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Items: 1 to 20 of 57


Medroxyprogesterone acetate antagonizes estrogen up-regulation of brain mitochondrial function.

Irwin RW, Yao J, Ahmed SS, Hamilton RT, Cadenas E, Brinton RD.

Endocrinology. 2011 Feb;152(2):556-67. doi: 10.1210/en.2010-1061. Epub 2010 Dec 15.


Estrogen protection against mitochondrial toxin-induced cell death in hippocampal neurons: antagonism by progesterone.

Yao J, Chen S, Cadenas E, Brinton RD.

Brain Res. 2011 Mar 16;1379:2-10. doi: 10.1016/j.brainres.2010.11.090. Epub 2010 Dec 4.


Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence.

Yao J, Hamilton RT, Cadenas E, Brinton RD.

Biochim Biophys Acta. 2010 Oct;1800(10):1121-6. doi: 10.1016/j.bbagen.2010.06.002. Epub 2010 Jun 9.


Interactions of estradiol and insulin-like growth factor-I signalling in the nervous system: new advances.

Garcia-Segura LM, Arévalo MA, Azcoitia I.

Prog Brain Res. 2010;181:251-72. doi: 10.1016/S0079-6123(08)81014-X. Review.


Aging-related gene expression in hippocampus proper compared with dentate gyrus is selectively associated with metabolic syndrome variables in rhesus monkeys.

Blalock EM, Grondin R, Chen KC, Thibault O, Thibault V, Pandya JD, Dowling A, Zhang Z, Sullivan P, Porter NM, Landfield PW.

J Neurosci. 2010 Apr 28;30(17):6058-71. doi: 10.1523/JNEUROSCI.3956-09.2010.


Continuous and cyclic progesterone differentially interact with estradiol in the regulation of Alzheimer-like pathology in female 3xTransgenic-Alzheimer's disease mice.

Carroll JC, Rosario ER, Villamagna A, Pike CJ.

Endocrinology. 2010 Jun;151(6):2713-22. doi: 10.1210/en.2009-1487. Epub 2010 Apr 21.


Toward a comprehensive neurobiology of IGF-I.

Torres-Aleman I.

Dev Neurobiol. 2010 Apr;70(5):384-96. doi: 10.1002/dneu.20778. Review.


Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling.

Cox AG, Winterbourn CC, Hampton MB.

Biochem J. 2009 Dec 23;425(2):313-25. doi: 10.1042/BJ20091541. Review.


Progesterone and dexamethasone differentially regulate the IGF-system in glial cells.

Chesik D, De Keyser J.

Neurosci Lett. 2010 Jan 14;468(3):178-82. doi: 10.1016/j.neulet.2009.10.051. Epub 2009 Oct 22.


Liver X receptor in cholesterol metabolism.

Zhao C, Dahlman-Wright K.

J Endocrinol. 2010 Mar;204(3):233-40. doi: 10.1677/JOE-09-0271. Epub 2009 Oct 16. Review.


Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease.

Yao J, Irwin RW, Zhao L, Nilsen J, Hamilton RT, Brinton RD.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14670-5. doi: 10.1073/pnas.0903563106. Epub 2009 Aug 10.


Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}.

Zhao WQ, Lacor PN, Chen H, Lambert MP, Quon MJ, Krafft GA, Klein WL.

J Biol Chem. 2009 Jul 10;284(28):18742-53. doi: 10.1074/jbc.M109.011015. Epub 2009 Apr 30.


Progesterone increases rat neural progenitor cell cycle gene expression and proliferation via extracellularly regulated kinase and progesterone receptor membrane components 1 and 2.

Liu L, Wang J, Zhao L, Nilsen J, McClure K, Wong K, Brinton RD.

Endocrinology. 2009 Jul;150(7):3186-96. doi: 10.1210/en.2008-1447. Epub 2009 Apr 9.


Mitochondrial ATP-synthase in the entorhinal cortex is a target of oxidative stress at stages I/II of Alzheimer's disease pathology.

Terni B, Boada J, Portero-Otin M, Pamplona R, Ferrer I.

Brain Pathol. 2010 Jan;20(1):222-33. doi: 10.1111/j.1750-3639.2009.00266.x. Epub 2009 Feb 27.


Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment.

Kadish I, Thibault O, Blalock EM, Chen KC, Gant JC, Porter NM, Landfield PW.

J Neurosci. 2009 Feb 11;29(6):1805-16. doi: 10.1523/JNEUROSCI.4599-08.2009.


PGRMC1 (progesterone receptor membrane component 1): a targetable protein with multiple functions in steroid signaling, P450 activation and drug binding.

Rohe HJ, Ahmed IS, Twist KE, Craven RJ.

Pharmacol Ther. 2009 Jan;121(1):14-9. doi: 10.1016/j.pharmthera.2008.09.006. Epub 2008 Nov 1. Review.


Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signaling.

Sharma S, Prasanthi R P J, Schommer E, Feist G, Ghribi O.

Neurobiol Dis. 2008 Dec;32(3):426-32. doi: 10.1016/j.nbd.2008.08.002. Epub 2008 Aug 16.


The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology.

Cole SL, Vassar R.

J Biol Chem. 2008 Oct 31;283(44):29621-5. doi: 10.1074/jbc.R800015200. Epub 2008 Jul 23. Review.

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