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Items: 1 to 20 of 75

1.

Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation.

Leuner K, Schütt T, Kurz C, Eckert SH, Schiller C, Occhipinti A, Mai S, Jendrach M, Eckert GP, Kruse SE, Palmiter RD, Brandt U, Dröse S, Wittig I, Willem M, Haass C, Reichert AS, Müller WE.

Antioxid Redox Signal. 2012 Jun 15;16(12):1421-33. doi: 10.1089/ars.2011.4173. Epub 2012 Feb 28.

2.

Sex hormones, aging, and Alzheimer's disease.

Barron AM, Pike CJ.

Front Biosci (Elite Ed). 2012 Jan 1;4:976-97. Review.

3.

Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol.

Lim YA, Grimm A, Giese M, Mensah-Nyagan AG, Villafranca JE, Ittner LM, Eckert A, Götz J.

PLoS One. 2011;6(12):e28887. doi: 10.1371/journal.pone.0028887. Epub 2011 Dec 12.

4.

Insights into mitochondrial dysfunction: aging, amyloid-β, and tau-A deleterious trio.

Schmitt K, Grimm A, Kazmierczak A, Strosznajder JB, Götz J, Eckert A.

Antioxid Redox Signal. 2012 Jun 15;16(12):1456-66. doi: 10.1089/ars.2011.4400. Epub 2012 Jan 30. Review.

PMID:
22117646
5.

Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease.

Chen S, Wang JM, Irwin RW, Yao J, Liu L, Brinton RD.

PLoS One. 2011;6(8):e24293. doi: 10.1371/journal.pone.0024293. Epub 2011 Aug 30.

6.
7.

Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid.

Yao J, Irwin R, Chen S, Hamilton R, Cadenas E, Brinton RD.

Neurobiol Aging. 2012 Aug;33(8):1507-21. doi: 10.1016/j.neurobiolaging.2011.03.001. Epub 2011 Apr 22.

8.

Behavioral stress causes mitochondrial dysfunction via ABAD up-regulation and aggravates plaque pathology in the brain of a mouse model of Alzheimer disease.

Seo JS, Lee KW, Kim TK, Baek IS, Im JY, Han PL.

Free Radic Biol Med. 2011 Jun 1;50(11):1526-35. doi: 10.1016/j.freeradbiomed.2011.02.035. Epub 2011 Mar 5.

PMID:
21382475
9.

Development and evaluation of polymer nanoparticles for oral delivery of estradiol to rat brain in a model of Alzheimer's pathology.

Mittal G, Carswell H, Brett R, Currie S, Kumar MN.

J Control Release. 2011 Mar 10;150(2):220-8. doi: 10.1016/j.jconrel.2010.11.013. Epub 2010 Nov 24.

PMID:
21111014
10.

Alzheimer disease.

Castellani RJ, Rolston RK, Smith MA.

Dis Mon. 2010 Sep;56(9):484-546. doi: 10.1016/j.disamonth.2010.06.001. Review. No abstract available.

11.

Metabolic impact of estrogen signalling through ERalpha and ERbeta.

Foryst-Ludwig A, Kintscher U.

J Steroid Biochem Mol Biol. 2010 Oct;122(1-3):74-81. doi: 10.1016/j.jsbmb.2010.06.012. Epub 2010 Jul 3. Review.

PMID:
20599505
12.

Menopause and mitochondria: windows into estrogen effects on Alzheimer's disease risk and therapy.

Henderson VW, Brinton RD.

Prog Brain Res. 2010;182:77-96. doi: 10.1016/S0079-6123(10)82003-5.

PMID:
20541661
13.

Neuroprotective mechanism conferred by 17beta-estradiol on the biochemical basis of Alzheimer's disease.

Amtul Z, Wang L, Westaway D, Rozmahel RF.

Neuroscience. 2010 Aug 25;169(2):781-6. doi: 10.1016/j.neuroscience.2010.05.031. Epub 2010 May 21.

PMID:
20493928
14.

Why women have more Alzheimer's disease than men: gender and mitochondrial toxicity of amyloid-beta peptide.

Viña J, Lloret A.

J Alzheimers Dis. 2010;20 Suppl 2:S527-33. doi: 10.3233/JAD-2010-100501. Review.

PMID:
20442496
15.

Sex steroids to maintain cognitive function in women after the menopause: a meta-analyses of treatment trials.

Hogervorst E, Bandelow S.

Maturitas. 2010 May;66(1):56-71. doi: 10.1016/j.maturitas.2010.02.005. Epub 2010 Mar 4. Review.

PMID:
20202765
16.

Estrogen therapy and cognition: a review of the cholinergic hypothesis.

Gibbs RB.

Endocr Rev. 2010 Apr;31(2):224-53. doi: 10.1210/er.2009-0036. Epub 2009 Dec 17. Review.

17.

Mitochondrial mechanisms of estrogen neuroprotection.

Simpkins JW, Yi KD, Yang SH, Dykens JA.

Biochim Biophys Acta. 2010 Oct;1800(10):1113-20. doi: 10.1016/j.bbagen.2009.11.013. Epub 2009 Nov 26. Review.

18.

Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice.

Grueninger F, Bohrmann B, Czech C, Ballard TM, Frey JR, Weidensteiner C, von Kienlin M, Ozmen L.

Neurobiol Dis. 2010 Feb;37(2):294-306. doi: 10.1016/j.nbd.2009.09.004. Epub 2009 Sep 23.

PMID:
19781645
19.

Enhanced levels of mitochondrial enzyme 17beta-hydroxysteroid dehydrogenase type 10 in patients with Alzheimer disease and multiple sclerosis.

Kristofiková Z, Bocková M, Hegnerová K, Bartos A, Klaschka J, Rícný J, Rípová D, Homola J.

Mol Biosyst. 2009 Oct;5(10):1174-9. doi: 10.1039/b904799a. Epub 2009 Jul 6.

PMID:
19756307
20.

Direct antioxidant and protective effect of estradiol on isolated mitochondria.

Borrás C, Gambini J, López-Grueso R, Pallardó FV, Viña J.

Biochim Biophys Acta. 2010 Jan;1802(1):205-11. doi: 10.1016/j.bbadis.2009.09.007. Epub 2009 Sep 12.

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