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Down-regulation of TSG101 by small interfering RNA inhibits the proliferation of breast cancer cells through the MAPK/ERK signal pathway.

Zhang Y, Song M, Cui ZS, Li CY, Xue XX, Yu M, Lu Y, Zhang SY, Wang EH, Wen YY.

Histol Histopathol. 2011 Jan;26(1):87-94. doi: 10.14670/HH-26.87.


Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions.

Tu C, Ortega-Cava CF, Winograd P, Stanton MJ, Reddi AL, Dodge I, Arya R, Dimri M, Clubb RJ, Naramura M, Wagner KU, Band V, Band H.

Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16107-12. doi: 10.1073/pnas.1009471107. Epub 2010 Aug 30.


HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy.

Lee JY, Koga H, Kawaguchi Y, Tang W, Wong E, Gao YS, Pandey UB, Kaushik S, Tresse E, Lu J, Taylor JP, Cuervo AM, Yao TP.

EMBO J. 2010 Mar 3;29(5):969-80. doi: 10.1038/emboj.2009.405. Epub 2010 Jan 14.


TSG101, identified by screening a cancer cDNA library and soft agar assay, promotes cell proliferation in human lung cancer.

Liu F, Yu Y, Jin Y, Fu S.

Mol Biol Rep. 2010 Jul;37(6):2829-38. doi: 10.1007/s11033-009-9835-5. Epub 2009 Sep 29.


Overexpression of WNT2 and TSG101 genes in colorectal carcinoma.

Ma XR, Edmund Sim UH, Pauline B, Patricia L, Rahman J.

Trop Biomed. 2008 Apr;25(1):46-57.


Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease.

Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A.

J Cell Biol. 2007 Nov 5;179(3):485-500.


Up-regulation of tumor susceptibility gene 101 conveys poor prognosis through suppression of p21 expression in ovarian cancer.

Young TW, Rosen DG, Mei FC, Li N, Liu J, Wang XF, Cheng X.

Clin Cancer Res. 2007 Jul 1;13(13):3848-54.


Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery.

Carlton JG, Martin-Serrano J.

Science. 2007 Jun 29;316(5833):1908-12. Epub 2007 Jun 7.


Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation.

Razi M, Futter CE.

Mol Biol Cell. 2006 Aug;17(8):3469-83. Epub 2006 May 17.


Depletion of TSG101 forms a mammalian "Class E" compartment: a multicisternal early endosome with multiple sorting defects.

Doyotte A, Russell MR, Hopkins CR, Woodman PG.

J Cell Sci. 2005 Jul 15;118(Pt 14):3003-17.


Subversion of cellular autophagosomal machinery by RNA viruses.

Jackson WT, Giddings TH Jr, Taylor MP, Mulinyawe S, Rabinovitch M, Kopito RR, Kirkegaard K.

PLoS Biol. 2005 May;3(5):e156. Epub 2005 Apr 26.


Inhibition of macroautophagy triggers apoptosis.

Boya P, González-Polo RA, Casares N, Perfettini JL, Dessen P, Larochette N, Métivier D, Meley D, Souquere S, Yoshimori T, Pierron G, Codogno P, Kroemer G.

Mol Cell Biol. 2005 Feb;25(3):1025-40.


Cell cycle arrest and cell death are controlled by p53-dependent and p53-independent mechanisms in Tsg101-deficient cells.

Carstens MJ, Krempler A, Triplett AA, Van Lohuizen M, Wagner KU.

J Biol Chem. 2004 Aug 20;279(34):35984-94. Epub 2004 Jun 21.


Reduction of TSG101 protein has a negative impact on tumor cell growth.

Zhu G, Gilchrist R, Borley N, Chng HW, Morgan M, Marshall JF, Camplejohn RS, Muir GH, Hart IR.

Int J Cancer. 2004 Apr 20;109(4):541-7.


TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation.

Lu Q, Hope LW, Brasch M, Reinhard C, Cohen SN.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7626-31. Epub 2003 Jun 11.


Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues.

Wagner KU, Krempler A, Qi Y, Park K, Henry MD, Triplett AA, Riedlinger G, Rucker III EB, Hennighausen L.

Mol Cell Biol. 2003 Jan;23(1):150-62.


Targeted deletion of the Tsg101 gene results in cell cycle arrest at G1/S and p53-independent cell death.

Krempler A, Henry MD, Triplett AA, Wagner KU.

J Biol Chem. 2002 Nov 8;277(45):43216-23. Epub 2002 Aug 29.


Overexpression of tumor susceptibility gene TSG101 in human papillary thyroid carcinomas.

Liu RT, Huang CC, You HL, Chou FF, Hu CC, Chao FP, Chen CM, Cheng JT.

Oncogene. 2002 Jul 18;21(31):4830-7.


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