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Items: 1 to 20 of 48

1.

Regulation of alternative splicing by the core spliceosomal machinery.

Saltzman AL, Pan Q, Blencowe BJ.

Genes Dev. 2011 Feb 15;25(4):373-84. doi: 10.1101/gad.2004811.

2.

The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5' splice site cleavage during pre-mRNA splicing.

Koodathingal P, Novak T, Piccirilli JA, Staley JP.

Mol Cell. 2010 Aug 13;39(3):385-95. doi: 10.1016/j.molcel.2010.07.014.

3.

Exon sequences at the splice junctions affect splicing fidelity and alternative splicing.

Crotti LB, Horowitz DS.

Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):18954-9. doi: 10.1073/pnas.0907948106. Epub 2009 Oct 23.

4.

Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps.

Mefford MA, Staley JP.

RNA. 2009 Jul;15(7):1386-97. doi: 10.1261/rna.1582609. Epub 2009 May 20.

5.

The spliceosome: design principles of a dynamic RNP machine.

Wahl MC, Will CL, Lührmann R.

Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009. Review.

6.

Structure and function of an RNase H domain at the heart of the spliceosome.

Pena V, Rozov A, Fabrizio P, Lührmann R, Wahl MC.

EMBO J. 2008 Nov 5;27(21):2929-40. doi: 10.1038/emboj.2008.209. Epub 2008 Oct 9.

7.

Structural elucidation of a PRP8 core domain from the heart of the spliceosome.

Ritchie DB, Schellenberg MJ, Gesner EM, Raithatha SA, Stuart DT, Macmillan AM.

Nat Struct Mol Biol. 2008 Nov;15(11):1199-205. doi: 10.1038/nsmb.1505. Epub 2008 Oct 2.

PMID:
18836455
8.

Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins.

Yang K, Zhang L, Xu T, Heroux A, Zhao R.

Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13817-22. doi: 10.1073/pnas.0805960105. Epub 2008 Sep 8.

9.

"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.

Smith DJ, Query CC, Konarska MM.

Mol Cell. 2008 Jun 20;30(6):657-66. doi: 10.1016/j.molcel.2008.04.013. Review.

10.

Isolation of an active step I spliceosome and composition of its RNP core.

Bessonov S, Anokhina M, Will CL, Urlaub H, Lührmann R.

Nature. 2008 Apr 17;452(7189):846-50. doi: 10.1038/nature06842. Epub 2008 Mar 5.

PMID:
18322460
11.

RS domain-splicing signal interactions in splicing of U12-type and U2-type introns.

Shen H, Green MR.

Nat Struct Mol Biol. 2007 Jul;14(7):597-603. Epub 2007 Jul 1.

PMID:
17603499
12.

Opposing classes of prp8 alleles modulate the transition between the catalytic steps of pre-mRNA splicing.

Liu L, Query CC, Konarska MM.

Nat Struct Mol Biol. 2007 Jun;14(6):519-26. Epub 2007 May 7.

PMID:
17486100
13.
14.
15.

Intron removal requires proofreading of U2AF/3' splice site recognition by DEK.

Soares LM, Zanier K, Mackereth C, Sattler M, Valcárcel J.

Science. 2006 Jun 30;312(5782):1961-5.

16.

Exon ligation is proofread by the DExD/H-box ATPase Prp22p.

Mayas RM, Maita H, Staley JP.

Nat Struct Mol Biol. 2006 Jun;13(6):482-90. Epub 2006 May 7.

17.

Repositioning of the reaction intermediate within the catalytic center of the spliceosome.

Konarska MM, Vilardell J, Query CC.

Mol Cell. 2006 Feb 17;21(4):543-53.

18.

Insights into the mechanisms of splicing: more lessons from the ribosome.

Konarska MM, Query CC.

Genes Dev. 2005 Oct 1;19(19):2255-60. Review. No abstract available.

20.

Prp8 protein: at the heart of the spliceosome.

Grainger RJ, Beggs JD.

RNA. 2005 May;11(5):533-57. Review.

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