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Items: 1 to 20 of 58


Diabetes and breast cancer among women with BRCA1 and BRCA2 mutations.

Bordeleau L, Lipscombe L, Lubinski J, Ghadirian P, Foulkes WD, Neuhausen S, Ainsworth P, Pollak M, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group.

Cancer. 2011 May 1;117(9):1812-8. doi: 10.1002/cncr.25595. Epub 2010 Nov 10.


Inhibition of p53 after acute myocardial infarction: reduction of apoptosis is counteracted by disturbed scar formation and cardiac rupture.

Zhang Y, Köhler K, Xu J, Lu D, Braun T, Schlitt A, Buerke M, Müller-Werdan U, Werdan K, Ebelt H.

J Mol Cell Cardiol. 2011 Mar;50(3):471-8. doi: 10.1016/j.yjmcc.2010.11.006. Epub 2010 Nov 11.


Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury.

Naito AT, Okada S, Minamino T, Iwanaga K, Liu ML, Sumida T, Nomura S, Sahara N, Mizoroki T, Takashima A, Akazawa H, Nagai T, Shiojima I, Komuro I.

Circ Res. 2010 Jun 11;106(11):1692-702. doi: 10.1161/CIRCRESAHA.109.214346. Epub 2010 Apr 22.


The DNA-damage response in human biology and disease.

Jackson SP, Bartek J.

Nature. 2009 Oct 22;461(7267):1071-8. doi: 10.1038/nature08467. Review.


A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.

Cao L, Xu X, Bunting SF, Liu J, Wang RH, Cao LL, Wu JJ, Peng TN, Chen J, Nussenzweig A, Deng CX, Finkel T.

Mol Cell. 2009 Aug 28;35(4):534-41. doi: 10.1016/j.molcel.2009.06.037.


Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity.

Yoshida M, Shiojima I, Ikeda H, Komuro I.

J Mol Cell Cardiol. 2009 Nov;47(5):698-705. doi: 10.1016/j.yjmcc.2009.07.024. Epub 2009 Aug 3.


Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and management.

Yeh ET, Bickford CL.

J Am Coll Cardiol. 2009 Jun 16;53(24):2231-47. doi: 10.1016/j.jacc.2009.02.050. Review.


Lack of S100A1 in mice confers a gender-dependent hypertensive phenotype and increased mortality after myocardial infarction.

Desjardins JF, Pourdjabbar A, Quan A, Leong-Poi H, Teichert-Kuliszewska K, Verma S, Parker TG.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1457-65. doi: 10.1152/ajpheart.00088.2008. Epub 2009 Mar 13.


Potential excess mortality in BRCA1/2 mutation carriers beyond breast, ovarian, prostate, and pancreatic cancers, and melanoma.

Mai PL, Chatterjee N, Hartge P, Tucker M, Brody L, Struewing JP, Wacholder S.

PLoS One. 2009;4(3):e4812. doi: 10.1371/journal.pone.0004812. Epub 2009 Mar 11.


GammaH2AX and cancer.

Bonner WM, Redon CE, Dickey JS, Nakamura AJ, Sedelnikova OA, Solier S, Pommier Y.

Nat Rev Cancer. 2008 Dec;8(12):957-67. doi: 10.1038/nrc2523. Epub 2008 Nov 13. Review.


Inherited susceptibility to common cancers.

Foulkes WD.

N Engl J Med. 2008 Nov 13;359(20):2143-53. doi: 10.1056/NEJMra0802968. Review. No abstract available.


Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network.

Greenberg RA.

Chromosoma. 2008 Aug;117(4):305-17. doi: 10.1007/s00412-008-0154-8. Epub 2008 Mar 28. Review.


Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress.

DeGeorge BR Jr, Gao E, Boucher M, Vinge LE, Martini JS, Raake PW, Chuprun JK, Harris DM, Kim GW, Soltys S, Eckhart AD, Koch WJ.

Circulation. 2008 Mar 18;117(11):1378-87. doi: 10.1161/CIRCULATIONAHA.107.752618. Epub 2008 Mar 3.


Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations.

Fackenthal JD, Olopade OI.

Nat Rev Cancer. 2007 Dec;7(12):937-48. Review.


Phosphorylation and translocation of heat shock protein 27 and alphaB-crystallin in human myocardium after cardioplegia and cardiopulmonary bypass.

Clements RT, Sodha NR, Feng J, Mieno S, Boodhwani M, Ramlawi B, Bianchi C, Sellke FW.

J Thorac Cardiovasc Surg. 2007 Dec;134(6):1461-70.


TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways.

Haudek SB, Taffet GE, Schneider MD, Mann DL.

J Clin Invest. 2007 Sep;117(9):2692-701.


Narrative review: cardiopulmonary resuscitation and emergency cardiovascular care: review of the current guidelines.

Ali B, Zafari AM.

Ann Intern Med. 2007 Aug 7;147(3):171-9. Review. Erratum in: Ann Intern Med. 2007 Oct 16;147(8):592.


RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites.

Sobhian B, Shao G, Lilli DR, Culhane AC, Moreau LA, Xia B, Livingston DM, Greenberg RA.

Science. 2007 May 25;316(5828):1198-202.


Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines.

Fazel S, Cimini M, Chen L, Li S, Angoulvant D, Fedak P, Verma S, Weisel RD, Keating A, Li RK.

J Clin Invest. 2006 Jul;116(7):1865-77.


Dilated cardiomyopathy resulting from high-level myocardial expression of Cre-recombinase.

Buerger A, Rozhitskaya O, Sherwood MC, Dorfman AL, Bisping E, Abel ED, Pu WT, Izumo S, Jay PY.

J Card Fail. 2006 Jun;12(5):392-8.


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