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Items: 1 to 20 of 44


The calcium-sensing receptor-dependent regulation of cell-cell adhesion and keratinocyte differentiation requires Rho and filamin A.

Tu CL, Chang W, Bikle DD.

J Invest Dermatol. 2011 May;131(5):1119-28. doi: 10.1038/jid.2010.414. Epub 2011 Jan 6.


Darier disease : a disease model of impaired calcium homeostasis in the skin.

Savignac M, Edir A, Simon M, Hovnanian A.

Biochim Biophys Acta. 2011 May;1813(5):1111-7. doi: 10.1016/j.bbamcr.2010.12.006. Epub 2010 Dec 15. Review.


Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation.

Oda Y, Uchida Y, Moradian S, Crumrine D, Elias PM, Bikle DD.

J Invest Dermatol. 2009 Jun;129(6):1367-78. doi: 10.1038/jid.2008.380. Epub 2008 Dec 4.


The extracellular calcium-sensing receptor (CaSR) is a critical modulator of skeletal development.

Chang W, Tu C, Chen TH, Bikle D, Shoback D.

Sci Signal. 2008 Sep 2;1(35):ra1. doi: 10.1126/scisignal.1159945.


Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers.

Aberg KM, Man MQ, Gallo RL, Ganz T, Crumrine D, Brown BE, Choi EH, Kim DK, Schröder JM, Feingold KR, Elias PM.

J Invest Dermatol. 2008 Apr;128(4):917-25. Epub 2007 Oct 18.


The skin barrier as an innate immune element.

Elias PM.

Semin Immunopathol. 2007 Apr;29(1):3-14. Review.


Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism.

Schauber J, Dorschner RA, Coda AB, Büchau AS, Liu PT, Kiken D, Helfrich YR, Kang S, Elalieh HZ, Steinmeyer A, Zügel U, Bikle DD, Modlin RL, Gallo RL.

J Clin Invest. 2007 Mar;117(3):803-11. Epub 2007 Feb 8.


The role of the calcium sensing receptor in regulating intracellular calcium handling in human epidermal keratinocytes.

Tu CL, Chang W, Bikle DD.

J Invest Dermatol. 2007 May;127(5):1074-83. Epub 2006 Nov 23.


Epidermal sphingolipids: metabolism, function, and roles in skin disorders.

Holleran WM, Takagi Y, Uchida Y.

FEBS Lett. 2006 Oct 9;580(23):5456-66. Epub 2006 Sep 1. Review.


Expression and functional assessment of an alternatively spliced extracellular Ca2+-sensing receptor in growth plate chondrocytes.

Rodriguez L, Tu C, Cheng Z, Chen TH, Bikle D, Shoback D, Chang W.

Endocrinology. 2005 Dec;146(12):5294-303. Epub 2005 Sep 15.


Vitamin D induces the antimicrobial protein hCAP18 in human skin.

Weber G, Heilborn JD, Chamorro Jimenez CI, Hammarsjo A, Törmä H, Stahle M.

J Invest Dermatol. 2005 May;124(5):1080-2. No abstract available.


25 Hydroxyvitamin D 1 alpha-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis.

Bikle DD, Chang S, Crumrine D, Elalieh H, Man MQ, Choi EH, Dardenne O, Xie Z, Arnaud RS, Feingold K, Elias PM.

J Invest Dermatol. 2004 Apr;122(4):984-92.


Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores.

Behne MJ, Tu CL, Aronchik I, Epstein E, Bench G, Bikle DD, Pozzan T, Mauro TM.

J Invest Dermatol. 2003 Oct;121(4):688-94.


Epidermal expression of the full-length extracellular calcium-sensing receptor is required for normal keratinocyte differentiation.

Komuves L, Oda Y, Tu CL, Chang WH, Ho-Pao CL, Mauro T, Bikle DD.

J Cell Physiol. 2002 Jul;192(1):45-54.


Coordinate regulation of epidermal differentiation and barrier homeostasis.

Elias PM, Feingold KR.

Skin Pharmacol Appl Skin Physiol. 2001;14 Suppl 1:28-34. Review. No abstract available.


The extracellular calcium-sensing receptor is required for calcium-induced differentiation in human keratinocytes.

Tu CL, Chang W, Bikle DD.

J Biol Chem. 2001 Nov 2;276(44):41079-85. Epub 2001 Aug 10.


Extracellular calcium sensing and extracellular calcium signaling.

Brown EM, MacLeod RJ.

Physiol Rev. 2001 Jan;81(1):239-297. Review.


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