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Items: 1 to 20 of 47

1.

A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans.

Walker AK, Jacobs RL, Watts JL, Rottiers V, Jiang K, Finnegan DM, Shioda T, Hansen M, Yang F, Niebergall LJ, Vance DE, Tzoneva M, Hart AC, Näär AM.

Cell. 2011 Nov 11;147(4):840-52. doi: 10.1016/j.cell.2011.09.045. Epub 2011 Oct 27.

2.

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity.

Fu S, Yang L, Li P, Hofmann O, Dicker L, Hide W, Lin X, Watkins SM, Ivanov AR, Hotamisligil GS.

Nature. 2011 May 26;473(7348):528-31. doi: 10.1038/nature09968. Epub 2011 May 1.

3.

Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.

Calvisi DF, Wang C, Ho C, Ladu S, Lee SA, Mattu S, Destefanis G, Delogu S, Zimmermann A, Ericsson J, Brozzetti S, Staniscia T, Chen X, Dombrowski F, Evert M.

Gastroenterology. 2011 Mar;140(3):1071-83. doi: 10.1053/j.gastro.2010.12.006. Epub 2010 Dec 11.

4.

Endoplasmic reticulum stress in liver disease.

Malhi H, Kaufman RJ.

J Hepatol. 2011 Apr;54(4):795-809. doi: 10.1016/j.jhep.2010.11.005. Epub 2010 Nov 13. Review.

5.

Redox signaling and the innate immune system in alcoholic liver disease.

Cohen JI, Chen X, Nagy LE.

Antioxid Redox Signal. 2011 Jul 15;15(2):523-34. doi: 10.1089/ars.2010.3746. Epub 2011 May 25. Review.

6.
7.

Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism.

Christensen KE, Wu Q, Wang X, Deng L, Caudill MA, Rozen R.

J Nutr. 2010 Oct;140(10):1736-41. doi: 10.3945/jn.110.124917. Epub 2010 Aug 19.

PMID:
20724492
8.
9.

Variant in PNPLA3 is associated with alcoholic liver disease.

Tian C, Stokowski RP, Kershenobich D, Ballinger DG, Hinds DA.

Nat Genet. 2010 Jan;42(1):21-3. doi: 10.1038/ng.488. Epub 2009 Nov 29.

PMID:
19946271
10.

Immune mechanisms in alcoholic liver disease.

Albano E, Vidali M.

Genes Nutr. 2010 Jun;5(2):141-7. doi: 10.1007/s12263-009-0151-4. Epub 2009 Oct 7.

11.

Current experimental perspectives on the clinical progression of alcoholic liver disease.

Breitkopf K, Nagy LE, Beier JI, Mueller S, Weng H, Dooley S.

Alcohol Clin Exp Res. 2009 Oct;33(10):1647-55. doi: 10.1111/j.1530-0277.2009.01015.x. Epub 2009 Jul 23. Review.

PMID:
19645734
12.

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans.

Harrill AH, Watkins PB, Su S, Ross PK, Harbourt DE, Stylianou IM, Boorman GA, Russo MW, Sackler RS, Harris SC, Smith PC, Tennant R, Bogue M, Paigen K, Harris C, Contractor T, Wiltshire T, Rusyn I, Threadgill DW.

Genome Res. 2009 Sep;19(9):1507-15. doi: 10.1101/gr.090241.108. Epub 2009 May 5.

13.

Homocysteine and lipids: S-adenosyl methionine as a key intermediate.

Obeid R, Herrmann W.

FEBS Lett. 2009 Apr 17;583(8):1215-25. doi: 10.1016/j.febslet.2009.03.038. Epub 2009 Mar 25. Review. Erratum in: FEBS Lett. 2009 Sep 17;583(18):3107.

14.

Alcohol and genetic polymorphisms: effect on risk of alcohol-related cancer.

Druesne-Pecollo N, Tehard B, Mallet Y, Gerber M, Norat T, Hercberg S, Latino-Martel P.

Lancet Oncol. 2009 Feb;10(2):173-80. doi: 10.1016/S1470-2045(09)70019-1. Review.

PMID:
19185835
15.

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

Rutkowski DT, Wu J, Back SH, Callaghan MU, Ferris SP, Iqbal J, Clark R, Miao H, Hassler JR, Fornek J, Katze MG, Hussain MM, Song B, Swathirajan J, Wang J, Yau GD, Kaufman RJ.

Dev Cell. 2008 Dec;15(6):829-40. doi: 10.1016/j.devcel.2008.10.015.

16.

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.

Romeo S, Kozlitina J, Xing C, Pertsemlidis A, Cox D, Pennacchio LA, Boerwinkle E, Cohen JC, Hobbs HH.

Nat Genet. 2008 Dec;40(12):1461-5. doi: 10.1038/ng.257. Epub 2008 Sep 25.

17.

Quantifying the risk for alcohol-use and alcohol-attributable health disorders: present findings and future research needs.

Li TK.

J Gastroenterol Hepatol. 2008 Mar;23 Suppl 1:S2-8. doi: 10.1111/j.1440-1746.2007.05298.x. Review.

PMID:
18336658
18.

Dissection of endoplasmic reticulum stress signaling in alcoholic and non-alcoholic liver injury.

Ji C.

J Gastroenterol Hepatol. 2008 Mar;23 Suppl 1:S16-24. doi: 10.1111/j.1440-1746.2007.05276.x. Review.

19.

Methionine metabolism and liver disease.

Mato JM, Martínez-Chantar ML, Lu SC.

Annu Rev Nutr. 2008;28:273-93. doi: 10.1146/annurev.nutr.28.061807.155438. Review.

PMID:
18331185
20.

The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics.

Roberts A, Pardo-Manuel de Villena F, Wang W, McMillan L, Threadgill DW.

Mamm Genome. 2007 Jul;18(6-7):473-81. Epub 2007 Aug 3.

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