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Items: 1 to 20 of 41


Manipulation of the recipient retinal environment by ectopic expression of neurotrophic growth factors can improve transplanted photoreceptor integration and survival.

West EL, Pearson RA, Duran Y, Gonzalez-Cordero A, MacLaren RE, Smith AJ, Sowden JC, Ali RR.

Cell Transplant. 2012;21(5):871-87. doi: 10.3727/096368911X623871. Epub 2012 Feb 2.


Effective transplantation of photoreceptor precursor cells selected via cell surface antigen expression.

Lakowski J, Han YT, Pearson RA, Gonzalez-Cordero A, West EL, Gualdoni S, Barber AC, Hubank M, Ali RR, Sowden JC.

Stem Cells. 2011 Sep;29(9):1391-404. doi: 10.1002/stem.694.


Intravenous administration of AAV2/9 to the fetal and neonatal mouse leads to differential targeting of CNS cell types and extensive transduction of the nervous system.

Rahim AA, Wong AM, Hoefer K, Buckley SM, Mattar CN, Cheng SH, Chan JK, Cooper JD, Waddington SN.

FASEB J. 2011 Oct;25(10):3505-18. doi: 10.1096/fj.11-182311. Epub 2011 Jul 11.


Self-organizing optic-cup morphogenesis in three-dimensional culture.

Eiraku M, Takata N, Ishibashi H, Kawada M, Sakakura E, Okuda S, Sekiguchi K, Adachi T, Sasai Y.

Nature. 2011 Apr 7;472(7341):51-6. doi: 10.1038/nature09941.


Differential expression of neuronal genes in Müller glia in two- and three-dimensional cultures.

Phillips MJ, Otteson DC.

Invest Ophthalmol Vis Sci. 2011 Mar 14;52(3):1439-49. doi: 10.1167/iovs.10-6400. Print 2011 Mar.


Cone and rod photoreceptor transplantation in models of the childhood retinopathy Leber congenital amaurosis using flow-sorted Crx-positive donor cells.

Lakowski J, Baron M, Bainbridge J, Barber AC, Pearson RA, Ali RR, Sowden JC.

Hum Mol Genet. 2010 Dec 1;19(23):4545-59. doi: 10.1093/hmg/ddq378. Epub 2010 Sep 21.


Long-term survival of photoreceptors transplanted into the adult murine neural retina requires immune modulation.

West EL, Pearson RA, Barker SE, Luhmann UF, Maclaren RE, Barber AC, Duran Y, Smith AJ, Sowden JC, Ali RR.

Stem Cells. 2010 Nov;28(11):1997-2007. doi: 10.1002/stem.520.


Generation, purification and transplantation of photoreceptors derived from human induced pluripotent stem cells.

Lamba DA, McUsic A, Hirata RK, Wang PR, Russell D, Reh TA.

PLoS One. 2010 Jan 20;5(1):e8763. doi: 10.1371/journal.pone.0008763.


Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina.

Pearson RA, Barber AC, West EL, MacLaren RE, Duran Y, Bainbridge JW, Sowden JC, Ali RR.

Cell Transplant. 2010;19(4):487-503. doi: 10.3727/096368909X486057. Epub 2010 Jan 20.


Modeling early retinal development with human embryonic and induced pluripotent stem cells.

Meyer JS, Shearer RL, Capowski EE, Wright LS, Wallace KA, McMillan EL, Zhang SC, Gamm DM.

Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16698-703. doi: 10.1073/pnas.0905245106. Epub 2009 Aug 25.


Adeno-associated virus serotype-9 efficiently transduces the retinal outer plexiform layer.

Lei B, Zhang K, Yue Y, Ghosh A, Duan D.

Mol Vis. 2009 Jul 17;15:1374-82.


Generation of retinal cells from mouse and human induced pluripotent stem cells.

Hirami Y, Osakada F, Takahashi K, Okita K, Yamanaka S, Ikeda H, Yoshimura N, Takahashi M.

Neurosci Lett. 2009 Jul 24;458(3):126-31. doi: 10.1016/j.neulet.2009.04.035. Epub 2009 Apr 18.


Transplantation of human embryonic stem cell-derived photoreceptors restores some visual function in Crx-deficient mice.

Lamba DA, Gust J, Reh TA.

Cell Stem Cell. 2009 Jan 9;4(1):73-9. doi: 10.1016/j.stem.2008.10.015.


Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation.

Wataya T, Ando S, Muguruma K, Ikeda H, Watanabe K, Eiraku M, Kawada M, Takahashi J, Hashimoto N, Sasai Y.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11796-801. doi: 10.1073/pnas.0803078105. Epub 2008 Aug 12.


Fate of embryonic stem cell derivatives implanted into the vitreous of a slow retinal degenerative mouse model.

Chaudhry GR, Fecek C, Lai MM, Wu WC, Chang M, Vasquez A, Pasierb M, Trese MT.

Stem Cells Dev. 2009 Mar;18(2):247-58. doi: 10.1089/scd.2008.0057.


Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors.

West EL, Pearson RA, Tschernutter M, Sowden JC, MacLaren RE, Ali RR.

Exp Eye Res. 2008 Apr;86(4):601-11. doi: 10.1016/j.exer.2008.01.004. Epub 2008 Jan 12.


Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells.

Osakada F, Ikeda H, Mandai M, Wataya T, Watanabe K, Yoshimura N, Akaike A, Sasai Y, Takahashi M.

Nat Biotechnol. 2008 Feb;26(2):215-24. doi: 10.1038/nbt1384. Epub 2008 Feb 3. Erratum in: Nat Biotechnol. 2008 Mar;26(3):352. Akaike, Akiori [corrected to Akaike, Akinori].


Reprogramming of human somatic cells to pluripotency with defined factors.

Park IH, Zhao R, West JA, Yabuuchi A, Huo H, Ince TA, Lerou PH, Lensch MW, Daley GQ.

Nature. 2008 Jan 10;451(7175):141-6. Epub 2007 Dec 23.


Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S.

Cell. 2007 Nov 30;131(5):861-72.


Regulation of photoreceptor gene expression by Crx-associated transcription factor network.

Hennig AK, Peng GH, Chen S.

Brain Res. 2008 Feb 4;1192:114-33. Epub 2007 Jun 30. Review.

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