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Items: 1 to 20 of 56

1.

Visualization of the cocaine-sensitive dopamine transporter with ligand-conjugated quantum dots.

Kovtun O, Tomlinson ID, Sakrikar DS, Chang JC, Blakely RD, Rosenthal SJ.

ACS Chem Neurosci. 2011 Jul 20;2(7):370-8. doi: 10.1021/cn200032r. Epub 2011 Apr 26.

2.

Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior.

Veenstra-VanderWeele J, Muller CL, Iwamoto H, Sauer JE, Owens WA, Shah CR, Cohen J, Mannangatti P, Jessen T, Thompson BJ, Ye R, Kerr TM, Carneiro AM, Crawley JN, Sanders-Bush E, McMahon DG, Ramamoorthy S, Daws LC, Sutcliffe JS, Blakely RD.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5469-74. doi: 10.1073/pnas.1112345109. Epub 2012 Mar 19.

3.

A fluorescence displacement assay for antidepressant drug discovery based on ligand-conjugated quantum dots.

Chang JC, Tomlinson ID, Warnement MR, Iwamoto H, DeFelice LJ, Blakely RD, Rosenthal SJ.

J Am Chem Soc. 2011 Nov 9;133(44):17528-31. doi: 10.1021/ja204301g. Epub 2011 Oct 17.

4.

Colocalization and regulated physical association of presynaptic serotonin transporters with A₃ adenosine receptors.

Zhu CB, Lindler KM, Campbell NG, Sutcliffe JS, Hewlett WA, Blakely RD.

Mol Pharmacol. 2011 Sep;80(3):458-65. doi: 10.1124/mol.111.071399. Epub 2011 Jun 24.

5.

Regulation of monoamine transporters: Role of transporter phosphorylation.

Ramamoorthy S, Shippenberg TS, Jayanthi LD.

Pharmacol Ther. 2011 Feb;129(2):220-38. doi: 10.1016/j.pharmthera.2010.09.009. Epub 2010 Oct 15. Review.

6.

Kinetics of G-protein-coupled receptor endosomal trafficking pathways revealed by single quantum dots.

Fichter KM, Flajolet M, Greengard P, Vu TQ.

Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18658-63. doi: 10.1073/pnas.1013763107. Epub 2010 Oct 12.

7.

Revitalizing membrane rafts: new tools and insights.

Simons K, Gerl MJ.

Nat Rev Mol Cell Biol. 2010 Oct;11(10):688-99. doi: 10.1038/nrm2977. Review.

PMID:
20861879
8.

Interleukin-1 receptor activation by systemic lipopolysaccharide induces behavioral despair linked to MAPK regulation of CNS serotonin transporters.

Zhu CB, Lindler KM, Owens AW, Daws LC, Blakely RD, Hewlett WA.

Neuropsychopharmacology. 2010 Dec;35(13):2510-20. doi: 10.1038/npp.2010.116. Epub 2010 Sep 8.

9.

Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding.

Hong WC, Amara SG.

J Biol Chem. 2010 Oct 15;285(42):32616-26. doi: 10.1074/jbc.M110.150565. Epub 2010 Aug 5.

10.

cGMP-dependent protein kinase Ialpha associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake.

Steiner JA, Carneiro AM, Wright J, Matthies HJ, Prasad HC, Nicki CK, Dostmann WR, Buchanan CC, Corbin JD, Francis SH, Blakely RD.

Mol Brain. 2009 Aug 5;2:26. doi: 10.1186/1756-6606-2-26.

11.

Lovastatin potentiates the antidepressant efficacy of fluoxetine in rats.

Renshaw PF, Parsegian A, Yang CK, Novero A, Yoon SJ, Lyoo IK, Cohen BM, Carlezon WA Jr.

Pharmacol Biochem Behav. 2009 Mar;92(1):88-92. doi: 10.1016/j.pbb.2008.10.017. Epub 2008 Nov 5.

12.

Enhanced activity of human serotonin transporter variants associated with autism.

Prasad HC, Steiner JA, Sutcliffe JS, Blakely RD.

Philos Trans R Soc Lond B Biol Sci. 2009 Jan 27;364(1514):163-73. doi: 10.1098/rstb.2008.0143.

13.

How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems.

Murphy DL, Fox MA, Timpano KR, Moya PR, Ren-Patterson R, Andrews AM, Holmes A, Lesch KP, Wendland JR.

Neuropharmacology. 2008 Nov;55(6):932-60. doi: 10.1016/j.neuropharm.2008.08.034. Epub 2008 Sep 11. Review.

14.

Activation-dependent hindrance of photoreceptor G protein diffusion by lipid microdomains.

Wang Q, Zhang X, Zhang L, He F, Zhang G, Jamrich M, Wensel TG.

J Biol Chem. 2008 Oct 31;283(44):30015-24. doi: 10.1074/jbc.M803953200. Epub 2008 Aug 18.

15.

Structural determinants of species-selective substrate recognition in human and Drosophila serotonin transporters revealed through computational docking studies.

Kaufmann KW, Dawson ES, Henry LK, Field JR, Blakely RD, Meiler J.

Proteins. 2009 Feb 15;74(3):630-42. doi: 10.1002/prot.22178.

16.

Robust single-particle tracking in live-cell time-lapse sequences.

Jaqaman K, Loerke D, Mettlen M, Kuwata H, Grinstein S, Schmid SL, Danuser G.

Nat Methods. 2008 Aug;5(8):695-702. doi: 10.1038/nmeth.1237. Epub 2008 Jul 20.

17.

Going with the flow: trafficking-dependent and -independent regulation of serotonin transport.

Steiner JA, Carneiro AM, Blakely RD.

Traffic. 2008 Sep;9(9):1393-402. doi: 10.1111/j.1600-0854.2008.00757.x. Epub 2008 Apr 28. Review.

18.

Monovalent, reduced-size quantum dots for imaging receptors on living cells.

Howarth M, Liu W, Puthenveetil S, Zheng Y, Marshall LF, Schmidt MM, Wittrup KD, Bawendi MG, Ting AY.

Nat Methods. 2008 May;5(5):397-9. doi: 10.1038/nmeth.1206. Epub 2008 Apr 20.

19.

Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans.

Carneiro AM, Cook EH, Murphy DL, Blakely RD.

J Clin Invest. 2008 Apr;118(4):1544-52. doi: 10.1172/JCI33374.

20.

Single-molecule tracking.

Vrljic M, Nishimura SY, Moerner WE.

Methods Mol Biol. 2007;398:193-219. doi: 10.1007/978-1-59745-513-8_14.

PMID:
18214382

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