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Items: 1 to 20 of 48

1.

Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia.

Johansen CT, Wang J, McIntyre AD, Martins RA, Ban MR, Lanktree MB, Huff MW, Péterfy M, Mehrabian M, Lusis AJ, Kathiresan S, Anand SS, Yusuf S, Lee AH, Glimcher LH, Cao H, Hegele RA.

Circ Cardiovasc Genet. 2012 Feb 1;5(1):66-72. doi: 10.1161/CIRCGENETICS.111.960864.

2.

Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice.

Zhang C, Wang G, Zheng Z, Maddipati KR, Zhang X, Dyson G, Williams P, Duncan SA, Kaufman RJ, Zhang K.

Hepatology. 2012 Apr;55(4):1070-82. doi: 10.1002/hep.24783.

3.
4.

The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism.

Lee JH, Giannikopoulos P, Duncan SA, Wang J, Johansen CT, Brown JD, Plutzky J, Hegele RA, Glimcher LH, Lee AH.

Nat Med. 2011 Jun 12;17(7):812-5. doi: 10.1038/nm.2347.

5.

Testing for rare variant associations in complex diseases.

Asimit J, Zeggini E.

Genome Med. 2009;1(11):24. doi: 10.1186/gm238.

6.

Genetic bases of hypertriglyceridemic phenotypes.

Johansen CT, Hegele RA.

Curr Opin Lipidol. 2011 Aug;22(4):247-53. doi: 10.1097/MOL.0b013e3283471972. Review.

PMID:
21519249
7.

The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology.

Asada R, Kanemoto S, Kondo S, Saito A, Imaizumi K.

J Biochem. 2011 May;149(5):507-18. doi: 10.1093/jb/mvr041. Review.

PMID:
21454302
8.

Endocannabinoids in liver disease.

Tam J, Liu J, Mukhopadhyay B, Cinar R, Godlewski G, Kunos G.

Hepatology. 2011 Jan;53(1):346-55. doi: 10.1002/hep.24077. Review.

9.

HNF4α--role in drug metabolism and potential drug target?

Hwang-Verslues WW, Sladek FM.

Curr Opin Pharmacol. 2010 Dec;10(6):698-705. doi: 10.1016/j.coph.2010.08.010. Review.

10.

Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin.

Gentile CL, Wang D, Pfaffenbach KT, Cox R, Wei Y, Pagliassotti MJ.

Mol Cell Biochem. 2010 Nov;344(1-2):99-107. doi: 10.1007/s11010-010-0533-3.

11.

Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH.

Lee MW, Chanda D, Yang J, Oh H, Kim SS, Yoon YS, Hong S, Park KG, Lee IK, Choi CS, Hanson RW, Choi HS, Koo SH.

Cell Metab. 2010 Apr 7;11(4):331-9. doi: 10.1016/j.cmet.2010.02.016.

12.

N-linked glycosylation is required for optimal proteolytic activation of membrane-bound transcription factor CREB-H.

Chan CP, Mak TY, Chin KT, Ng IO, Jin DY.

J Cell Sci. 2010 May 1;123(Pt 9):1438-48. doi: 10.1242/jcs.067819.

13.

The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha.

Danno H, Ishii KA, Nakagawa Y, Mikami M, Yamamoto T, Yabe S, Furusawa M, Kumadaki S, Watanabe K, Shimizu H, Matsuzaka T, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Yamada N, Shimano H.

Biochem Biophys Res Commun. 2010 Jan 8;391(2):1222-7. doi: 10.1016/j.bbrc.2009.12.046.

PMID:
20006574
14.

Fibroblast growth factor 21: from pharmacology to physiology.

Kliewer SA, Mangelsdorf DJ.

Am J Clin Nutr. 2010 Jan;91(1):254S-257S. doi: 10.3945/ajcn.2009.28449B. Review.

15.

ER stress controls iron metabolism through induction of hepcidin.

Vecchi C, Montosi G, Zhang K, Lamberti I, Duncan SA, Kaufman RJ, Pietrangelo A.

Science. 2009 Aug 14;325(5942):877-80. doi: 10.1126/science.1176639.

16.

CIDE proteins and metabolic disorders.

Gong J, Sun Z, Li P.

Curr Opin Lipidol. 2009 Apr;20(2):121-6. doi: 10.1097/MOL.0b013e328328d0bb. Review.

PMID:
19276890
17.

Plasma lipoproteins: genetic influences and clinical implications.

Hegele RA.

Nat Rev Genet. 2009 Feb;10(2):109-21. doi: 10.1038/nrg2481. Review.

PMID:
19139765
18.

Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL.

Brown MS, Goldstein JL.

J Lipid Res. 2009 Apr;50 Suppl:S15-27. doi: 10.1194/jlr.R800054-JLR200. Review.

19.

Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H.

Luebke-Wheeler J, Zhang K, Battle M, Si-Tayeb K, Garrison W, Chhinder S, Li J, Kaufman RJ, Duncan SA.

Hepatology. 2008 Oct;48(4):1242-50. doi: 10.1002/hep.22439.

20.

The endoplasmic reticulum stress response in immunity and autoimmunity.

Todd DJ, Lee AH, Glimcher LH.

Nat Rev Immunol. 2008 Sep;8(9):663-74. doi: 10.1038/nri2359. Review.

PMID:
18670423
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