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Heterogeneity of bronchitis in airway diseases in tertiary care clinical practice.

D'silva L, Hassan N, Wang HY, Kjarsgaard M, Efthimiadis A, Hargreave FE, Nair P.

Can Respir J. 2011 May-Jun;18(3):144-8.


Therapeutic strategies to reduce asthma exacerbations.

O'Byrne PM.

J Allergy Clin Immunol. 2011 Aug;128(2):257-63; quiz 264-5. doi: 10.1016/j.jaci.2011.03.035. Epub 2011 Apr 29. Review.


Targeting eosinophil biology in asthma therapy.

Wegmann M.

Am J Respir Cell Mol Biol. 2011 Oct;45(4):667-74. doi: 10.1165/rcmb.2011-0013TR. Epub 2011 Apr 7. Review.


Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis.

Wu D, Molofsky AB, Liang HE, Ricardo-Gonzalez RR, Jouihan HA, Bando JK, Chawla A, Locksley RM.

Science. 2011 Apr 8;332(6026):243-7. doi: 10.1126/science.1201475. Epub 2011 Mar 24.


Costs of asthma in the United States: 2002-2007.

Barnett SB, Nurmagambetov TA.

J Allergy Clin Immunol. 2011 Jan;127(1):145-52. doi: 10.1016/j.jaci.2010.10.020.


Tiotropium bromide step-up therapy for adults with uncontrolled asthma.

Peters SP, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger L, Engle LL, DiMango EA, Fahy JV, Israel E, Jarjour N, Kazani SD, Kraft M, Lazarus SC, Lemanske RF Jr, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Bleecker ER; National Heart, Lung, and Blood Institute Asthma Clinical Research Network.

N Engl J Med. 2010 Oct 28;363(18):1715-26. doi: 10.1056/NEJMoa1008770. Epub 2010 Sep 19.


A trial of clarithromycin for the treatment of suboptimally controlled asthma.

Sutherland ER, King TS, Icitovic N, Ameredes BT, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Chinchilli VM, Craig TJ, Denlinger L, DiMango EA, Fahy JV, Israel E, Jarjour N, Kraft M, Lazarus SC, Lemanske RF Jr, Peters SP, Ramsdell J, Sorkness CA, Szefler SJ, Walter MJ, Wasserman SI, Wechsler ME, Chu HW, Martin RJ; National Heart, Lung and Blood Institute's Asthma Clinical Research Network.

J Allergy Clin Immunol. 2010 Oct;126(4):747-53. doi: 10.1016/j.jaci.2010.07.024.


IgE sensitization to Aspergillus fumigatus is associated with reduced lung function in asthma.

Fairs A, Agbetile J, Hargadon B, Bourne M, Monteiro WR, Brightling CE, Bradding P, Green RH, Mutalithas K, Desai D, Pavord ID, Wardlaw AJ, Pashley CH.

Am J Respir Crit Care Med. 2010 Dec 1;182(11):1362-8. doi: 10.1164/rccm.201001-0087OC. Epub 2010 Jul 16.


Inflammatory phenotypes in adult asthma: clinical applications.

Gibson PG.

Clin Respir J. 2009 Oct;3(4):198-206. doi: 10.1111/j.1752-699X.2009.00162.x. Review.


Prevalence and trends in obesity among US adults, 1999-2008.

Flegal KM, Carroll MD, Ogden CL, Curtin LR.

JAMA. 2010 Jan 20;303(3):235-41. doi: 10.1001/jama.2009.2014. Epub 2010 Jan 13.


Effects of steroid therapy on inflammatory cell subtypes in asthma.

Cowan DC, Cowan JO, Palmay R, Williamson A, Taylor DR.

Thorax. 2010 May;65(5):384-90. doi: 10.1136/thx.2009.126722. Epub 2009 Dec 8.


Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program.

Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D'Agostino R Jr, Castro M, Curran-Everett D, Fitzpatrick AM, Gaston B, Jarjour NN, Sorkness R, Calhoun WJ, Chung KF, Comhair SA, Dweik RA, Israel E, Peters SP, Busse WW, Erzurum SC, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program.

Am J Respir Crit Care Med. 2010 Feb 15;181(4):315-23. doi: 10.1164/rccm.200906-0896OC. Epub 2009 Nov 5.


Consistency of sputum eosinophilia in difficult-to-treat asthma: a 5-year follow-up study.

van Veen IH, Ten Brinke A, Gauw SA, Sterk PJ, Rabe KF, Bel EH.

J Allergy Clin Immunol. 2009 Sep;124(3):615-7, 617.e1-2. doi: 10.1016/j.jaci.2009.06.029. No abstract available.


Body mass index and phenotype in subjects with mild-to-moderate persistent asthma.

Sutherland ER, Lehman EB, Teodorescu M, Wechsler ME; National Heart, Lung, and Blood Institute's Asthma Clinical Research Network.

J Allergy Clin Immunol. 2009 Jun;123(6):1328-34.e1. doi: 10.1016/j.jaci.2009.04.005.


T-helper type 2-driven inflammation defines major subphenotypes of asthma.

Woodruff PG, Modrek B, Choy DF, Jia G, Abbas AR, Ellwanger A, Koth LL, Arron JR, Fahy JV.

Am J Respir Crit Care Med. 2009 Sep 1;180(5):388-95. doi: 10.1164/rccm.200903-0392OC. Epub 2009 May 29. Erratum in: Am J Respir Crit Care Med. 2009 Oct 15;180(8):796.


Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease.

Anderson GP.

Lancet. 2008 Sep 20;372(9643):1107-19. doi: 10.1016/S0140-6736(08)61452-X. Review.


The association between obesity and asthma: interactions between systemic and airway inflammation.

Sutherland TJ, Cowan JO, Young S, Goulding A, Grant AM, Williamson A, Brassett K, Herbison GP, Taylor DR.

Am J Respir Crit Care Med. 2008 Sep 1;178(5):469-75. doi: 10.1164/rccm.200802-301OC. Epub 2008 Jun 19.


Cluster analysis and clinical asthma phenotypes.

Haldar P, Pavord ID, Shaw DE, Berry MA, Thomas M, Brightling CE, Wardlaw AJ, Green RH.

Am J Respir Crit Care Med. 2008 Aug 1;178(3):218-224. doi: 10.1164/rccm.200711-1754OC. Epub 2008 May 14.


Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007.

National Asthma Education and Prevention Program.

J Allergy Clin Immunol. 2007 Nov;120(5 Suppl):S94-138. Erratum in: J Allergy Clin Immunol. 2008 Jun;121(6):1330.


Association between neutrophilic airway inflammation and airflow limitation in adults with asthma.

Shaw DE, Berry MA, Hargadon B, McKenna S, Shelley MJ, Green RH, Brightling CE, Wardlaw AJ, Pavord ID.

Chest. 2007 Dec;132(6):1871-5. Epub 2007 Oct 9.


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