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Items: 1 to 20 of 24

1.

Human TH17 cells are long-lived effector memory cells.

Kryczek I, Zhao E, Liu Y, Wang Y, Vatan L, Szeliga W, Moyer J, Klimczak A, Lange A, Zou W.

Sci Transl Med. 2011 Oct 12;3(104):104ra100. doi: 10.1126/scitranslmed.3002949.

2.

Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1.

Dang EV, Barbi J, Yang HY, Jinasena D, Yu H, Zheng Y, Bordman Z, Fu J, Kim Y, Yen HR, Luo W, Zeller K, Shimoda L, Topalian SL, Semenza GL, Dang CV, Pardoll DM, Pan F.

Cell. 2011 Sep 2;146(5):772-84. doi: 10.1016/j.cell.2011.07.033. Epub 2011 Aug 25.

3.

Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression.

Li J, Lau GK, Chen L, Dong SS, Lan HY, Huang XR, Li Y, Luk JM, Yuan YF, Guan XY.

PLoS One. 2011;6(7):e21816. doi: 10.1371/journal.pone.0021816. Epub 2011 Jul 7.

4.

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.

Shi LZ, Wang R, Huang G, Vogel P, Neale G, Green DR, Chi H.

J Exp Med. 2011 Jul 4;208(7):1367-76. doi: 10.1084/jem.20110278. Epub 2011 Jun 27.

5.

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORĪ³t activity.

Huh JR, Leung MW, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, Rastinejad F, Littman DR.

Nature. 2011 Apr 28;472(7344):486-90. doi: 10.1038/nature09978. Epub 2011 Mar 27.

6.

Tumor-infiltrating CD4+ Th17 cells produce IL-17 in tumor microenvironment and promote tumor progression in human gastric cancer.

Iida T, Iwahashi M, Katsuda M, Ishida K, Nakamori M, Nakamura M, Naka T, Ojima T, Ueda K, Hayata K, Nakamura Y, Yamaue H.

Oncol Rep. 2011 May;25(5):1271-7. doi: 10.3892/or.2011.1201. Epub 2011 Mar 1.

PMID:
21369705
7.

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

Delgoffe GM, Pollizzi KN, Waickman AT, Heikamp E, Meyers DJ, Horton MR, Xiao B, Worley PF, Powell JD.

Nat Immunol. 2011 Apr;12(4):295-303. doi: 10.1038/ni.2005. Epub 2011 Feb 27.

8.

Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes.

Hot A, Miossec P.

Ann Rheum Dis. 2011 May;70(5):727-32. doi: 10.1136/ard.2010.143768. Epub 2011 Feb 22. Review.

PMID:
21345813
9.

Genetic controls of Th17 cell differentiation and plasticity.

Dong C.

Exp Mol Med. 2011 Jan 31;43(1):1-6. Review.

10.

The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism.

Powell JD, Delgoffe GM.

Immunity. 2010 Sep 24;33(3):301-11. doi: 10.1016/j.immuni.2010.09.002. Review.

11.

Regulatory T cells in tumor immunity.

Nishikawa H, Sakaguchi S.

Int J Cancer. 2010 Aug 15;127(4):759-67. doi: 10.1002/ijc.25429. Review.

12.

Hypoxia-inducible factors as essential regulators of inflammation.

Imtiyaz HZ, Simon MC.

Curr Top Microbiol Immunol. 2010;345:105-20. doi: 10.1007/82_2010_74. Review.

13.

Th17 and regulatory T cells in mediating and restraining inflammation.

Littman DR, Rudensky AY.

Cell. 2010 Mar 19;140(6):845-58. doi: 10.1016/j.cell.2010.02.021. Review.

14.

T helper 17 cells promote cytotoxic T cell activation in tumor immunity.

Martin-Orozco N, Muranski P, Chung Y, Yang XO, Yamazaki T, Lu S, Hwu P, Restifo NP, Overwijk WW, Dong C.

Immunity. 2009 Nov 20;31(5):787-98. doi: 10.1016/j.immuni.2009.09.014. Epub 2009 Oct 29.

15.

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses.

Wu S, Rhee KJ, Albesiano E, Rabizadeh S, Wu X, Yen HR, Huso DL, Brancati FL, Wick E, McAllister F, Housseau F, Pardoll DM, Sears CL.

Nat Med. 2009 Sep;15(9):1016-22. doi: 10.1038/nm.2015. Epub 2009 Aug 23.

16.

HIF-1 inhibitors for cancer therapy: from gene expression to drug discovery.

Semenza GL.

Curr Pharm Des. 2009;15(33):3839-43. Review.

PMID:
19671047
17.

mTOR: taking cues from the immune microenvironment.

Delgoffe GM, Powell JD.

Immunology. 2009 Aug;127(4):459-65. doi: 10.1111/j.1365-2567.2009.03125.x. Review.

18.

IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway.

Wang L, Yi T, Kortylewski M, Pardoll DM, Zeng D, Yu H.

J Exp Med. 2009 Jul 6;206(7):1457-64. doi: 10.1084/jem.20090207. Epub 2009 Jun 29.

19.

Plasticity of CD4+ T cell lineage differentiation.

Zhou L, Chong MM, Littman DR.

Immunity. 2009 May;30(5):646-55. doi: 10.1016/j.immuni.2009.05.001. Review.

20.

Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth.

Zhang H, Qian DZ, Tan YS, Lee K, Gao P, Ren YR, Rey S, Hammers H, Chang D, Pili R, Dang CV, Liu JO, Semenza GL.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19579-86. doi: 10.1073/pnas.0809763105. Epub 2008 Nov 19.

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