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Items: 9

1.

Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients.

Breda L, Casu C, Gardenghi S, Bianchi N, Cartegni L, Narla M, Yazdanbakhsh K, Musso M, Manwani D, Little J, Gardner LB, Kleinert DA, Prus E, Fibach E, Grady RW, Giardina PJ, Gambari R, Rivella S.

PLoS One. 2012;7(3):e32345. doi: 10.1371/journal.pone.0032345.

2.

Integrated protein quality-control pathways regulate free α-globin in murine β-thalassemia.

Khandros E, Thom CS, D'Souza J, Weiss MJ.

Blood. 2012 May 31;119(22):5265-75. doi: 10.1182/blood-2011-12-397729.

3.

Kinetics of α-globin binding to α-hemoglobin stabilizing protein (AHSP) indicate preferential stabilization of hemichrome folding intermediate.

Mollan TL, Khandros E, Weiss MJ, Olson JS.

J Biol Chem. 2012 Mar 30;287(14):11338-50. doi: 10.1074/jbc.M111.313247.

4.

Sickle-cell disease.

Rees DC, Williams TN, Gladwin MT.

Lancet. 2010 Dec 11;376(9757):2018-31. doi: 10.1016/S0140-6736(10)61029-X. Review.

PMID:
21131035
5.

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.

Gardenghi S, Ramos P, Marongiu MF, Melchiori L, Breda L, Guy E, Muirhead K, Rao N, Roy CN, Andrews NC, Nemeth E, Follenzi A, An X, Mohandas N, Ginzburg Y, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S.

J Clin Invest. 2010 Dec;120(12):4466-77. doi: 10.1172/JCI41717.

6.

Protein quality control during erythropoiesis and hemoglobin synthesis.

Khandros E, Weiss MJ.

Hematol Oncol Clin North Am. 2010 Dec;24(6):1071-88. doi: 10.1016/j.hoc.2010.08.013. Review.

7.

Transferrin therapy ameliorates disease in beta-thalassemic mice.

Li H, Rybicki AC, Suzuka SM, von Bonsdorff L, Breuer W, Hall CB, Cabantchik ZI, Bouhassira EE, Fabry ME, Ginzburg YZ.

Nat Med. 2010 Feb;16(2):177-82. doi: 10.1038/nm.2073.

PMID:
20098432
8.

Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia.

Libani IV, Guy EC, Melchiori L, Schiro R, Ramos P, Breda L, Scholzen T, Chadburn A, Liu Y, Kernbach M, Baron-Lühr B, Porotto M, de Sousa M, Rachmilewitz EA, Hood JD, Cappellini MD, Giardina PJ, Grady RW, Gerdes J, Rivella S.

Blood. 2008 Aug 1;112(3):875-85. doi: 10.1182/blood-2007-12-126938.

9.

Inclusions of hemoglobin erythroblasts and erythrocytes of thalassemia.

FESSAS P.

Blood. 1963 Jan;21:21-32. No abstract available.

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