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Items: 1 to 20 of 207

1.

Genetic variants associated with persistent central obesity and the metabolic syndrome in a 12-year longitudinal study.

Cheung CY, Tso AW, Cheung BM, Xu A, Ong KL, Law LS, Wat NM, Janus ED, Sham PC, Lam KS.

Eur J Endocrinol. 2011 Mar;164(3):381-8. doi: 10.1530/EJE-10-0902. Epub 2010 Dec 8.

2.

Gene-lifestyle and gene-pharmacotherapy interactions in obesity and its cardiovascular consequences.

Franks PW, Poveda A.

Curr Vasc Pharmacol. 2011 Jul 1;9(4):401-56. Review.

PMID:
21143160
3.

A map of human genome variation from population-scale sequencing.

1000 Genomes Project Consortium, Abecasis GR, Altshuler D, Auton A, Brooks LD, Durbin RM, Gibbs RA, Hurles ME, McVean GA.

Nature. 2010 Oct 28;467(7319):1061-73. doi: 10.1038/nature09534. Erratum in: Nature. 2011 May 26;473(7348):544. Xue, Yali [added]; Cartwright, Reed A [added]; Altshuler, David L [corrected to Altshuler, David]; Kebbel, Andrew [corrected to Keebler, Jonathan]; Koko-Gonzales, Paula [corrected to Kokko-Gonzales, Paula]; Nickerson, Debbie A [corrected to Nickerson, Deborah A].

4.

Clinicopathologic correlation of choroidal and retinal neovascular lesions in age-related macular degeneration.

Klein ML, Wilson DJ.

Am J Ophthalmol. 2011 Jan;151(1):161-9. doi: 10.1016/j.ajo.2010.07.020.

PMID:
20970772
5.

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants.

Li Y, Vinckenbosch N, Tian G, Huerta-Sanchez E, Jiang T, Jiang H, Albrechtsen A, Andersen G, Cao H, Korneliussen T, Grarup N, Guo Y, Hellman I, Jin X, Li Q, Liu J, Liu X, Sparsø T, Tang M, Wu H, Wu R, Yu C, Zheng H, Astrup A, Bolund L, Holmkvist J, Jørgensen T, Kristiansen K, Schmitz O, Schwartz TW, Zhang X, Li R, Yang H, Wang J, Hansen T, Pedersen O, Nielsen R, Wang J.

Nat Genet. 2010 Nov;42(11):969-72. doi: 10.1038/ng.680. Epub 2010 Oct 3.

PMID:
20890277
6.

Pharmacogenetic aspects in therapeutic management of subfoveal choroidal neovascularisation: role of factor XIII-A 185 T-allele.

Parmeggiani F, Costagliola C, Incorvaia C, Sebastiani A, Gemmati D.

Curr Drug Targets. 2011 Feb;12(2):138-48. Review.

PMID:
20887247
7.

Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration.

Kopplin LJ, Igo RP Jr, Wang Y, Sivakumaran TA, Hagstrom SA, Peachey NS, Francis PJ, Klein ML, SanGiovanni JP, Chew EY, Pauer GJ, Sturgill GM, Joshi T, Tian L, Xi Q, Henning AK, Lee KE, Klein R, Klein BE, Iyengar SK.

Genes Immun. 2010 Dec;11(8):609-21. doi: 10.1038/gene.2010.39. Epub 2010 Sep 23.

8.

Vascular endothelial growth factor gene polymorphisms and risk of neovascular age-related macular degeneration in a Chinese cohort.

Qu Y, Dai H, Zhou F, Zhang X, Xu X, Zhang X, Bi H, Pan X, Wang H, Jiang H, Yin N, Dang G.

Ophthalmic Res. 2011;45(3):142-8. doi: 10.1159/000319543. Epub 2010 Sep 17.

PMID:
20847577
9.

Differential arginylation of actin isoforms is regulated by coding sequence-dependent degradation.

Zhang F, Saha S, Shabalina SA, Kashina A.

Science. 2010 Sep 17;329(5998):1534-7. doi: 10.1126/science.1191701.

10.

N-Acetyltransferase-2 (NAT2) gene polymorphisms and enzyme activity in Serbs: unprecedented high prevalence of rapid acetylators in a White population.

Djordjevic N, Carrillo JA, Ueda N, Gervasini G, Fukasawa T, Suda A, Jankovic S, Aklillu E.

J Clin Pharmacol. 2011 Jul;51(7):994-1003. doi: 10.1177/0091270010377630. Epub 2010 Aug 27.

PMID:
20801937
11.
12.

A subretinal matrigel rat choroidal neovascularization (CNV) model and inhibition of CNV and associated inflammation and fibrosis by VEGF trap.

Cao J, Zhao L, Li Y, Liu Y, Xiao W, Song Y, Luo L, Huang D, Yancopoulos GD, Wiegand SJ, Wen R.

Invest Ophthalmol Vis Sci. 2010 Nov;51(11):6009-17. doi: 10.1167/iovs.09-4956. Epub 2010 Jun 10.

13.

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.

Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL; Complications of Age-Related Macular Degeneration Prevention Trial Research Group, Brucker AJ, Orlin A, Brown G, Ho A, Regillo C, Donoso L, Tian L, Kaderli B, Hadley D, Hagstrom SA, Peachey NS, Klein R, Klein BE, Gotoh N, Yamashiro K, Ferris Iii F, Fagerness JA, Reynolds R, Farrer LA, Kim IK, Miller JW, Cortón M, Carracedo A, Sanchez-Salorio M, Pugh EW, Doheny KF, Brion M, Deangelis MM, Weeks DE, Zack DJ, Chew EY, Heckenlively JR, Yoshimura N, Iyengar SK, Francis PJ, Katsanis N, Seddon JM, Haines JL, Gorin MB, Abecasis GR, Swaroop A.

Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7401-6. doi: 10.1073/pnas.0912702107. Epub 2010 Apr 12.

14.

Three major loci involved in age-related macular degeneration are also associated with polypoidal choroidal vasculopathy.

Lima LH, Schubert C, Ferrara DC, Merriam JE, Imamura Y, Freund KB, Spaide RF, Yannuzzi LA, Allikmets R.

Ophthalmology. 2010 Aug;117(8):1567-70. doi: 10.1016/j.ophtha.2009.12.018. Epub 2010 Apr 8.

15.

Photodynamic therapy alone versus combined with intravitreal bevacizumab for neovascular age-related macular degeneration without polypoidal choroidal vasculopathy in Japanese patients.

Hara R, Kawaji T, Inomata Y, Tahara J, Sagara N, Fukushima M, Tanihara H.

Graefes Arch Clin Exp Ophthalmol. 2010 Jul;248(7):931-6. doi: 10.1007/s00417-010-1343-8. Epub 2010 Mar 10.

PMID:
20221623
16.

Induction of interleukin-8 gene expression and protein secretion by C-reactive protein in ARPE-19 cells.

Wang Y, Bian ZM, Yu WZ, Yan Z, Chen WC, Li XX.

Exp Eye Res. 2010 Aug;91(2):135-42. doi: 10.1016/j.exer.2010.02.008. Epub 2010 Feb 23.

PMID:
20188089
17.

Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration.

Wang G, Spencer KL, Scott WK, Whitehead P, Court BL, Ayala-Haedo J, Mayo P, Schwartz SG, Kovach JL, Gallins P, Polk M, Agarwal A, Postel EA, Haines JL, Pericak-Vance MA.

Hum Genet. 2010 Mar;127(5):595-602. doi: 10.1007/s00439-010-0805-8. Epub 2010 Feb 25.

18.

Polymorphisms in the VEGFA and VEGFR-2 genes and neovascular age-related macular degeneration.

Fang AM, Lee AY, Kulkarni M, Osborn MP, Brantley MA Jr.

Mol Vis. 2009 Dec 10;15:2710-9.

19.
20.

Association of c3 gene polymorphisms with neovascular age-related macular degeneration in a chinese population.

Pei XT, Li XX, Bao YZ, Yu WZ, Yan Z, Qi HJ, Qian T, Xiao HX.

Curr Eye Res. 2009 Aug;34(8):615-22.

PMID:
19899988

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