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Items: 1 to 20 of 65

1.

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA.

Kowalinski E, Lunardi T, McCarthy AA, Louber J, Brunel J, Grigorov B, Gerlier D, Cusack S.

Cell. 2011 Oct 14;147(2):423-35. doi: 10.1016/j.cell.2011.09.039.

2.

Structural insights into RNA recognition by RIG-I.

Luo D, Ding SC, Vela A, Kohlway A, Lindenbach BD, Pyle AM.

Cell. 2011 Oct 14;147(2):409-22. doi: 10.1016/j.cell.2011.09.023.

3.

Structural basis of RNA recognition and activation by innate immune receptor RIG-I.

Jiang F, Ramanathan A, Miller MT, Tang GQ, Gale M Jr, Patel SS, Marcotrigiano J.

Nature. 2011 Sep 25;479(7373):423-7. doi: 10.1038/nature10537.

4.

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells.

Zhang Z, Yuan B, Bao M, Lu N, Kim T, Liu YJ.

Nat Immunol. 2011 Sep 4;12(10):959-65. doi: 10.1038/ni.2091. Erratum in: Nat Immunol. 2012 Feb;13(2):196.

5.

MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response.

Hou F, Sun L, Zheng H, Skaug B, Jiang QX, Chen ZJ.

Cell. 2011 Aug 5;146(3):448-61. doi: 10.1016/j.cell.2011.06.041. Epub 2011 Jul 21. Erratum in: Cell. 2011 Sep 2;146(5):841.

6.

DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells.

Zhang Z, Kim T, Bao M, Facchinetti V, Jung SY, Ghaffari AA, Qin J, Cheng G, Liu YJ.

Immunity. 2011 Jun 24;34(6):866-78. doi: 10.1016/j.immuni.2011.03.027.

7.

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection.

Kerur N, Veettil MV, Sharma-Walia N, Bottero V, Sadagopan S, Otageri P, Chandran B.

Cell Host Microbe. 2011 May 19;9(5):363-75. doi: 10.1016/j.chom.2011.04.008.

8.

Innate immune sensing of DNA viruses.

Rathinam VA, Fitzgerald KA.

Virology. 2011 Mar 15;411(2):153-62. doi: 10.1016/j.virol.2011.02.003. Epub 2011 Feb 18. Review.

9.

Nucleic acid recognition by the innate immune system.

Barbalat R, Ewald SE, Mouchess ML, Barton GM.

Annu Rev Immunol. 2011;29:185-214. doi: 10.1146/annurev-immunol-031210-101340. Review.

PMID:
21219183
10.

RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium.

Broquet AH, Hirata Y, McAllister CS, Kagnoff MF.

J Immunol. 2011 Feb 1;186(3):1618-26. doi: 10.4049/jimmunol.1002862. Epub 2010 Dec 27.

11.

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium.

Slater L, Bartlett NW, Haas JJ, Zhu J, Message SD, Walton RP, Sykes A, Dahdaleh S, Clarke DL, Belvisi MG, Kon OM, Fujita T, Jeffery PK, Johnston SL, Edwards MR.

PLoS Pathog. 2010 Nov 4;6(11):e1001178. doi: 10.1371/journal.ppat.1001178. Erratum in: PLoS Pathog. 2012 Apr;8(4): doi/10.1371/annotation/c3f58c59-a42f-495b-a4f2-d74d55d72166.

12.

IFI16 is an innate immune sensor for intracellular DNA.

Unterholzner L, Keating SE, Baran M, Horan KA, Jensen SB, Sharma S, Sirois CM, Jin T, Latz E, Xiao TS, Fitzgerald KA, Paludan SR, Bowie AG.

Nat Immunol. 2010 Nov;11(11):997-1004. doi: 10.1038/ni.1932. Epub 2010 Oct 3.

13.

Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells.

Kim T, Pazhoor S, Bao M, Zhang Z, Hanabuchi S, Facchinetti V, Bover L, Plumas J, Chaperot L, Qin J, Liu YJ.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15181-6. doi: 10.1073/pnas.1006539107. Epub 2010 Aug 9.

14.

Inflammasomes and anti-viral immunity.

Rathinam VA, Fitzgerald KA.

J Clin Immunol. 2010 Sep;30(5):632-7. doi: 10.1007/s10875-010-9431-4. Epub 2010 Jul 28. Review.

PMID:
20665097
15.

The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway.

Yang P, An H, Liu X, Wen M, Zheng Y, Rui Y, Cao X.

Nat Immunol. 2010 Jun;11(6):487-94. doi: 10.1038/ni.1876. Epub 2010 May 9.

PMID:
20453844
16.

Peroxisomes are signaling platforms for antiviral innate immunity.

Dixit E, Boulant S, Zhang Y, Lee AS, Odendall C, Shum B, Hacohen N, Chen ZJ, Whelan SP, Fransen M, Nibert ML, Superti-Furga G, Kagan JC.

Cell. 2010 May 14;141(4):668-81. doi: 10.1016/j.cell.2010.04.018. Epub 2010 May 6.

17.

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity.

Zeng W, Sun L, Jiang X, Chen X, Hou F, Adhikari A, Xu M, Chen ZJ.

Cell. 2010 Apr 16;141(2):315-30. doi: 10.1016/j.cell.2010.03.029.

18.

Influenza virus activates inflammasomes via its intracellular M2 ion channel.

Ichinohe T, Pang IK, Iwasaki A.

Nat Immunol. 2010 May;11(5):404-10. doi: 10.1038/ni.1861. Epub 2010 Apr 11.

19.

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis.

Fernandes-Alnemri T, Yu JW, Juliana C, Solorzano L, Kang S, Wu J, Datta P, McCormick M, Huang L, McDermott E, Eisenlohr L, Landel CP, Alnemri ES.

Nat Immunol. 2010 May;11(5):385-93. doi: 10.1038/ni.1859. Epub 2010 Mar 28.

20.

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.

Rathinam VA, Jiang Z, Waggoner SN, Sharma S, Cole LE, Waggoner L, Vanaja SK, Monks BG, Ganesan S, Latz E, Hornung V, Vogel SN, Szomolanyi-Tsuda E, Fitzgerald KA.

Nat Immunol. 2010 May;11(5):395-402. doi: 10.1038/ni.1864. Epub 2010 Mar 28.

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