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Items: 1 to 20 of 68


The origin of GPCRs: identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi.

Krishnan A, Almén MS, Fredriksson R, Schiöth HB.

PLoS One. 2012;7(1):e29817. doi: 10.1371/journal.pone.0029817. Epub 2012 Jan 4.


G protein-coupled receptor kinases: more than just kinases and not only for GPCRs.

Gurevich EV, Tesmer JJ, Mushegian A, Gurevich VV.

Pharmacol Ther. 2012 Jan;133(1):40-69. doi: 10.1016/j.pharmthera.2011.08.001. Epub 2011 Aug 26. Review.


Independent HHsearch, Needleman--Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families.

Nordström KJ, Sällman Almén M, Edstam MM, Fredriksson R, Schiöth HB.

Mol Biol Evol. 2011 Sep;28(9):2471-80. doi: 10.1093/molbev/msr061. Epub 2011 Mar 14.


Activation of G protein-coupled receptor kinase 1 involves interactions between its N-terminal region and its kinase domain.

Huang CC, Orban T, Jastrzebska B, Palczewski K, Tesmer JJ.

Biochemistry. 2011 Mar 22;50(11):1940-9. doi: 10.1021/bi101606e. Epub 2011 Feb 22.


Molecular basis for activation of G protein-coupled receptor kinases.

Boguth CA, Singh P, Huang CC, Tesmer JJ.

EMBO J. 2010 Oct 6;29(19):3249-59. doi: 10.1038/emboj.2010.206. Epub 2010 Aug 20.


G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.

Chen M, Philipp M, Wang J, Premont RT, Garrison TR, Caron MG, Lefkowitz RJ, Chen W.

J Biol Chem. 2009 Dec 11;284(50):35040-8. doi: 10.1074/jbc.M109.047456. Epub 2009 Oct 2.


Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation.

Pao CS, Barker BL, Benovic JL.

Biochemistry. 2009 Aug 4;48(30):7325-33. doi: 10.1021/bi900408g.


A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases.

Huang CC, Yoshino-Koh K, Tesmer JJ.

J Biol Chem. 2009 Jun 19;284(25):17206-15. doi: 10.1074/jbc.M809544200. Epub 2009 Apr 13.


Plasma membrane and nuclear localization of G protein coupled receptor kinase 6A.

Jiang X, Benovic JL, Wedegaertner PB.

Mol Biol Cell. 2007 Aug;18(8):2960-9. Epub 2007 May 30.


Survey sequencing and comparative analysis of the elephant shark (Callorhinchus milii) genome.

Venkatesh B, Kirkness EF, Loh YH, Halpern AL, Lee AP, Johnson J, Dandona N, Viswanathan LD, Tay A, Venter JC, Strausberg RL, Brenner S.

PLoS Biol. 2007 Apr;5(4):e101.


Insights into the evolutionary origin and genome architecture of the unicellular opisthokonts Capsaspora owczarzaki and Sphaeroforma arctica.

Ruiz-Trillo I, Lane CE, Archibald JM, Roger AJ.

J Eukaryot Microbiol. 2006 Sep-Oct;53(5):379-84.


Gene loss and evolutionary rates following whole-genome duplication in teleost fishes.

Brunet FG, Roest Crollius H, Paris M, Aury JM, Gibert P, Jaillon O, Laudet V, Robinson-Rechavi M.

Mol Biol Evol. 2006 Sep;23(9):1808-16. Epub 2006 Jun 29.


Genome duplication, extinction and vertebrate evolution.

Donoghue PC, Purnell MA.

Trends Ecol Evol. 2005 Jun;20(6):312-9.


The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs.

Lodowski DT, Tesmer VM, Benovic JL, Tesmer JJ.

J Biol Chem. 2006 Jun 16;281(24):16785-93. Epub 2006 Apr 13.


The structural basis of arrestin-mediated regulation of G-protein-coupled receptors.

Gurevich VV, Gurevich EV.

Pharmacol Ther. 2006 Jun;110(3):465-502. Epub 2006 Feb 3. Review.


Snapshot of activated G proteins at the membrane: the Galphaq-GRK2-Gbetagamma complex.

Tesmer VM, Kawano T, Shankaranarayanan A, Kozasa T, Tesmer JJ.

Science. 2005 Dec 9;310(5754):1686-90.


New roles for Galpha and RGS proteins: communication continues despite pulling sisters apart.

Wilkie TM, Kinch L.

Curr Biol. 2005 Oct 25;15(20):R843-54. Review.


The zebrafish gene map defines ancestral vertebrate chromosomes.

Woods IG, Wilson C, Friedlander B, Chang P, Reyes DK, Nix R, Kelly PD, Chu F, Postlethwait JH, Talbot WS.

Genome Res. 2005 Sep;15(9):1307-14. Epub 2005 Aug 18.


PHYML Online--a web server for fast maximum likelihood-based phylogenetic inference.

Guindon S, Lethiec F, Duroux P, Gascuel O.

Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W557-9.

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