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Items: 1 to 20 of 26

1.

Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme.

Henderson BR, Saeedi BJ, Campagnola G, Geiss BJ.

PLoS One. 2011;6(10):e25795. doi: 10.1371/journal.pone.0025795.

2.

A high-throughput screening assay for the identification of flavivirus NS5 capping enzyme GTP-binding inhibitors: implications for antiviral drug development.

Geiss BJ, Stahla-Beek HJ, Hannah AM, Gari HH, Henderson BR, Saeedi BJ, Keenan SM.

J Biomol Screen. 2011 Sep;16(8):852-61. doi: 10.1177/1087057111412183.

3.

Infectious alphavirus production from a simple plasmid transfection+.

Steel JJ, Henderson BR, Lama SB, Olson KE, Geiss BJ.

Virol J. 2011 Jul 19;8:356. doi: 10.1186/1743-422X-8-356.

4.

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

Züst R, Cervantes-Barragan L, Habjan M, Maier R, Neuman BW, Ziebuhr J, Szretter KJ, Baker SC, Barchet W, Diamond MS, Siddell SG, Ludewig B, Thiel V.

Nat Immunol. 2011 Feb;12(2):137-43. doi: 10.1038/ni.1979.

5.

Small molecule inhibitors that selectively block dengue virus methyltransferase.

Lim SP, Sonntag LS, Noble C, Nilar SH, Ng RH, Zou G, Monaghan P, Chung KY, Dong H, Liu B, Bodenreider C, Lee G, Ding M, Chan WL, Wang G, Jian YL, Chao AT, Lescar J, Yin Z, Vedananda TR, Keller TH, Shi PY.

J Biol Chem. 2011 Feb 25;286(8):6233-40. doi: 10.1074/jbc.M110.179184.

6.

2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members.

Daffis S, Szretter KJ, Schriewer J, Li J, Youn S, Errett J, Lin TY, Schneller S, Zust R, Dong H, Thiel V, Sen GC, Fensterl V, Klimstra WB, Pierson TC, Buller RM, Gale M Jr, Shi PY, Diamond MS.

Nature. 2010 Nov 18;468(7322):452-6. doi: 10.1038/nature09489.

7.

Update on the global spread of dengue.

Guzman A, Istúriz RE.

Int J Antimicrob Agents. 2010 Nov;36 Suppl 1:S40-2. doi: 10.1016/j.ijantimicag.2010.06.018. Review.

PMID:
20833000
8.

Focus on flaviviruses: current and future drug targets.

Geiss BJ, Stahla H, Hannah AM, Gari AM, Keenan SM.

Future Med Chem. 2009 May;1(2):327-44. doi: 10.4155/fmc.09.27. Review.

9.

The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure.

Issur M, Geiss BJ, Bougie I, Picard-Jean F, Despins S, Mayette J, Hobdey SE, Bisaillon M.

RNA. 2009 Dec;15(12):2340-50. doi: 10.1261/rna.1609709.

10.

Monoclonal antibodies to the West Nile virus NS5 protein map to linear and conformational epitopes in the methyltransferase and polymerase domains.

Hall RA, Tan SE, Selisko B, Slade R, Hobson-Peters J, Canard B, Hughes M, Leung JY, Balmori-Melian E, Hall-Mendelin S, Pham KB, Clark DC, Prow NA, Khromykh AA.

J Gen Virol. 2009 Dec;90(Pt 12):2912-22. doi: 10.1099/vir.0.013805-0.

PMID:
19710254
11.

Identification and characterization of inhibitors of West Nile virus.

Puig-Basagoiti F, Qing M, Dong H, Zhang B, Zou G, Yuan Z, Shi PY.

Antiviral Res. 2009 Jul;83(1):71-9. doi: 10.1016/j.antiviral.2009.03.005.

12.

The flaviviral methyltransferase is a substrate of Casein Kinase 1.

Bhattacharya D, Ansari IH, Striker R.

Virus Res. 2009 Apr;141(1):101-4. doi: 10.1016/j.virusres.2009.01.002.

13.

Analysis of flavivirus NS5 methyltransferase cap binding.

Geiss BJ, Thompson AA, Andrews AJ, Sons RL, Gari HH, Keenan SM, Peersen OB.

J Mol Biol. 2009 Feb 6;385(5):1643-54. doi: 10.1016/j.jmb.2008.11.058.

14.

Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus.

Bollati M, Milani M, Mastrangelo E, Ricagno S, Tedeschi G, Nonnis S, Decroly E, Selisko B, de Lamballerie X, Coutard B, Canard B, Bolognesi M.

J Mol Biol. 2009 Jan 9;385(1):140-52. doi: 10.1016/j.jmb.2008.10.028.

PMID:
18976670
15.

Phosphorylation of yellow fever virus NS5 alters methyltransferase activity.

Bhattacharya D, Hoover S, Falk SP, Weisblum B, Vestling M, Striker R.

Virology. 2008 Oct 25;380(2):276-84. doi: 10.1016/j.virol.2008.07.013.

16.

Epalrestat: an aldose reductase inhibitor for the treatment of diabetic neuropathy.

Ramirez MA, Borja NL.

Pharmacotherapy. 2008 May;28(5):646-55. doi: 10.1592/phco.28.5.646. Review.

PMID:
18447661
17.

Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5.

Egloff MP, Decroly E, Malet H, Selisko B, Benarroch D, Ferron F, Canard B.

J Mol Biol. 2007 Sep 21;372(3):723-36.

PMID:
17686489
18.

Structural bases for substrate recognition and activity in Meaban virus nucleoside-2'-O-methyltransferase.

Mastrangelo E, Bollati M, Milani M, Selisko B, Peyrane F, Canard B, Grard G, de Lamballerie X, Bolognesi M.

Protein Sci. 2007 Jun;16(6):1133-45.

19.

Structure and function of flavivirus NS5 methyltransferase.

Zhou Y, Ray D, Zhao Y, Dong H, Ren S, Li Z, Guo Y, Bernard KA, Shi PY, Li H.

J Virol. 2007 Apr;81(8):3891-903.

20.

Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo.

Whitby K, Pierson TC, Geiss B, Lane K, Engle M, Zhou Y, Doms RW, Diamond MS.

J Virol. 2005 Jul;79(14):8698-706.

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