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Items: 1 to 20 of 38


Integrin α5β1 facilitates cancer cell invasion through enhanced contractile forces.

Mierke CT, Frey B, Fellner M, Herrmann M, Fabry B.

J Cell Sci. 2011 Feb 1;124(Pt 3):369-83. doi: 10.1242/jcs.071985. Epub 2011 Jan 11.


Ligand-independent activation of c-Met by fibronectin and α(5)β(1)-integrin regulates ovarian cancer invasion and metastasis.

Mitra AK, Sawada K, Tiwari P, Mui K, Gwin K, Lengyel E.

Oncogene. 2011 Mar 31;30(13):1566-76. doi: 10.1038/onc.2010.532. Epub 2010 Nov 29.


Ovarian cancer development and metastasis.

Lengyel E.

Am J Pathol. 2010 Sep;177(3):1053-64. doi: 10.2353/ajpath.2010.100105. Epub 2010 Jul 22.


The biomechanical integrin.

Baker EL, Zaman MH.

J Biomech. 2010 Jan 5;43(1):38-44. doi: 10.1016/j.jbiomech.2009.09.007. Epub 2009 Oct 6. Review.


Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction.

Roca-Cusachs P, Gauthier NC, Del Rio A, Sheetz MP.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16245-50. doi: 10.1073/pnas.0902818106. Epub 2009 Sep 3.


Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment.

Schafer ZT, Grassian AR, Song L, Jiang Z, Gerhart-Hines Z, Irie HY, Gao S, Puigserver P, Brugge JS.

Nature. 2009 Sep 3;461(7260):109-13. doi: 10.1038/nature08268. Epub 2009 Aug 19.


Talin depletion reveals independence of initial cell spreading from integrin activation and traction.

Zhang X, Jiang G, Cai Y, Monkley SJ, Critchley DR, Sheetz MP.

Nat Cell Biol. 2008 Sep;10(9):1062-8. doi: 10.1038/ncb1765.


Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed.

Gardel ML, Sabass B, Ji L, Danuser G, Schwarz US, Waterman CM.

J Cell Biol. 2008 Dec 15;183(6):999-1005. doi: 10.1083/jcb.200810060.


A binding domain on mesothelin for CA125/MUC16.

Kaneko O, Gong L, Zhang J, Hansen JK, Hassan R, Lee B, Ho M.

J Biol Chem. 2009 Feb 6;284(6):3739-49. doi: 10.1074/jbc.M806776200. Epub 2008 Dec 15.


Binding of soluble fibronectin to integrin alpha5 beta1 - link to focal adhesion redistribution and contractile shape.

Huveneers S, Truong H, Fässler R, Sonnenberg A, Danen EH.

J Cell Sci. 2008 Aug 1;121(Pt 15):2452-62. doi: 10.1242/jcs.033001. Epub 2008 Jul 8.


Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target.

Sawada K, Mitra AK, Radjabi AR, Bhaskar V, Kistner EO, Tretiakova M, Jagadeeswaran S, Montag A, Becker A, Kenny HA, Peter ME, Ramakrishnan V, Yamada SD, Lengyel E.

Cancer Res. 2008 Apr 1;68(7):2329-39. doi: 10.1158/0008-5472.CAN-07-5167.


The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.

Kenny HA, Kaur S, Coussens LM, Lengyel E.

J Clin Invest. 2008 Apr;118(4):1367-79. doi: 10.1172/JCI33775.


High resolution traction force microscopy based on experimental and computational advances.

Sabass B, Gardel ML, Waterman CM, Schwarz US.

Biophys J. 2008 Jan 1;94(1):207-20. Epub 2007 Sep 7.


Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes.

Ince TA, Richardson AL, Bell GW, Saitoh M, Godar S, Karnoub AE, Iglehart JD, Weinberg RA.

Cancer Cell. 2007 Aug;12(2):160-70.


Cellular remodelling of individual collagen fibrils visualized by time-lapse AFM.

Friedrichs J, Taubenberger A, Franz CM, Muller DJ.

J Mol Biol. 2007 Sep 21;372(3):594-607. Epub 2007 Jul 3.


Disaggregation and invasion of ovarian carcinoma ascites spheroids.

Burleson KM, Boente MP, Pambuccian SE, Skubitz AP.

J Transl Med. 2006 Jan 24;4:6.


Tumour-induced apoptosis in human mesothelial cells: a mechanism of peritoneal invasion by Fas Ligand/Fas interaction.

Heath RM, Jayne DG, O'Leary R, Morrison EE, Guillou PJ.

Br J Cancer. 2004 Apr 5;90(7):1437-42.


Ovarian carcinoma ascites spheroids adhere to extracellular matrix components and mesothelial cell monolayers.

Burleson KM, Casey RC, Skubitz KM, Pambuccian SE, Oegema TR Jr, Skubitz AP.

Gynecol Oncol. 2004 Apr;93(1):170-81.


Fibronectin matrix assembly regulates alpha5beta1-mediated cell cohesion.

Robinson EE, Foty RA, Corbett SA.

Mol Biol Cell. 2004 Mar;15(3):973-81. Epub 2004 Jan 12.

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