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Items: 1 to 20 of 27

1.

Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death.

Volpicelli-Daley LA, Luk KC, Patel TP, Tanik SA, Riddle DM, Stieber A, Meaney DF, Trojanowski JQ, Lee VM.

Neuron. 2011 Oct 6;72(1):57-71. doi: 10.1016/j.neuron.2011.08.033.

2.

Assessment of α-synuclein secretion in mouse and human brain parenchyma.

Emmanouilidou E, Elenis D, Papasilekas T, Stranjalis G, Gerozissis K, Ioannou PC, Vekrellis K.

PLoS One. 2011;6(7):e22225. doi: 10.1371/journal.pone.0022225. Epub 2011 Jul 14.

3.

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study.

Mollenhauer B, Locascio JJ, Schulz-Schaeffer W, Sixel-Döring F, Trenkwalder C, Schlossmacher MG.

Lancet Neurol. 2011 Mar;10(3):230-40. doi: 10.1016/S1474-4422(11)70014-X. Erratum in: Lancet Neurol. 2011 Apr;10(4):297.

PMID:
21317042
4.

Quantification of α-synuclein in cerebrospinal fluid as a biomarker candidate: review of the literature and considerations for future studies.

Mollenhauer B, El-Agnaf OM, Marcus K, Trenkwalder C, Schlossmacher MG.

Biomark Med. 2010 Oct;4(5):683-99. doi: 10.2217/bmm.10.90. Review.

PMID:
20945981
5.

DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease.

Hong Z, Shi M, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Zabetian CP, Leverenz JB, Baird G, Montine TJ, Hancock AM, Hwang H, Pan C, Bradner J, Kang UJ, Jensen PH, Zhang J.

Brain. 2010 Mar;133(Pt 3):713-26. doi: 10.1093/brain/awq008. Epub 2010 Feb 15.

6.

Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes.

Kuo YM, Li Z, Jiao Y, Gaborit N, Pani AK, Orrison BM, Bruneau BG, Giasson BI, Smeyne RJ, Gershon MD, Nussbaum RL.

Hum Mol Genet. 2010 May 1;19(9):1633-50. doi: 10.1093/hmg/ddq038. Epub 2010 Jan 27.

7.

Choroid plexus: biology and pathology.

Wolburg H, Paulus W.

Acta Neuropathol. 2010 Jan;119(1):75-88. doi: 10.1007/s00401-009-0627-8. Epub 2009 Dec 24. Review.

PMID:
20033190
8.

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein.

Desplats P, Lee HJ, Bae EJ, Patrick C, Rockenstein E, Crews L, Spencer B, Masliah E, Lee SJ.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13010-5. doi: 10.1073/pnas.0903691106. Epub 2009 Jul 27. Erratum in: Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17606.

9.

Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.

Cullen V, Lindfors M, Ng J, Paetau A, Swinton E, Kolodziej P, Boston H, Saftig P, Woulfe J, Feany MB, Myllykangas L, Schlossmacher MG, Tyynelä J.

Mol Brain. 2009 Feb 9;2:5. doi: 10.1186/1756-6606-2-5.

10.

GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein.

Scherzer CR, Grass JA, Liao Z, Pepivani I, Zheng B, Eklund AC, Ney PA, Ng J, McGoldrick M, Mollenhauer B, Bresnick EH, Schlossmacher MG.

Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10907-12. doi: 10.1073/pnas.0802437105. Epub 2008 Jul 31.

11.

Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration.

Mollenhauer B, Cullen V, Kahn I, Krastins B, Outeiro TF, Pepivani I, Ng J, Schulz-Schaeffer W, Kretzschmar HA, McLean PJ, Trenkwalder C, Sarracino DA, Vonsattel JP, Locascio JJ, El-Agnaf OM, Schlossmacher MG.

Exp Neurol. 2008 Oct;213(2):315-25. doi: 10.1016/j.expneurol.2008.06.004. Epub 2008 Jun 14.

PMID:
18625222
12.
13.

Lumbosacral cerebrospinal fluid volume in humans using three-dimensional magnetic resonance imaging.

Sullivan JT, Grouper S, Walker MT, Parrish TB, McCarthy RJ, Wong CA.

Anesth Analg. 2006 Nov;103(5):1306-10.

PMID:
17056974
14.

The choroid plexus removes beta-amyloid from brain cerebrospinal fluid.

Crossgrove JS, Li GJ, Zheng W.

Exp Biol Med (Maywood). 2005 Nov;230(10):771-6.

15.

Diagnosing idiopathic normal-pressure hydrocephalus.

Relkin N, Marmarou A, Klinge P, Bergsneider M, Black PM.

Neurosurgery. 2005 Sep;57(3 Suppl):S4-16; discussion ii-v. Review.

PMID:
16160425
16.

Intravesicular localization and exocytosis of alpha-synuclein and its aggregates.

Lee HJ, Patel S, Lee SJ.

J Neurosci. 2005 Jun 22;25(25):6016-24.

17.

Essential tremor associated with focal nonnigral Lewy bodies: a clinicopathologic study.

Louis ED, Honig LS, Vonsattel JP, Maraganore DM, Borden S, Moskowitz CB.

Arch Neurol. 2005 Jun;62(6):1004-7.

PMID:
15956174
18.

alpha-Synuclein locus triplication causes Parkinson's disease.

Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, Kachergus J, Hulihan M, Peuralinna T, Dutra A, Nussbaum R, Lincoln S, Crawley A, Hanson M, Maraganore D, Adler C, Cookson MR, Muenter M, Baptista M, Miller D, Blancato J, Hardy J, Gwinn-Hardy K.

Science. 2003 Oct 31;302(5646):841. No abstract available.

19.

Proteins in cerebrospinal fluid and blood: barriers, CSF flow rate and source-related dynamics.

Reiber H.

Restor Neurol Neurosci. 2003;21(3-4):79-96. Review.

PMID:
14530572
20.

Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies.

Schlossmacher MG, Frosch MP, Gai WP, Medina M, Sharma N, Forno L, Ochiishi T, Shimura H, Sharon R, Hattori N, Langston JW, Mizuno Y, Hyman BT, Selkoe DJ, Kosik KS.

Am J Pathol. 2002 May;160(5):1655-67.

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