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Items: 1 to 20 of 57

1.

Human mediator subunit MED26 functions as a docking site for transcription elongation factors.

Takahashi H, Parmely TJ, Sato S, Tomomori-Sato C, Banks CA, Kong SE, Szutorisz H, Swanson SK, Martin-Brown S, Washburn MP, Florens L, Seidel CW, Lin C, Smith ER, Shilatifard A, Conaway RC, Conaway JW.

Cell. 2011 Jul 8;146(1):92-104. doi: 10.1016/j.cell.2011.06.005.

2.

Galactose induction of the GAL1 gene requires conditional degradation of the Mig2 repressor.

Lim MK, Siew WL, Zhao J, Tay YC, Ang E, Lehming N.

Biochem J. 2011 May 1;435(3):641-9. doi: 10.1042/BJ20102034.

PMID:
21323640
3.

The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation.

Malik S, Roeder RG.

Nat Rev Genet. 2010 Nov;11(11):761-72. doi: 10.1038/nrg2901. Epub 2010 Oct 13. Review.

4.

Transcriptional activation requires protection of the TATA-binding protein Tbp1 by the ubiquitin-specific protease Ubp3.

Chew BS, Siew WL, Xiao B, Lehming N.

Biochem J. 2010 Nov 1;431(3):391-9. doi: 10.1042/BJ20101152.

PMID:
20738257
5.

Mediator and cohesin connect gene expression and chromatin architecture.

Kagey MH, Newman JJ, Bilodeau S, Zhan Y, Orlando DA, van Berkum NL, Ebmeier CC, Goossens J, Rahl PB, Levine SS, Taatjes DJ, Dekker J, Young RA.

Nature. 2010 Sep 23;467(7314):430-5. doi: 10.1038/nature09380. Epub 2010 Aug 18. Erratum in: Nature. 2011 Apr 14;472(7342):247.

6.

p53 activates transcription by directing structural shifts in Mediator.

Meyer KD, Lin SC, Bernecky C, Gao Y, Taatjes DJ.

Nat Struct Mol Biol. 2010 Jun;17(6):753-60. doi: 10.1038/nsmb.1816. Epub 2010 May 9.

7.

A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding.

Floer M, Wang X, Prabhu V, Berrozpe G, Narayan S, Spagna D, Alvarez D, Kendall J, Krasnitz A, Stepansky A, Hicks J, Bryant GO, Ptashne M.

Cell. 2010 Apr 30;141(3):407-18. doi: 10.1016/j.cell.2010.03.048.

8.

Proteolytic instability and the action of nonclassical transcriptional activators.

Wang X, Muratani M, Tansey WP, Ptashne M.

Curr Biol. 2010 May 11;20(9):868-71. doi: 10.1016/j.cub.2010.03.029. Epub 2010 Apr 22.

9.

The human Mediator complex: a versatile, genome-wide regulator of transcription.

Taatjes DJ.

Trends Biochem Sci. 2010 Jun;35(6):315-22. doi: 10.1016/j.tibs.2010.02.004. Epub 2010 Mar 17. Review.

10.

Alterations in the interaction between GAL4 and GAL80 effect regulation of the yeast GAL regulon mediated by the F box protein Dsg1.

Li Y, Chen G, Liu W.

Curr Microbiol. 2010 Sep;61(3):210-6. doi: 10.1007/s00284-010-9598-1. Epub 2010 Feb 5.

PMID:
20135317
11.

The hydrophobic patch of ubiquitin is required to protect transactivator-promoter complexes from destabilization by the proteasomal ATPases.

Archer CT, Kodadek T.

Nucleic Acids Res. 2010 Jan;38(3):789-96. doi: 10.1093/nar/gkp1066. Epub 2009 Nov 25.

12.

Gal4 turnover and transcription activation.

Collins GA, Lipford JR, Deshaies RJ, Tansey WP.

Nature. 2009 Oct 8;461(7265):E7; discussion E8. doi: 10.1038/nature08406.

13.

Gene activation by dissociation of an inhibitor from a transcriptional activation domain.

Jiang F, Frey BR, Evans ML, Friel JC, Hopper JE.

Mol Cell Biol. 2009 Oct;29(20):5604-10. doi: 10.1128/MCB.00632-09. Epub 2009 Aug 3.

14.

Nucleosome positioning and gene regulation: advances through genomics.

Jiang C, Pugh BF.

Nat Rev Genet. 2009 Mar;10(3):161-72. doi: 10.1038/nrg2522. Review.

15.

Activator control of nucleosome occupancy in activation and repression of transcription.

Bryant GO, Prabhu V, Floer M, Wang X, Spagna D, Schreiber D, Ptashne M.

PLoS Biol. 2008 Dec 23;6(12):2928-39. doi: 10.1371/journal.pbio.0060317.

16.

Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation.

Ding N, Zhou H, Esteve PO, Chin HG, Kim S, Xu X, Joseph SM, Friez MJ, Schwartz CE, Pradhan S, Boyer TG.

Mol Cell. 2008 Aug 8;31(3):347-59. doi: 10.1016/j.molcel.2008.05.023.

17.

Activation domain-dependent monoubiquitylation of Gal4 protein is essential for promoter binding in vivo.

Archer CT, Delahodde A, Gonzalez F, Johnston SA, Kodadek T.

J Biol Chem. 2008 May 2;283(18):12614-23. doi: 10.1074/jbc.M801050200. Epub 2008 Mar 6.

18.

NADP regulates the yeast GAL induction system.

Kumar PR, Yu Y, Sternglanz R, Johnston SA, Joshua-Tor L.

Science. 2008 Feb 22;319(5866):1090-2. doi: 10.1126/science.1151903.

19.

Genetic evidence for sites of interaction between the Gal3 and Gal80 proteins of the Saccharomyces cerevisiae GAL gene switch.

Diep CQ, Tao X, Pilauri V, Losiewicz M, Blank TE, Hopper JE.

Genetics. 2008 Feb;178(2):725-36. doi: 10.1534/genetics.107.074799. Epub 2008 Feb 3.

20.

The N-end rule pathway is a sensor of heme.

Hu RG, Wang H, Xia Z, Varshavsky A.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):76-81. Epub 2007 Dec 27.

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