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Items: 1 to 20 of 81

1.

Differences between the pattern of developmental abnormalities in autism associated with duplications 15q11.2-q13 and idiopathic autism.

Wegiel J, Schanen NC, Cook EH, Sigman M, Brown WT, Kuchna I, Nowicki K, Wegiel J, Imaki H, Ma SY, Marchi E, Wierzba-Bobrowicz T, Chauhan A, Chauhan V, Cohen IL, London E, Flory M, Lach B, Wisniewski T.

J Neuropathol Exp Neurol. 2012 May;71(5):382-97. doi: 10.1097/NEN.0b013e318251f537.

2.

Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO mice.

Westmark CJ, Westmark PR, O'Riordan KJ, Ray BC, Hervey CM, Salamat MS, Abozeid SH, Stein KM, Stodola LA, Tranfaglia M, Burger C, Berry-Kravis EM, Malter JS.

PLoS One. 2011;6(10):e26549. doi: 10.1371/journal.pone.0026549. Epub 2011 Oct 26.

3.

Increased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarker.

Ray B, Long JM, Sokol DK, Lahiri DK.

PLoS One. 2011;6(6):e20405. doi: 10.1371/journal.pone.0020405. Epub 2011 Jun 22.

4.

Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration.

Winton MJ, Lee EB, Sun E, Wong MM, Leight S, Zhang B, Trojanowski JQ, Lee VM.

J Neurosci. 2011 May 25;31(21):7691-9. doi: 10.1523/JNEUROSCI.6637-10.2011. Retraction in: J Neurosci. 2015 Feb 25;35(8):3724.

5.

Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links.

Sokol DK, Maloney B, Long JM, Ray B, Lahiri DK.

Neurology. 2011 Apr 12;76(15):1344-52. doi: 10.1212/WNL.0b013e3182166dc7. Review.

6.

High-affinity rabbit monoclonal antibodies specific for amyloid peptides amyloid-β40 and amyloid-β42.

Miller DL, Potempska A, Wegiel J, Mehta PD.

J Alzheimers Dis. 2011;23(2):293-305. doi: 10.3233/JAD-2010-101341.

PMID:
21116049
7.

Intracellular accumulation of amyloid-Beta - a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease.

Bayer TA, Wirths O.

Front Aging Neurosci. 2010 Mar 10;2:8. doi: 10.3389/fnagi.2010.00008. eCollection 2010.

8.

Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease.

Gouras GK, Tampellini D, Takahashi RH, Capetillo-Zarate E.

Acta Neuropathol. 2010 May;119(5):523-41. doi: 10.1007/s00401-010-0679-9. Epub 2010 Mar 31. Review.

9.

The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes.

Wegiel J, Kuchna I, Nowicki K, Imaki H, Wegiel J, Marchi E, Ma SY, Chauhan A, Chauhan V, Bobrowicz TW, de Leon M, Louis LA, Cohen IL, London E, Brown WT, Wisniewski T.

Acta Neuropathol. 2010 Jun;119(6):755-70. doi: 10.1007/s00401-010-0655-4. Epub 2010 Mar 3.

10.

MPEP reduces seizure severity in Fmr-1 KO mice over expressing human Abeta.

Westmark CJ, Westmark PR, Malter JS.

Int J Clin Exp Pathol. 2009 Oct 10;3(1):56-68.

11.

Cathepsin D and apoptosis related proteins are elevated in the brain of autistic subjects.

Sheikh AM, Li X, Wen G, Tauqeer Z, Brown WT, Malik M.

Neuroscience. 2010 Jan 20;165(2):363-70. doi: 10.1016/j.neuroscience.2009.10.035.

PMID:
19854241
12.

Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury.

McKee AC, Cantu RC, Nowinski CJ, Hedley-Whyte ET, Gavett BE, Budson AE, Santini VE, Lee HS, Kubilus CA, Stern RA.

J Neuropathol Exp Neurol. 2009 Jul;68(7):709-35. doi: 10.1097/NEN.0b013e3181a9d503. Review.

13.

Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta.

Pigino G, Morfini G, Atagi Y, Deshpande A, Yu C, Jungbauer L, LaDu M, Busciglio J, Brady S.

Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5907-12. doi: 10.1073/pnas.0901229106. Epub 2009 Mar 24.

14.

Aminopeptidase A contributes to the N-terminal truncation of amyloid beta-peptide.

Sevalle J, Amoyel A, Robert P, Fournié-Zaluski MC, Roques B, Checler F.

J Neurochem. 2009 Apr;109(1):248-56. doi: 10.1111/j.1471-4159.2009.05950.x. Epub 2009 Feb 23.

15.

Peripheral biomarkers in Autism: secreted amyloid precursor protein-alpha as a probable key player in early diagnosis.

Bailey AR, Giunta BN, Obregon D, Nikolic WV, Tian J, Sanberg CD, Sutton DT, Tan J.

Int J Clin Exp Med. 2008;1(4):338-44. Epub 2008 Oct 15.

16.

Seizure susceptibility and mortality in mice that over-express amyloid precursor protein.

Westmark CJ, Westmark PR, Beard AM, Hildebrandt SM, Malter JS.

Int J Clin Exp Pathol. 2008 Jan 1;1(2):157-68.

17.

Association of increased cortical soluble abeta42 levels with diffuse plaques after severe brain injury in humans.

DeKosky ST, Abrahamson EE, Ciallella JR, Paljug WR, Wisniewski SR, Clark RS, Ikonomovic MD.

Arch Neurol. 2007 Apr;64(4):541-4.

PMID:
17420316
18.
19.

Intraneuronal Abeta immunoreactivity is not a predictor of brain amyloidosis-beta or neurofibrillary degeneration.

Wegiel J, Kuchna I, Nowicki K, Frackowiak J, Mazur-Kolecka B, Imaki H, Wegiel J, Mehta PD, Silverman WP, Reisberg B, Deleon M, Wisniewski T, Pirttilla T, Frey H, Lehtimäki T, Kivimäki T, Visser FE, Kamphorst W, Potempska A, Bolton D, Currie JR, Miller DL.

Acta Neuropathol. 2007 Apr;113(4):389-402. Epub 2007 Jan 20.

20.

High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression.

Sokol DK, Chen D, Farlow MR, Dunn DW, Maloney B, Zimmer JA, Lahiri DK.

J Child Neurol. 2006 Jun;21(6):444-9.

PMID:
16948926

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