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Items: 1 to 20 of 28

1.

The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.

Sharma AK, Kline CL, Berg A, Amin S, Irby RB.

Clin Cancer Res. 2011 Jul 1;17(13):4474-83. doi: 10.1158/1078-0432.CCR-10-2370. Epub 2011 May 9.

2.

Induction of autophagy in temozolomide treated malignant gliomas.

Natsumeda M, Aoki H, Miyahara H, Yajima N, Uzuka T, Toyoshima Y, Kakita A, Takahashi H, Fujii Y.

Neuropathology. 2011 Oct;31(5):486-93. doi: 10.1111/j.1440-1789.2010.01197.x. Epub 2011 Jan 27.

PMID:
21269334
3.

Melanoma chemoprevention in skin reconstructs and mouse xenografts using isoselenocyanate-4.

Nguyen N, Sharma A, Nguyen N, Sharma AK, Desai D, Huh SJ, Amin S, Meyers C, Robertson GP.

Cancer Prev Res (Phila). 2011 Feb;4(2):248-58. doi: 10.1158/1940-6207.CAPR-10-0106. Epub 2010 Nov 19.

4.

Synthesis and evaluation of the anti-inflammatory properties of selenium-derivatives of celecoxib.

Desai D, Kaushal N, Gandhi UH, Arner RJ, D'Souza C, Chen G, Vunta H, El-Bayoumy K, Amin S, Prabhu KS.

Chem Biol Interact. 2010 Dec 5;188(3):446-56. doi: 10.1016/j.cbi.2010.09.021. Epub 2010 Sep 29.

5.

Activation of AMP-activated protein kinase by temozolomide contributes to apoptosis in glioblastoma cells via p53 activation and mTORC1 inhibition.

Zhang WB, Wang Z, Shu F, Jin YH, Liu HY, Wang QJ, Yang Y.

J Biol Chem. 2010 Dec 24;285(52):40461-71. doi: 10.1074/jbc.M110.164046. Epub 2010 Sep 29.

6.

Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis.

Niu TK, Cheng Y, Ren X, Yang JM.

FEBS Lett. 2010 Aug 20;584(16):3519-24. doi: 10.1016/j.febslet.2010.07.018. Epub 2010 Jul 16.

7.

Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer.

Dalby KN, Tekedereli I, Lopez-Berestein G, Ozpolat B.

Autophagy. 2010 Apr;6(3):322-9. Epub 2010 Apr 26. Review.

8.

SelSA, selenium analogs of SAHA as potent histone deacetylase inhibitors.

Desai D, Salli U, Vrana KE, Amin S.

Bioorg Med Chem Lett. 2010 Mar 15;20(6):2044-7. doi: 10.1016/j.bmcl.2009.07.068. Epub 2009 Jul 17.

9.

Synthesis and antitumor properties of selenocoxib-1 against rat prostate adenocarcinoma cells.

Desai D, Sinha I, Null K, Wolter W, Suckow MA, King T, Amin S, Sinha R.

Int J Cancer. 2010 Jul 1;127(1):230-8. doi: 10.1002/ijc.25033.

10.

Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells.

Yoo BH, Wu X, Li Y, Haniff M, Sasazuki T, Shirasawa S, Eskelinen EL, Rosen KV.

J Biol Chem. 2010 Feb 19;285(8):5438-49. doi: 10.1074/jbc.M109.046789. Epub 2009 Sep 24.

11.

Targeting Akt3 signaling in malignant melanoma using isoselenocyanates.

Sharma A, Sharma AK, Madhunapantula SV, Desai D, Huh SJ, Mosca P, Amin S, Robertson GP.

Clin Cancer Res. 2009 Mar 1;15(5):1674-85. doi: 10.1158/1078-0432.CCR-08-2214. Epub 2009 Feb 10.

12.

Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.

Naumann SC, Roos WP, Jöst E, Belohlavek C, Lennerz V, Schmidt CW, Christmann M, Kaina B.

Br J Cancer. 2009 Jan 27;100(2):322-33. doi: 10.1038/sj.bjc.6604856. Epub 2009 Jan 6.

13.

Synthesis and anticancer activity comparison of phenylalkyl isoselenocyanates with corresponding naturally occurring and synthetic isothiocyanates.

Sharma AK, Sharma A, Desai D, Madhunapantula SV, Huh SJ, Robertson GP, Amin S.

J Med Chem. 2008 Dec 25;51(24):7820-6. doi: 10.1021/jm800993r.

14.

Differential sensitivity of various human tumour-derived cell types to apoptosis by organic derivatives of selenium.

Jariwalla RJ, Gangapurkar B, Nakamura D.

Br J Nutr. 2009 Jan;101(2):182-9. doi: 10.1017/S0007114508998305. Epub 2008 Jun 13.

PMID:
18549510
15.

Autophagy: an emerging target for cancer therapy.

Høyer-Hansen M, Jäättelä M.

Autophagy. 2008 Jul;4(5):574-80. Epub 2008 Mar 17. Review.

PMID:
18362515
16.

Phase II trial of arsenic trioxide and ascorbic acid with temozolomide in patients with metastatic melanoma with or without central nervous system metastases.

Bael TE, Peterson BL, Gollob JA.

Melanoma Res. 2008 Apr;18(2):147-51. doi: 10.1097/CMR.0b013e3282f2a7ae.

PMID:
18337652
17.

MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.

Kaina B, Christmann M, Naumann S, Roos WP.

DNA Repair (Amst). 2007 Aug 1;6(8):1079-99. Epub 2007 May 7. Review.

PMID:
17485253
18.

Stress and mTORture signaling.

Reiling JH, Sabatini DM.

Oncogene. 2006 Oct 16;25(48):6373-83. Review.

PMID:
17041623
19.

Partial Beclin 1 silencing aggravates doxorubicin- and Fas-induced apoptosis in HepG2 cells.

Daniel F, Legrand A, Pessayre D, Vadrot N, Descatoire V, Bernuau D.

World J Gastroenterol. 2006 May 14;12(18):2895-900.

20.

Selenium in cancer prevention: a review of the evidence and mechanism of action.

Rayman MP.

Proc Nutr Soc. 2005 Nov;64(4):527-42. Review.

PMID:
16313696

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