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Anesthetic-related neurotoxicity and the developing brain: shall we change practice?

Vutskits L.

Paediatr Drugs. 2012 Feb 1;14(1):13-21. doi: 10.2165/11592840-000000000-00000. Review.


Review article: Neurotoxicity of anesthetic drugs in the developing brain.

Stratmann G.

Anesth Analg. 2011 Nov;113(5):1170-9. doi: 10.1213/ANE.0b013e318232066c. Epub 2011 Sep 30. Review.


Anesthesia during surgical repair for congenital heart disease and the developing brain: neurotoxic or neuroprotective?

Wise-Faberowski L, Loepke A.

Paediatr Anaesth. 2011 May;21(5):554-9. doi: 10.1111/j.1460-9592.2011.03586.x. Review. No abstract available.


Elective delivery at less than 39 weeks.

Ashton DM.

Curr Opin Obstet Gynecol. 2010 Dec;22(6):506-10. doi: 10.1097/GCO.0b013e3283404eb4. Review.


Birth before 39 weeks' gestation is associated with worse outcomes in neonates with heart disease.

Costello JM, Polito A, Brown DW, McElrath TF, Graham DA, Thiagarajan RR, Bacha EA, Allan CK, Cohen JN, Laussen PC.

Pediatrics. 2010 Aug;126(2):277-84. doi: 10.1542/peds.2009-3640. Epub 2010 Jul 5.


Comparison of shunt types in the Norwood procedure for single-ventricle lesions.

Ohye RG, Sleeper LA, Mahony L, Newburger JW, Pearson GD, Lu M, Goldberg CS, Tabbutt S, Frommelt PC, Ghanayem NS, Laussen PC, Rhodes JF, Lewis AB, Mital S, Ravishankar C, Williams IA, Dunbar-Masterson C, Atz AM, Colan S, Minich LL, Pizarro C, Kanter KR, Jaggers J, Jacobs JP, Krawczeski CD, Pike N, McCrindle BW, Virzi L, Gaynor JW; Pediatric Heart Network Investigators..

N Engl J Med. 2010 May 27;362(21):1980-92. doi: 10.1056/NEJMoa0912461.


Brain volume and metabolism in fetuses with congenital heart disease: evaluation with quantitative magnetic resonance imaging and spectroscopy.

Limperopoulos C, Tworetzky W, McElhinney DB, Newburger JW, Brown DW, Robertson RL Jr, Guizard N, McGrath E, Geva J, Annese D, Dunbar-Masterson C, Trainor B, Laussen PC, du Plessis AJ.

Circulation. 2010 Jan 5;121(1):26-33. doi: 10.1161/CIRCULATIONAHA.109.865568. Epub 2009 Dec 21.


Brain immaturity is associated with brain injury before and after neonatal cardiac surgery with high-flow bypass and cerebral oxygenation monitoring.

Andropoulos DB, Hunter JV, Nelson DP, Stayer SA, Stark AR, McKenzie ED, Heinle JS, Graves DE, Fraser CD Jr.

J Thorac Cardiovasc Surg. 2010 Mar;139(3):543-56. doi: 10.1016/j.jtcvs.2009.08.022. Epub 2009 Nov 11.


The quest to optimize neurodevelopmental outcomes in neonatal arch reconstruction: the perfusion techniques we use and why we believe in them.

Ohye RG, Goldberg CS, Donohue J, Hirsch JC, Gaies M, Jacobs ML, Gurney JG; Michigan Congenital Heart Outcomes Research and Discovery Investigators..

J Thorac Cardiovasc Surg. 2009 Apr;137(4):803-6. doi: 10.1016/j.jtcvs.2008.10.046. No abstract available.


Brain maturation is delayed in infants with complex congenital heart defects.

Licht DJ, Shera DM, Clancy RR, Wernovsky G, Montenegro LM, Nicolson SC, Zimmerman RA, Spray TL, Gaynor JW, Vossough A.

J Thorac Cardiovasc Surg. 2009 Mar;137(3):529-36; discussion 536-7. doi: 10.1016/j.jtcvs.2008.10.025.


Design and rationale of a randomized trial comparing the Blalock-Taussig and right ventricle-pulmonary artery shunts in the Norwood procedure.

Ohye RG, Gaynor JW, Ghanayem NS, Goldberg CS, Laussen PC, Frommelt PC, Newburger JW, Pearson GD, Tabbutt S, Wernovsky G, Wruck LM, Atz AM, Colan SD, Jaggers J, McCrindle BW, Prakash A, Puchalski MD, Sleeper LA, Stylianou MP, Mahony L; Pediatric Heart Network Investigators..

J Thorac Cardiovasc Surg. 2008 Oct;136(4):968-75. doi: 10.1016/j.jtcvs.2008.01.013. Epub 2008 May 19.


Prenatal head growth and white matter injury in hypoplastic left heart syndrome.

Hinton RB, Andelfinger G, Sekar P, Hinton AC, Gendron RL, Michelfelder EC, Robitaille Y, Benson DW.

Pediatr Res. 2008 Oct;64(4):364-9. doi: 10.1203/PDR.0b013e3181827bf4.


Neurodevelopmental outcomes after staged palliation for hypoplastic left heart syndrome.

Tabbutt S, Nord AS, Jarvik GP, Bernbaum J, Wernovsky G, Gerdes M, Zackai E, Clancy RR, Nicolson SC, Spray TL, Gaynor JW.

Pediatrics. 2008 Mar;121(3):476-83. doi: 10.1542/peds.2007-1282.


ACOG Committee Opinion No. 394, December 2007. Cesarean delivery on maternal request.

American College of Obstetricians and Gynecologists..

Obstet Gynecol. 2007 Dec;110(6):1501.


Abnormal brain development in newborns with congenital heart disease.

Miller SP, McQuillen PS, Hamrick S, Xu D, Glidden DV, Charlton N, Karl T, Azakie A, Ferriero DM, Barkovich AJ, Vigneron DB.

N Engl J Med. 2007 Nov 8;357(19):1928-38.


A randomized clinical trial of regional cerebral perfusion versus deep hypothermic circulatory arrest: outcomes for infants with functional single ventricle.

Goldberg CS, Bove EL, Devaney EJ, Mollen E, Schwartz E, Tindall S, Nowak C, Charpie J, Brown MB, Kulik TJ, Ohye RG.

J Thorac Cardiovasc Surg. 2007 Apr;133(4):880-7. Epub 2007 Feb 22.


Aortic morphometry and microcephaly in hypoplastic left heart syndrome.

Shillingford AJ, Ittenbach RF, Marino BS, Rychik J, Clancy RR, Spray TL, Gaynor JW, Wernovsky G.

Cardiol Young. 2007 Apr;17(2):189-95. Epub 2007 Mar 5.


Congenital heart disease in the general population: changing prevalence and age distribution.

Marelli AJ, Mackie AS, Ionescu-Ittu R, Rahme E, Pilote L.

Circulation. 2007 Jan 16;115(2):163-72. Epub 2007 Jan 8.


Comparison of the WHO child growth standards and the CDC 2000 growth charts.

de Onis M, Garza C, Onyango AW, Borghi E.

J Nutr. 2007 Jan;137(1):144-8.


Relationship of patient and medical characteristics to health status in children and adolescents after the Fontan procedure.

McCrindle BW, Williams RV, Mitchell PD, Hsu DT, Paridon SM, Atz AM, Li JS, Newburger JW; Pediatric Heart Network Investigators..

Circulation. 2006 Feb 28;113(8):1123-9. Epub 2006 Feb 20.

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