandwani R, Marazzi I, Wilson P, Coste H, White J, Kirilovsky J, Rice CM, Lora JM, Prinjha RK, Lee K, Tarakhovsky A.

Nature. 2010 Dec 23;468(7327):1119-23. doi: 10.1038/nature09589. Epub 2010 Nov 10.

12.

A feed-forward circuit controlling inducible NF-κB target gene activation by promoter histone demethylation.

van Essen D, Zhu Y, Saccani S.

Mol Cell. 2010 Sep 10;39(5):750-60. doi: 10.1016/j.molcel.2010.08.010.

13.

Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate.

Hu Y, Lu W, Chen G, Zhang H, Jia Y, Wei Y, Yang H, Zhang W, Fiskus W, Bhalla K, Keating M, Huang P, Garcia-Manero G.

Blood. 2010 Oct 14;116(15):2732-41. doi: 10.1182/blood-2009-11-256354. Epub 2010 Jun 21.

14.

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities.

Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK.

Mol Cell. 2010 May 28;38(4):576-89. doi: 10.1016/j.molcel.2010.05.004.

15.

Functional crosstalk between type I and II interferon through the regulated expression of STAT1.

Gough DJ, Messina NL, Hii L, Gould JA, Sabapathy K, Robertson AP, Trapani JA, Levy DE, Hertzog PJ, Clarke CJ, Johnstone RW.

PLoS Biol. 2010 Apr 27;8(4):e1000361. doi: 10.1371/journal.pbio.1000361.

16.

Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids.

Groeger AL, Cipollina C, Cole MP, Woodcock SR, Bonacci G, Rudolph TK, Rudolph V, Freeman BA, Schopfer FJ.

Nat Chem Biol. 2010 Jun;6(6):433-41. doi: 10.1038/nchembio.367. Epub 2010 May 2.

17.

Selective transcription in response to an inflammatory stimulus.

Smale ST.

Cell. 2010 Mar 19;140(6):833-44. doi: 10.1016/j.cell.2010.01.037. Review.

18.

Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages.

Ghisletti S, Barozzi I, Mietton F, Polletti S, De Santa F, Venturini E, Gregory L, Lonie L, Chew A, Wei CL, Ragoussis J, Natoli G.

Immunity. 2010 Mar 26;32(3):317-28. doi: 10.1016/j.immuni.2010.02.008. Epub 2010 Mar 4.

19.

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression.

Park EJ, Lee JH, Yu GY, He G, Ali SR, Holzer RG, Osterreicher CH, Takahashi H, Karin M.

Cell. 2010 Jan 22;140(2):197-208. doi: 10.1016/j.cell.2009.12.052.

20.

Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue.

Grabiec AM, Krausz S, de Jager W, Burakowski T, Groot D, Sanders ME, Prakken BJ, Maslinski W, Eldering E, Tak PP, Reedquist KA.

J Immunol. 2010 Mar 1;184(5):2718-28. doi: 10.4049/jimmunol.0901467. Epub 2010 Jan 25.

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