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Items: 1 to 20 of 49

1.

Hul5 HECT ubiquitin ligase plays a major role in the ubiquitylation and turnover of cytosolic misfolded proteins.

Fang NN, Ng AH, Measday V, Mayor T.

Nat Cell Biol. 2011 Oct 9;13(11):1344-52. doi: 10.1038/ncb2343.

2.

UBR1 promotes protein kinase quality control and sensitizes cells to Hsp90 inhibition.

Sultana R, Theodoraki MA, Caplan AJ.

Exp Cell Res. 2012 Jan 1;318(1):53-60. doi: 10.1016/j.yexcr.2011.09.010. Epub 2011 Sep 29.

3.

Nuclear protein quality is regulated by the ubiquitin-proteasome system through the activity of Ubc4 and San1 in fission yeast.

Matsuo Y, Kishimoto H, Tanae K, Kitamura K, Katayama S, Kawamukai M.

J Biol Chem. 2011 Apr 15;286(15):13775-90. doi: 10.1074/jbc.M110.169953. Epub 2011 Feb 15.

4.

Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates.

Rosenbaum JC, Fredrickson EK, Oeser ML, Garrett-Engele CM, Locke MN, Richardson LA, Nelson ZW, Hetrick ED, Milac TI, Gottschling DE, Gardner RG.

Mol Cell. 2011 Jan 7;41(1):93-106. doi: 10.1016/j.molcel.2010.12.004.

5.

Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.

Buchberger A, Bukau B, Sommer T.

Mol Cell. 2010 Oct 22;40(2):238-52. doi: 10.1016/j.molcel.2010.10.001. Review.

6.

Making temperature-sensitive mutants.

Ben-Aroya S, Pan X, Boeke JD, Hieter P.

Methods Enzymol. 2010;470:181-204. doi: 10.1016/S0076-6879(10)70008-2. Epub 2010 Mar 1.

7.

Synthetic genetic array (SGA) analysis in Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Baryshnikova A, Costanzo M, Dixon S, Vizeacoumar FJ, Myers CL, Andrews B, Boone C.

Methods Enzymol. 2010;470:145-79. doi: 10.1016/S0076-6879(10)70007-0. Epub 2010 Mar 1.

PMID:
20946810
8.

Role of a ribosome-associated E3 ubiquitin ligase in protein quality control.

Bengtson MH, Joazeiro CA.

Nature. 2010 Sep 23;467(7314):470-3. doi: 10.1038/nature09371. Epub 2010 Sep 12.

9.

Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins.

Nillegoda NB, Theodoraki MA, Mandal AK, Mayo KJ, Ren HY, Sultana R, Wu K, Johnson J, Cyr DM, Caplan AJ.

Mol Biol Cell. 2010 Jul 1;21(13):2102-16. doi: 10.1091/mbc.E10-02-0098. Epub 2010 May 12.

10.

A nucleus-based quality control mechanism for cytosolic proteins.

Prasad R, Kawaguchi S, Ng DT.

Mol Biol Cell. 2010 Jul 1;21(13):2117-27. doi: 10.1091/mbc.E10-02-0111. Epub 2010 May 12.

11.

Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1.

Heck JW, Cheung SK, Hampton RY.

Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1106-11. doi: 10.1073/pnas.0910591107. Epub 2009 Dec 28.

12.

Recognition and processing of ubiquitin-protein conjugates by the proteasome.

Finley D.

Annu Rev Biochem. 2009;78:477-513. doi: 10.1146/annurev.biochem.78.081507.101607. Review.

13.

Inefficient quality control of thermosensitive proteins on the plasma membrane.

Lewis MJ, Pelham HR.

PLoS One. 2009;4(4):e5038. doi: 10.1371/journal.pone.0005038. Epub 2009 Apr 1.

14.

The ubiquitylation machinery of the endoplasmic reticulum.

Hirsch C, Gauss R, Horn SC, Neuber O, Sommer T.

Nature. 2009 Mar 26;458(7237):453-60. doi: 10.1038/nature07962. Review.

PMID:
19325625
15.

Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1.

Eisele F, Wolf DH.

FEBS Lett. 2008 Dec 24;582(30):4143-6. doi: 10.1016/j.febslet.2008.11.015. Epub 2008 Nov 27.

16.

Degradation of a cytosolic protein requires endoplasmic reticulum-associated degradation machinery.

Metzger MB, Maurer MJ, Dancy BM, Michaelis S.

J Biol Chem. 2008 Nov 21;283(47):32302-16. doi: 10.1074/jbc.M806424200. Epub 2008 Sep 23.

17.

Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae.

Ben-Aroya S, Coombes C, Kwok T, O'Donnell KA, Boeke JD, Hieter P.

Mol Cell. 2008 Apr 25;30(2):248-58. doi: 10.1016/j.molcel.2008.02.021.

18.

Protein quality control in the early secretory pathway.

Anelli T, Sitia R.

EMBO J. 2008 Jan 23;27(2):315-27. doi: 10.1038/sj.emboj.7601974. Review.

19.

Protein quality control in neurodegeneration: walking the tight rope between health and disease.

Hol EM, Scheper W.

J Mol Neurosci. 2008;34(1):23-33. Epub 2007 Mar 24. Review.

PMID:
18157655
20.

Protein quality control: the who's who, the where's and therapeutic escapes.

Roth J, Yam GH, Fan J, Hirano K, Gaplovska-Kysela K, Le Fourn V, Guhl B, Santimaria R, Torossi T, Ziak M, Zuber C.

Histochem Cell Biol. 2008 Feb;129(2):163-77. Epub 2007 Dec 13. Review.

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