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Items: 1 to 20 of 62

1.

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

Soler Artigas M, Loth DW, Wain LV, Gharib SA, Obeidat M, Tang W, Zhai G, Zhao JH, Smith AV, Huffman JE, Albrecht E, Jackson CM, Evans DM, Cadby G, Fornage M, Manichaikul A, Lopez LM, Johnson T, Aldrich MC, Aspelund T, Barroso I, Campbell H, Cassano PA, Couper DJ, Eiriksdottir G, Franceschini N, Garcia M, Gieger C, Gislason GK, Grkovic I, Hammond CJ, Hancock DB, Harris TB, Ramasamy A, Heckbert SR, Heliövaara M, Homuth G, Hysi PG, James AL, Jankovic S, Joubert BR, Karrasch S, Klopp N, Koch B, Kritchevsky SB, Launer LJ, Liu Y, Loehr LR, Lohman K, Loos RJ, Lumley T, Al Balushi KA, Ang WQ, Barr RG, Beilby J, Blakey JD, Boban M, Boraska V, Brisman J, Britton JR, Brusselle GG, Cooper C, Curjuric I, Dahgam S, Deary IJ, Ebrahim S, Eijgelsheim M, Francks C, Gaysina D, Granell R, Gu X, Hankinson JL, Hardy R, Harris SE, Henderson J, Henry A, Hingorani AD, Hofman A, Holt PG, Hui J, Hunter ML, Imboden M, Jameson KA, Kerr SM, Kolcic I, Kronenberg F, Liu JZ, Marchini J, McKeever T, Morris AD, Olin AC, Porteous DJ, Postma DS, Rich SS, Ring SM, Rivadeneira F, Rochat T, Sayer AA, Sayers I, Sly PD, Smith GD, Sood A, Starr JM, Uitterlinden AG, Vonk JM, Wannamethee SG, Whincup PH, Wijmenga C, Williams OD, Wong A, Mangino M, Marciante KD, McArdle WL, Meibohm B, Morrison AC, North KE, Omenaas E, Palmer LJ, Pietiläinen KH, Pin I, Pola Sbreve Ek O, Pouta A, Psaty BM, Hartikainen AL, Rantanen T, Ripatti S, Rotter JI, Rudan I, Rudnicka AR, Schulz H, Shin SY, Spector TD, Surakka I, Vitart V, Völzke H, Wareham NJ, Warrington NM, Wichmann HE, Wild SH, Wilk JB, Wjst M, Wright AF, Zgaga L, Zemunik T, Pennell CE, Nyberg F, Kuh D, Holloway JW, Boezen HM, Lawlor DA, Morris RW, Probst-Hensch N; International Lung Cancer Consortium.; GIANT consortium., Kaprio J, Wilson JF, Hayward C, Kähönen M, Heinrich J, Musk AW, Jarvis DL, Gläser S, Järvelin MR, Ch Stricker BH, Elliott P, O'Connor GT, Strachan DP, London SJ, Hall IP, Gudnason V, Tobin MD.

Nat Genet. 2011 Sep 25;43(11):1082-90. doi: 10.1038/ng.941.

2.

A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample.

Obeidat M, Wain LV, Shrine N, Kalsheker N, Soler Artigas M, Repapi E, Burton PR, Johnson T, Ramasamy A, Zhao JH, Zhai G, Huffman JE, Vitart V, Albrecht E, Igl W, Hartikainen AL, Pouta A, Cadby G, Hui J, Palmer LJ, Hadley D, McArdle WL, Rudnicka AR, Barroso I, Loos RJ, Wareham NJ, Mangino M, Soranzo N, Spector TD, Gläser S, Homuth G, Völzke H, Deloukas P, Granell R, Henderson J, Grkovic I, Jankovic S, Zgaga L, Polašek O, Rudan I, Wright AF, Campbell H, Wild SH, Wilson JF, Heinrich J, Imboden M, Probst-Hensch NM, Gyllensten U, Johansson Å, Zaboli G, Mustelin L, Rantanen T, Surakka I, Kaprio J, Jarvelin MR, Hayward C, Evans DM, Koch B, Musk AW, Elliott P, Strachan DP, Tobin MD, Sayers I, Hall IP; SpiroMeta Consortium..

PLoS One. 2011;6(5):e19382. doi: 10.1371/journal.pone.0019382. Epub 2011 May 20.

3.

Gene set analysis of SNP data: benefits, challenges, and future directions.

Fridley BL, Biernacka JM.

Eur J Hum Genet. 2011 Aug;19(8):837-43. doi: 10.1038/ejhg.2011.57. Epub 2011 Apr 13. Review.

4.

Gene-environment interaction for childhood asthma and exposure to farming in Central Europe.

Ege MJ, Strachan DP, Cookson WO, Moffatt MF, Gut I, Lathrop M, Kabesch M, Genuneit J, Büchele G, Sozanska B, Boznanski A, Cullinan P, Horak E, Bieli C, Braun-Fahrländer C, Heederik D, von Mutius E; GABRIELA Study Group..

J Allergy Clin Immunol. 2011 Jan;127(1):138-44, 144.e1-4. doi: 10.1016/j.jaci.2010.09.041.

PMID:
21211648
5.

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes.

Li Y, Willer CJ, Ding J, Scheet P, Abecasis GR.

Genet Epidemiol. 2010 Dec;34(8):816-34. doi: 10.1002/gepi.20533.

6.

Forced vital capacity, airway obstruction and survival in a general population sample from the USA.

Burney PG, Hooper R.

Thorax. 2011 Jan;66(1):49-54. doi: 10.1136/thx.2010.147041. Epub 2010 Oct 26.

PMID:
20980245
7.

Particulate matter-induced health effects: who is susceptible?

Sacks JD, Stanek LW, Luben TJ, Johns DO, Buckley BJ, Brown JS, Ross M.

Environ Health Perspect. 2011 Apr;119(4):446-54. doi: 10.1289/ehp.1002255. Epub 2010 Oct 20. Review.

8.

A large-scale, consortium-based genomewide association study of asthma.

Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, von Mutius E, Farrall M, Lathrop M, Cookson WO; GABRIEL Consortium..

N Engl J Med. 2010 Sep 23;363(13):1211-21. doi: 10.1056/NEJMoa0906312.

9.

The genetics of obstructive lung disease: big is beautiful.

Hall IP, Lomas DA.

Thorax. 2010 Sep;65(9):760-1. doi: 10.1136/thx.2010.147173. No abstract available.

PMID:
20805163
10.

Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease.

Pillai SG, Kong X, Edwards LD, Cho MH, Anderson WH, Coxson HO, Lomas DA, Silverman EK; ECLIPSE and ICGN Investigators..

Am J Respir Crit Care Med. 2010 Dec 15;182(12):1498-505. doi: 10.1164/rccm.201002-0151OC. Epub 2010 Jul 23.

11.

Markers of anti-oxidant response in tobacco smoke exposed subjects: a data-mining review.

Comandini A, Marzano V, Curradi G, Federici G, Urbani A, Saltini C.

Pulm Pharmacol Ther. 2010 Dec;23(6):482-92. doi: 10.1016/j.pupt.2010.05.006. Epub 2010 Jun 1. Review.

PMID:
20594977
12.

ProbABEL package for genome-wide association analysis of imputed data.

Aulchenko YS, Struchalin MV, van Duijn CM.

BMC Bioinformatics. 2010 Mar 16;11:134. doi: 10.1186/1471-2105-11-134.

13.

Dust exposure assessed by a job exposure matrix is associated with increased annual decline in FEV1: a 5-year prospective study of employees in Norwegian smelters.

Johnsen HL, Hetland SM, Benth JS, Kongerud J, Søyseth V.

Am J Respir Crit Care Med. 2010 Jun 1;181(11):1234-40. doi: 10.1164/rccm.200809-1381OC. Epub 2010 Mar 4.

PMID:
20203247
14.

HMOX1 and GST variants modify attenuation of FEF25-75% decline due to PM10 reduction.

Curjuric I, Imboden M, Schindler C, Downs SH, Hersberger M, Liu SL, Matyas G, Russi EW, Schwartz J, Thun GA, Postma DS, Rochat T, Probst-Hensch NM; SAPALDIA team..

Eur Respir J. 2010 Mar;35(3):505-14. doi: 10.1183/09031936.00044309. Erratum in: Eur Respir J. 2010 Nov;36(5):1225.

15.

Variants in FAM13A are associated with chronic obstructive pulmonary disease.

Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, Hersh CP, DeMeo DL, Hunninghake GM, Litonjua AA, Sparrow D, Lange C, Won S, Murphy JR, Beaty TH, Regan EA, Make BJ, Hokanson JE, Crapo JD, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Pillai SG, Silverman EK.

Nat Genet. 2010 Mar;42(3):200-2. doi: 10.1038/ng.535. Epub 2010 Feb 21.

16.

Methods for investigating gene-environment interactions in candidate pathway and genome-wide association studies.

Thomas D.

Annu Rev Public Health. 2010;31:21-36. doi: 10.1146/annurev.publhealth.012809.103619. Review.

17.

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.

Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, Marciante KD, Franceschini N, van Durme YM, Chen TH, Barr RG, Schabath MB, Couper DJ, Brusselle GG, Psaty BM, van Duijn CM, Rotter JI, Uitterlinden AG, Hofman A, Punjabi NM, Rivadeneira F, Morrison AC, Enright PL, North KE, Heckbert SR, Lumley T, Stricker BH, O'Connor GT, London SJ.

Nat Genet. 2010 Jan;42(1):45-52. doi: 10.1038/ng.500. Epub 2009 Dec 13.

18.

Genome-wide association study identifies five loci associated with lung function.

Repapi E, Sayers I, Wain LV, Burton PR, Johnson T, Obeidat M, Zhao JH, Ramasamy A, Zhai G, Vitart V, Huffman JE, Igl W, Albrecht E, Deloukas P, Henderson J, Granell R, McArdle WL, Rudnicka AR; Wellcome Trust Case Control Consortium., Barroso I, Loos RJ, Wareham NJ, Mustelin L, Rantanen T, Surakka I, Imboden M, Wichmann HE, Grkovic I, Jankovic S, Zgaga L, Hartikainen AL, Peltonen L, Gyllensten U, Johansson A, Zaboli G, Campbell H, Wild SH, Wilson JF, Gläser S, Homuth G, Völzke H, Mangino M, Soranzo N, Spector TD, Polasek O, Rudan I, Wright AF, Heliövaara M, Ripatti S, Pouta A, Naluai AT, Olin AC, Torén K, Cooper MN, James AL, Palmer LJ, Hingorani AD, Wannamethee SG, Whincup PH, Smith GD, Ebrahim S, McKeever TM, Pavord ID, MacLeod AK, Morris AD, Porteous DJ, Cooper C, Dennison E, Shaheen S, Karrasch S, Schnabel E, Schulz H, Grallert H, Bouatia-Naji N, Delplanque J, Froguel P, Blakey JD; NSHD Respiratory Study Team., Britton JR, Morris RW, Holloway JW, Lawlor DA, Hui J, Nyberg F, Jarvelin MR, Jackson C, Kähönen M, Kaprio J, Probst-Hensch NM, Koch B, Hayward C, Evans DM, Elliott P, Strachan DP, Hall IP, Tobin MD.

Nat Genet. 2010 Jan;42(1):36-44. doi: 10.1038/ng.501. Epub 2009 Dec 13.

19.

Hedgehog-interacting protein is a COPD susceptibility gene: the Rotterdam Study.

Van Durme YM, Eijgelsheim M, Joos GF, Hofman A, Uitterlinden AG, Brusselle GG, Stricker BH.

Eur Respir J. 2010 Jul;36(1):89-95. doi: 10.1183/09031936.00129509. Epub 2009 Dec 8.

20.

Particulate matter and atherosclerosis: role of particle size, composition and oxidative stress.

Araujo JA, Nel AE.

Part Fibre Toxicol. 2009 Sep 18;6:24. doi: 10.1186/1743-8977-6-24.

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