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Items: 1 to 20 of 42

1.

Myeloid C-type lectin receptors in pathogen recognition and host defense.

Osorio F, Reis e Sousa C.

Immunity. 2011 May 27;34(5):651-64. doi: 10.1016/j.immuni.2011.05.001. Review.

2.

Syk-coupled C-type lectins in immunity.

Kerrigan AM, Brown GD.

Trends Immunol. 2011 Apr;32(4):151-6. doi: 10.1016/j.it.2011.01.002. Epub 2011 Feb 18. Review.

3.

Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses.

Ritter M, Gross O, Kays S, Ruland J, Nimmerjahn F, Saijo S, Tschopp J, Layland LE, Prazeres da Costa C.

Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20459-64. doi: 10.1073/pnas.1010337107. Epub 2010 Nov 8.

4.

Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans.

Saijo S, Ikeda S, Yamabe K, Kakuta S, Ishigame H, Akitsu A, Fujikado N, Kusaka T, Kubo S, Chung SH, Komatsu R, Miura N, Adachi Y, Ohno N, Shibuya K, Yamamoto N, Kawakami K, Yamasaki S, Saito T, Akira S, Iwakura Y.

Immunity. 2010 May 28;32(5):681-91. doi: 10.1016/j.immuni.2010.05.001. Epub 2010 May 20.

5.

The SYK tyrosine kinase: a crucial player in diverse biological functions.

Mócsai A, Ruland J, Tybulewicz VL.

Nat Rev Immunol. 2010 Jun;10(6):387-402. doi: 10.1038/nri2765. Review.

6.

Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene.

Pointon JJ, Harvey D, Karaderi T, Appleton LH, Farrar C, Stone MA, Sturrock RD, Brown MA, Wordsworth BP.

Genes Immun. 2010 Sep;11(6):490-6. doi: 10.1038/gene.2010.17. Epub 2010 May 13. Erratum in: Genes Immun. 2011 Jun;12(4):319-20.

7.

The adaptor molecule CARD9 is essential for tuberculosis control.

Dorhoi A, Desel C, Yeremeev V, Pradl L, Brinkmann V, Mollenkopf HJ, Hanke K, Gross O, Ruland J, Kaufmann SH.

J Exp Med. 2010 Apr 12;207(4):777-92. doi: 10.1084/jem.20090067. Epub 2010 Mar 29.

8.

Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate.

Schoenen H, Bodendorfer B, Hitchens K, Manzanero S, Werninghaus K, Nimmerjahn F, Agger EM, Stenger S, Andersen P, Ruland J, Brown GD, Wells C, Lang R.

J Immunol. 2010 Mar 15;184(6):2756-60. doi: 10.4049/jimmunol.0904013. Epub 2010 Feb 17.

9.

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle.

Ishikawa E, Ishikawa T, Morita YS, Toyonaga K, Yamada H, Takeuchi O, Kinoshita T, Akira S, Yoshikai Y, Yamasaki S.

J Exp Med. 2009 Dec 21;206(13):2879-88. doi: 10.1084/jem.20091750. Epub 2009 Dec 14.

10.

Human dectin-1 deficiency and mucocutaneous fungal infections.

Ferwerda B, Ferwerda G, Plantinga TS, Willment JA, van Spriel AB, Venselaar H, Elbers CC, Johnson MD, Cambi A, Huysamen C, Jacobs L, Jansen T, Verheijen K, Masthoff L, Morré SA, Vriend G, Williams DL, Perfect JR, Joosten LA, Wijmenga C, van der Meer JW, Adema GJ, Kullberg BJ, Brown GD, Netea MG.

N Engl J Med. 2009 Oct 29;361(18):1760-7. doi: 10.1056/NEJMoa0901053.

11.

A homozygous CARD9 mutation in a family with susceptibility to fungal infections.

Glocker EO, Hennigs A, Nabavi M, Schäffer AA, Woellner C, Salzer U, Pfeifer D, Veelken H, Warnatz K, Tahami F, Jamal S, Manguiat A, Rezaei N, Amirzargar AA, Plebani A, Hannesschläger N, Gross O, Ruland J, Grimbacher B.

N Engl J Med. 2009 Oct 29;361(18):1727-35. doi: 10.1056/NEJMoa0810719.

12.

Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes.

Choudhary C, Olsen JV, Brandts C, Cox J, Reddy PN, Böhmer FD, Gerke V, Schmidt-Arras DE, Berdel WE, Müller-Tidow C, Mann M, Serve H.

Mol Cell. 2009 Oct 23;36(2):326-39. doi: 10.1016/j.molcel.2009.09.019.

13.

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection.

Robinson MJ, Osorio F, Rosas M, Freitas RP, Schweighoffer E, Gross O, Verbeek JS, Ruland J, Tybulewicz V, Brown GD, Moita LF, Taylor PR, Reis e Sousa C.

J Exp Med. 2009 Aug 31;206(9):2037-51. doi: 10.1084/jem.20082818. Epub 2009 Aug 24.

14.

Approaching the asymptote: 20 years later.

Medzhitov R.

Immunity. 2009 Jun 19;30(6):766-75. doi: 10.1016/j.immuni.2009.06.004.

15.

Regulation and function of NF-kappaB transcription factors in the immune system.

Vallabhapurapu S, Karin M.

Annu Rev Immunol. 2009;27:693-733. doi: 10.1146/annurev.immunol.021908.132641. Review.

PMID:
19302050
16.

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity.

Sancho D, Joffre OP, Keller AM, Rogers NC, Martínez D, Hernanz-Falcón P, Rosewell I, Reis e Sousa C.

Nature. 2009 Apr 16;458(7240):899-903. doi: 10.1038/nature07750.

17.

Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation.

Werninghaus K, Babiak A, Gross O, Hölscher C, Dietrich H, Agger EM, Mages J, Mocsai A, Schoenen H, Finger K, Nimmerjahn F, Brown GD, Kirschning C, Heit A, Andersen P, Wagner H, Ruland J, Lang R.

J Exp Med. 2009 Jan 16;206(1):89-97. doi: 10.1084/jem.20081445. Epub 2009 Jan 12.

18.

Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells.

Xu S, Huo J, Lee KG, Kurosaki T, Lam KP.

J Biol Chem. 2009 Mar 13;284(11):7038-46. doi: 10.1074/jbc.M806650200. Epub 2009 Jan 9.

19.

Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-kappaB activation through Raf-1 and Syk.

Gringhuis SI, den Dunnen J, Litjens M, van der Vlist M, Wevers B, Bruijns SC, Geijtenbeek TB.

Nat Immunol. 2009 Feb;10(2):203-13. doi: 10.1038/ni.1692. Epub 2009 Jan 4.

PMID:
19122653
20.

Mincle is an ITAM-coupled activating receptor that senses damaged cells.

Yamasaki S, Ishikawa E, Sakuma M, Hara H, Ogata K, Saito T.

Nat Immunol. 2008 Oct;9(10):1179-88. doi: 10.1038/ni.1651. Epub 2008 Sep 7.

PMID:
18776906

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