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Items: 1 to 20 of 74


Sir-2.1 modulates 'calorie-restriction-mediated' prevention of neurodegeneration in Caenorhabditis elegans: implications for Parkinson's disease.

Jadiya P, Chatterjee M, Sammi SR, Kaur S, Palit G, Nazir A.

Biochem Biophys Res Commun. 2011 Sep 23;413(2):306-10. doi: 10.1016/j.bbrc.2011.08.092. Epub 2011 Aug 26.


Identification of mutations that delay somatic or reproductive aging of Caenorhabditis elegans.

Hughes SE, Huang C, Kornfeld K.

Genetics. 2011 Sep;189(1):341-56. doi: 10.1534/genetics.111.130450. Epub 2011 Jul 12.


Spontaneous age-related neurite branching in Caenorhabditis elegans.

Tank EM, Rodgers KE, Kenyon C.

J Neurosci. 2011 Jun 22;31(25):9279-88. doi: 10.1523/JNEUROSCI.6606-10.2011.


Genetic analysis of age-dependent defects of the Caenorhabditis elegans touch receptor neurons.

Pan CL, Peng CY, Chen CH, McIntire S.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9274-9. doi: 10.1073/pnas.1011711108. Epub 2011 May 12.


PDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolism.

Narasimhan SD, Yen K, Bansal A, Kwon ES, Padmanabhan S, Tissenbaum HA.

PLoS Genet. 2011 Apr;7(4):e1001377. doi: 10.1371/journal.pgen.1001377. Epub 2011 Apr 21.


Loss of intestinal nuclei and intestinal integrity in aging C. elegans.

McGee MD, Weber D, Day N, Vitelli C, Crippen D, Herndon LA, Hall DH, Melov S.

Aging Cell. 2011 Aug;10(4):699-710. doi: 10.1111/j.1474-9726.2011.00713.x. Epub 2011 May 25.


Single-gene mutations and healthy ageing in mammals.

Bartke A.

Philos Trans R Soc Lond B Biol Sci. 2011 Jan 12;366(1561):28-34. doi: 10.1098/rstb.2010.0281. Review.


The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing.

Kenyon C.

Philos Trans R Soc Lond B Biol Sci. 2011 Jan 12;366(1561):9-16. doi: 10.1098/rstb.2010.0276. Review.


TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance.

Luo S, Kleemann GA, Ashraf JM, Shaw WM, Murphy CT.

Cell. 2010 Oct 15;143(2):299-312. doi: 10.1016/j.cell.2010.09.013.


DAF-16/Forkhead box O transcription factor: many paths to a single Fork(head) in the road.

Yen K, Narasimhan SD, Tissenbaum HA.

Antioxid Redox Signal. 2011 Feb 15;14(4):623-34. doi: 10.1089/ars.2010.3490. Epub 2010 Nov 30.


Novel EGF pathway regulators modulate C. elegans healthspan and lifespan via EGF receptor, PLC-gamma, and IP3R activation.

Iwasa H, Yu S, Xue J, Driscoll M.

Aging Cell. 2010 Aug;9(4):490-505. doi: 10.1111/j.1474-9726.2010.00575.x. Epub 2010 May 22.


The genetics of ageing.

Kenyon CJ.

Nature. 2010 Mar 25;464(7288):504-12. doi: 10.1038/nature08980. Review. Erratum in: Nature. 2010 Sep 30;467(7315):622.


Advanced glycation end products as biomarkers and gerontotoxins - A basis to explore methylglyoxal-lowering agents for Alzheimer's disease?

Krautwald M, Münch G.

Exp Gerontol. 2010 Oct;45(10):744-51. doi: 10.1016/j.exger.2010.03.001. Epub 2010 Mar 6. Review.


Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO.

Landis JN, Murphy CT.

Dev Dyn. 2010 May;239(5):1405-12. doi: 10.1002/dvdy.22244. Review.


Temporal requirements of insulin/IGF-1 signaling for proteotoxicity protection.

Cohen E, Du D, Joyce D, Kapernick EA, Volovik Y, Kelly JW, Dillin A.

Aging Cell. 2010 Apr;9(2):126-34. doi: 10.1111/j.1474-9726.2009.00541.x. Epub 2009 Dec 11.


Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations.

Li Y, Wang WJ, Cao H, Lu J, Wu C, Hu FY, Guo J, Zhao L, Yang F, Zhang YX, Li W, Zheng GY, Cui H, Chen X, Zhu Z, He H, Dong B, Mo X, Zeng Y, Tian XL.

Hum Mol Genet. 2009 Dec 15;18(24):4897-904. doi: 10.1093/hmg/ddp459. Epub 2009 Sep 29.


Converging pathways in lifespan regulation.

Narasimhan SD, Yen K, Tissenbaum HA.

Curr Biol. 2009 Aug 11;19(15):R657-66. doi: 10.1016/j.cub.2009.06.013. Review.


Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study.

Anselmi CV, Malovini A, Roncarati R, Novelli V, Villa F, Condorelli G, Bellazzi R, Puca AA.

Rejuvenation Res. 2009 Apr;12(2):95-104. doi: 10.1089/rej.2008.0827.

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