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Items: 1 to 20 of 45

1.

A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.

Ramos PS, Criswell LA, Moser KL, Comeau ME, Williams AH, Pajewski NM, Chung SA, Graham RR, Zidovetzki R, Kelly JA, Kaufman KM, Jacob CO, Vyse TJ, Tsao BP, Kimberly RP, Gaffney PM, Alarcón-Riquelme ME, Harley JB, Langefeld CD; International Consortium on the Genetics of Systemic Erythematosus..

PLoS Genet. 2011 Dec;7(12):e1002406. doi: 10.1371/journal.pgen.1002406.

2.

Pervasive sharing of genetic effects in autoimmune disease.

Cotsapas C, Voight BF, Rossin E, Lage K, Neale BM, Wallace C, Abecasis GR, Barrett JC, Behrens T, Cho J, De Jager PL, Elder JT, Graham RR, Gregersen P, Klareskog L, Siminovitch KA, van Heel DA, Wijmenga C, Worthington J, Todd JA, Hafler DA, Rich SS, Daly MJ; FOCiS Network of Consortia..

PLoS Genet. 2011 Aug;7(8):e1002254. doi: 10.1371/journal.pgen.1002254.

3.

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

International Multiple Sclerosis Genetics Consortium.; Wellcome Trust Case Control Consortium 2., Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, Moutsianas L, Dilthey A, Su Z, Freeman C, Hunt SE, Edkins S, Gray E, Booth DR, Potter SC, Goris A, Band G, Oturai AB, Strange A, Saarela J, Bellenguez C, Fontaine B, Gillman M, Hemmer B, Gwilliam R, Zipp F, Jayakumar A, Martin R, Leslie S, Hawkins S, Giannoulatou E, D'alfonso S, Blackburn H, Martinelli Boneschi F, Liddle J, Harbo HF, Perez ML, Spurkland A, Waller MJ, Mycko MP, Ricketts M, Comabella M, Hammond N, Kockum I, McCann OT, Ban M, Whittaker P, Kemppinen A, Weston P, Hawkins C, Widaa S, Zajicek J, Dronov S, Robertson N, Bumpstead SJ, Barcellos LF, Ravindrarajah R, Abraham R, Alfredsson L, Ardlie K, Aubin C, Baker A, Baker K, Baranzini SE, Bergamaschi L, Bergamaschi R, Bernstein A, Berthele A, Boggild M, Bradfield JP, Brassat D, Broadley SA, Buck D, Butzkueven H, Capra R, Carroll WM, Cavalla P, Celius EG, Cepok S, Chiavacci R, Clerget-Darpoux F, Clysters K, Comi G, Cossburn M, Cournu-Rebeix I, Cox MB, Cozen W, Cree BA, Cross AH, Cusi D, Daly MJ, Davis E, de Bakker PI, Debouverie M, D'hooghe MB, Dixon K, Dobosi R, Dubois B, Ellinghaus D, Elovaara I, Esposito F, Fontenille C, Foote S, Franke A, Galimberti D, Ghezzi A, Glessner J, Gomez R, Gout O, Graham C, Grant SF, Guerini FR, Hakonarson H, Hall P, Hamsten A, Hartung HP, Heard RN, Heath S, Hobart J, Hoshi M, Infante-Duarte C, Ingram G, Ingram W, Islam T, Jagodic M, Kabesch M, Kermode AG, Kilpatrick TJ, Kim C, Klopp N, Koivisto K, Larsson M, Lathrop M, Lechner-Scott JS, Leone MA, Leppä V, Liljedahl U, Bomfim IL, Lincoln RR, Link J, Liu J, Lorentzen AR, Lupoli S, Macciardi F, Mack T, Marriott M, Martinelli V, Mason D, McCauley JL, Mentch F, Mero IL, Mihalova T, Montalban X, Mottershead J, Myhr KM, Naldi P, Ollier W, Page A, Palotie A, Pelletier J, Piccio L, Pickersgill T, Piehl F, Pobywajlo S, Quach HL, Ramsay PP, Reunanen M, Reynolds R, Rioux JD, Rodegher M, Roesner S, Rubio JP, Rückert IM, Salvetti M, Salvi E, Santaniello A, Schaefer CA, Schreiber S, Schulze C, Scott RJ, Sellebjerg F, Selmaj KW, Sexton D, Shen L, Simms-Acuna B, Skidmore S, Sleiman PM, Smestad C, Sørensen PS, Søndergaard HB, Stankovich J, Strange RC, Sulonen AM, Sundqvist E, Syvänen AC, Taddeo F, Taylor B, Blackwell JM, Tienari P, Bramon E, Tourbah A, Brown MA, Tronczynska E, Casas JP, Tubridy N, Corvin A, Vickery J, Jankowski J, Villoslada P, Markus HS, Wang K, Mathew CG, Wason J, Palmer CN, Wichmann HE, Plomin R, Willoughby E, Rautanen A, Winkelmann J, Wittig M, Trembath RC, Yaouanq J, Viswanathan AC, Zhang H, Wood NW, Zuvich R, Deloukas P, Langford C, Duncanson A, Oksenberg JR, Pericak-Vance MA, Haines JL, Olsson T, Hillert J, Ivinson AJ, De Jager PL, Peltonen L, Stewart GJ, Hafler DA, Hauser SL, McVean G, Donnelly P, Compston A.

Nature. 2011 Aug 10;476(7359):214-9. doi: 10.1038/nature10251.

4.

New IBD genetics: common pathways with other diseases.

Lees CW, Barrett JC, Parkes M, Satsangi J.

Gut. 2011 Dec;60(12):1739-53. doi: 10.1136/gut.2009.199679. Review.

PMID:
21300624
5.

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease.

Festen EA, Goyette P, Green T, Boucher G, Beauchamp C, Trynka G, Dubois PC, Lagacé C, Stokkers PC, Hommes DW, Barisani D, Palmieri O, Annese V, van Heel DA, Weersma RK, Daly MJ, Wijmenga C, Rioux JD.

PLoS Genet. 2011 Jan 27;7(1):e1001283. doi: 10.1371/journal.pgen.1001283.

6.

Genetic predisposition to autoimmunity--what have we learned?

Rai E, Wakeland EK.

Semin Immunol. 2011 Apr;23(2):67-83. doi: 10.1016/j.smim.2011.01.015. Review.

PMID:
21288738
7.

Revealing the genetic basis of multiple sclerosis: are we there yet?

Baranzini SE.

Curr Opin Genet Dev. 2011 Jun;21(3):317-24. doi: 10.1016/j.gde.2010.12.006. Review.

8.

Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease.

Danoy P, Pryce K, Hadler J, Bradbury LA, Farrar C, Pointon J; Australo-Anglo-American Spondyloarthritis Consortium., Ward M, Weisman M, Reveille JD, Wordsworth BP, Stone MA; Spondyloarthritis Research Consortium of Canada., Maksymowych WP, Rahman P, Gladman D, Inman RD, Brown MA.

PLoS Genet. 2010 Dec 2;6(12):e1001195. doi: 10.1371/journal.pgen.1001195. Erratum in: PLoS Genet. 2011 Feb;7(2). doi: 10.1371/annotation/0ee7d13b-c55e-4be6-ab3e-8e8df5bb2c97. PLoS Genet. 2011 Feb;7(2). doi: 10.1371/annotation/9a856455-cdc3-436c-b6c4-7b881da4eebe.

9.

Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis.

Laukens D, Georges M, Libioulle C, Sandor C, Mni M, Vander Cruyssen B, Peeters H, Elewaut D, De Vos M.

PLoS One. 2010 Nov 2;5(11):e13795. doi: 10.1371/journal.pone.0013795.

10.

Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.

Orozco G, Eyre S, Hinks A, Bowes J, Morgan AW, Wilson AG, Wordsworth P, Steer S, Hocking L; UKRAG consortium., Thomson W, Worthington J, Barton A.

Ann Rheum Dis. 2011 Mar;70(3):463-8. doi: 10.1136/ard.2010.137174.

11.

Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease.

Eyre S, Hinks A, Bowes J, Flynn E, Martin P, Wilson AG, Morgan AW, Emery P, Steer S, Hocking LJ, Reid DM, Harrison P, Wordsworth P; Yorkshire Early Arthritis Consortium.; Biologics in RA Control Consortium., Thomson W, Worthington J, Barton A.

Arthritis Res Ther. 2010;12(5):R175. doi: 10.1186/ar3139.

12.

The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1.

Thompson SD, Sudman M, Ramos PS, Marion MC, Ryan M, Tsoras M, Weiler T, Wagner M, Keddache M, Haas JP, Mueller C, Prahalad S, Bohnsack J, Wise CA, Punaro M, Zhang D, Rosé CD, Comeau ME, Divers J, Glass DN, Langefeld CD.

Arthritis Rheum. 2010 Nov;62(11):3265-76. doi: 10.1002/art.27688.

13.

ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis.

Homer CR, Richmond AL, Rebert NA, Achkar JP, McDonald C.

Gastroenterology. 2010 Nov;139(5):1630-41, 1641.e1-2. doi: 10.1053/j.gastro.2010.07.006.

14.

The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis.

Alcina A, Vandenbroeck K, Otaegui D, Saiz A, Gonzalez JR, Fernandez O, Cavanillas ML, Cénit MC, Arroyo R, Alloza I, García-Barcina M, Antigüedad A, Leyva L, Izquierdo G, Lucas M, Fedetz M, Pinto-Medel MJ, Olascoaga J, Blanco Y, Comabella M, Montalban X, Urcelay E, Matesanz F.

Genes Immun. 2010 Jul;11(5):439-45. doi: 10.1038/gene.2010.30.

PMID:
20508602
15.

Recent advances in the genetics of systemic lupus erythematosus.

Flesher DL, Sun X, Behrens TW, Graham RR, Criswell LA.

Expert Rev Clin Immunol. 2010 May;6(3):461-79. doi: 10.1586/eci.10.8. Review.

16.

Tumor necrosis factor and anti-tumor necrosis factor therapies.

Keystone EC, Ware CF.

J Rheumatol Suppl. 2010 May;85:27-39. doi: 10.3899/jrheum.091463. Review.

PMID:
20436163
17.

Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects.

Wang K, Baldassano R, Zhang H, Qu HQ, Imielinski M, Kugathasan S, Annese V, Dubinsky M, Rotter JI, Russell RK, Bradfield JP, Sleiman PM, Glessner JT, Walters T, Hou C, Kim C, Frackelton EC, Garris M, Doran J, Romano C, Catassi C, Van Limbergen J, Guthery SL, Denson L, Piccoli D, Silverberg MS, Stanley CA, Monos D, Wilson DC, Griffiths A, Grant SF, Satsangi J, Polychronakos C, Hakonarson H.

Hum Mol Genet. 2010 May 15;19(10):2059-67. doi: 10.1093/hmg/ddq078.

18.

Recent advances in the genetics of rheumatoid arthritis.

Raychaudhuri S.

Curr Opin Rheumatol. 2010 Mar;22(2):109-18. doi: 10.1097/BOR.0b013e328336474d. Review.

19.

Autoimmune disease classification by inverse association with SNP alleles.

Sirota M, Schaub MA, Batzoglou S, Robinson WH, Butte AJ.

PLoS Genet. 2009 Dec;5(12):e1000792. doi: 10.1371/journal.pgen.1000792.

20.

The geoepidemiology of systemic lupus erythematosus.

Borchers AT, Naguwa SM, Shoenfeld Y, Gershwin ME.

Autoimmun Rev. 2010 Mar;9(5):A277-87. doi: 10.1016/j.autrev.2009.12.008. Review.

PMID:
20036343
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