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Items: 1 to 20 of 43


Mthfs is an Essential Gene in Mice and a Component of the Purinosome.

Field MS, Anderson DD, Stover PJ.

Front Genet. 2011 Jun 20;2:36. doi: 10.3389/fgene.2011.00036. eCollection 2011.


Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA.

MacFarlane AJ, Anderson DD, Flodby P, Perry CA, Allen RH, Stabler SP, Stover PJ.

J Biol Chem. 2011 Dec 23;286(51):44015-22. doi: 10.1074/jbc.M111.307629. Epub 2011 Nov 4.


Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria.

Anderson DD, Quintero CM, Stover PJ.

Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15163-8. doi: 10.1073/pnas.1103623108. Epub 2011 Aug 26.


Histone demethylase LSD1 is a folate-binding protein.

Luka Z, Moss F, Loukachevitch LV, Bornhop DJ, Wagner C.

Biochemistry. 2011 May 31;50(21):4750-6. doi: 10.1021/bi200247b. Epub 2011 May 5.


Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk.

Macfarlane AJ, Perry CA, McEntee MF, Lin DM, Stover PJ.

Cancer Res. 2011 Mar 15;71(6):2098-107. doi: 10.1158/0008-5472.CAN-10-1886.


Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice.

Beaudin AE, Abarinov EV, Noden DM, Perry CA, Chu S, Stabler SP, Allen RH, Stover PJ.

Am J Clin Nutr. 2011 Apr;93(4):789-98. doi: 10.3945/ajcn.110.002766. Epub 2011 Feb 23.


Compartmentalization of Mammalian folate-mediated one-carbon metabolism.

Tibbetts AS, Appling DR.

Annu Rev Nutr. 2010 Aug 21;30:57-81. doi: 10.1146/annurev.nutr.012809.104810. Review.


Microtubule-assisted mechanism for functional metabolic macromolecular complex formation.

An S, Deng Y, Tomsho JW, Kyoung M, Benkovic SJ.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):12872-6. doi: 10.1073/pnas.1008451107. Epub 2010 Jul 6.


Dynamic regulation of a metabolic multi-enzyme complex by protein kinase CK2.

An S, Kyoung M, Allen JJ, Shokat KM, Benkovic SJ.

J Biol Chem. 2010 Apr 9;285(15):11093-9. doi: 10.1074/jbc.M110.101139. Epub 2010 Feb 15.


A UV-responsive internal ribosome entry site enhances serine hydroxymethyltransferase 1 expression for DNA damage repair.

Fox JT, Shin WK, Caudill MA, Stover PJ.

J Biol Chem. 2009 Nov 6;284(45):31097-108. doi: 10.1074/jbc.M109.015800. Epub 2009 Sep 4.


SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis.

Anderson DD, Stover PJ.

PLoS One. 2009 Jun 9;4(6):e5839. doi: 10.1371/journal.pone.0005839.


Regulating post-translational modifications of the eukaryotic replication clamp PCNA.

Ulrich HD.

DNA Repair (Amst). 2009 Apr 5;8(4):461-9. doi: 10.1016/j.dnarep.2009.01.006. Epub 2009 Feb 13. Review.


Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources.

Huang da W, Sherman BT, Lempicki RA.

Nat Protoc. 2009;4(1):44-57. doi: 10.1038/nprot.2008.211.


Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists.

Huang da W, Sherman BT, Lempicki RA.

Nucleic Acids Res. 2009 Jan;37(1):1-13. doi: 10.1093/nar/gkn923. Epub 2008 Nov 25.


Folate-mediated one-carbon metabolism.

Fox JT, Stover PJ.

Vitam Horm. 2008;79:1-44. doi: 10.1016/S0083-6729(08)00401-9.


Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice.

MacFarlane AJ, Liu X, Perry CA, Flodby P, Allen RH, Stabler SP, Stover PJ.

J Biol Chem. 2008 Sep 19;283(38):25846-53. doi: 10.1074/jbc.M802671200. Epub 2008 Jul 21.


The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication.

Shumaker DK, Solimando L, Sengupta K, Shimi T, Adam SA, Grunwald A, Strelkov SV, Aebi U, Cardoso MC, Goldman RD.

J Cell Biol. 2008 Apr 21;181(2):269-80. doi: 10.1083/jcb.200708155.


Reversible compartmentalization of de novo purine biosynthetic complexes in living cells.

An S, Kumar R, Sheets ED, Benkovic SJ.

Science. 2008 Apr 4;320(5872):103-6. doi: 10.1126/science.1152241.


Small ubiquitin-like modifier-1 (SUMO-1) modification of thymidylate synthase and dihydrofolate reductase.

Anderson DD, Woeller CF, Stover PJ.

Clin Chem Lab Med. 2007;45(12):1760-3.


PCNA, the maestro of the replication fork.

Moldovan GL, Pfander B, Jentsch S.

Cell. 2007 May 18;129(4):665-79. Review.

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