Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 192

1.

siRNA-mediated knockdown of aryl hydrocarbon receptor nuclear translocator 2 affects hypoxia-inducible factor-1 regulatory signaling and metabolism in human breast cancer cells.

Qin XY, Wei F, Yoshinaga J, Yonemoto J, Tanokura M, Sone H.

FEBS Lett. 2011 Oct 20;585(20):3310-5. doi: 10.1016/j.febslet.2011.09.017. Epub 2011 Sep 19.

2.

The SirT3 divining rod points to oxidative stress.

Bell EL, Guarente L.

Mol Cell. 2011 Jun 10;42(5):561-8. doi: 10.1016/j.molcel.2011.05.008. Review.

3.

The hypoxia-associated factor switches cells from HIF-1α- to HIF-2α-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion.

Koh MY, Lemos R Jr, Liu X, Powis G.

Cancer Res. 2011 Jun 1;71(11):4015-27. doi: 10.1158/0008-5472.CAN-10-4142. Epub 2011 Apr 21.

4.

Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia response.

Heikkilä M, Pasanen A, Kivirikko KI, Myllyharju J.

Cell Mol Life Sci. 2011 Dec;68(23):3885-901. doi: 10.1007/s00018-011-0679-5. Epub 2011 Apr 10.

PMID:
21479871
5.

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq.

Schödel J, Oikonomopoulos S, Ragoussis J, Pugh CW, Ratcliffe PJ, Mole DR.

Blood. 2011 Jun 9;117(23):e207-17. doi: 10.1182/blood-2010-10-314427. Epub 2011 Mar 29.

6.

SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization.

Finley LW, Carracedo A, Lee J, Souza A, Egia A, Zhang J, Teruya-Feldstein J, Moreira PI, Cardoso SM, Clish CB, Pandolfi PP, Haigis MC.

Cancer Cell. 2011 Mar 8;19(3):416-28. doi: 10.1016/j.ccr.2011.02.014.

8.

SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production.

Bell EL, Emerling BM, Ricoult SJ, Guarente L.

Oncogene. 2011 Jun 30;30(26):2986-96. doi: 10.1038/onc.2011.37. Epub 2011 Feb 28.

9.

Hypoxia increases sirtuin 1 expression in a hypoxia-inducible factor-dependent manner.

Chen R, Dioum EM, Hogg RT, Gerard RD, Garcia JA.

J Biol Chem. 2011 Apr 22;286(16):13869-78. doi: 10.1074/jbc.M110.175414. Epub 2011 Feb 23.

10.

Hypoxia-inducible factor α subunit stabilization by NEDD8 conjugation is reactive oxygen species-dependent.

Ryu JH, Li SH, Park HS, Park JW, Lee B, Chun YS.

J Biol Chem. 2011 Mar 4;286(9):6963-70. doi: 10.1074/jbc.M110.188706. Epub 2010 Dec 30.

11.

Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.

Purdue MP, Johansson M, Zelenika D, Toro JR, Scelo G, Moore LE, Prokhortchouk E, Wu X, Kiemeney LA, Gaborieau V, Jacobs KB, Chow WH, Zaridze D, Matveev V, Lubinski J, Trubicka J, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Bucur A, Bencko V, Foretova L, Janout V, Boffetta P, Colt JS, Davis FG, Schwartz KL, Banks RE, Selby PJ, Harnden P, Berg CD, Hsing AW, Grubb RL 3rd, Boeing H, Vineis P, Clavel-Chapelon F, Palli D, Tumino R, Krogh V, Panico S, Duell EJ, Quirós JR, Sanchez MJ, Navarro C, Ardanaz E, Dorronsoro M, Khaw KT, Allen NE, Bueno-de-Mesquita HB, Peeters PH, Trichopoulos D, Linseisen J, Ljungberg B, Overvad K, Tjønneland A, Romieu I, Riboli E, Mukeria A, Shangina O, Stevens VL, Thun MJ, Diver WR, Gapstur SM, Pharoah PD, Easton DF, Albanes D, Weinstein SJ, Virtamo J, Vatten L, Hveem K, Njølstad I, Tell GS, Stoltenberg C, Kumar R, Koppova K, Cussenot O, Benhamou S, Oosterwijk E, Vermeulen SH, Aben KK, van der Marel SL, Ye Y, Wood CG, Pu X, Mazur AM, Boulygina ES, Chekanov NN, Foglio M, Lechner D, Gut I, Heath S, Blanche H, Hutchinson A, Thomas G, Wang Z, Yeager M, Fraumeni JF Jr, Skryabin KG, McKay JD, Rothman N, Chanock SJ, Lathrop M, Brennan P.

Nat Genet. 2011 Jan;43(1):60-5. doi: 10.1038/ng.723. Epub 2010 Dec 5.

12.

mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.

Cam H, Easton JB, High A, Houghton PJ.

Mol Cell. 2010 Nov 24;40(4):509-20. doi: 10.1016/j.molcel.2010.10.030.

13.

Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress.

Sengupta S, Peterson TR, Sabatini DM.

Mol Cell. 2010 Oct 22;40(2):310-22. doi: 10.1016/j.molcel.2010.09.026. Review.

14.

Hypoxia-inducible factors and the response to hypoxic stress.

Majmundar AJ, Wong WJ, Simon MC.

Mol Cell. 2010 Oct 22;40(2):294-309. doi: 10.1016/j.molcel.2010.09.022. Review.

15.

Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha.

Qing G, Skuli N, Mayes PA, Pawel B, Martinez D, Maris JM, Simon MC.

Cancer Res. 2010 Dec 15;70(24):10351-61. doi: 10.1158/0008-5472.CAN-10-0740. Epub 2010 Oct 20.

16.

The HIF pathway and erythrocytosis.

Lee FS, Percy MJ.

Annu Rev Pathol. 2011;6:165-92. doi: 10.1146/annurev-pathol-011110-130321. Review.

PMID:
20939709
17.

O2 regulates stem cells through Wnt/β-catenin signalling.

Mazumdar J, O'Brien WT, Johnson RS, LaManna JC, Chavez JC, Klein PS, Simon MC.

Nat Cell Biol. 2010 Oct;12(10):1007-13. doi: 10.1038/ncb2102. Epub 2010 Sep 19.

18.

Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression.

Doedens AL, Stockmann C, Rubinstein MP, Liao D, Zhang N, DeNardo DG, Coussens LM, Karin M, Goldrath AW, Johnson RS.

Cancer Res. 2010 Oct 1;70(19):7465-75. doi: 10.1158/0008-5472.CAN-10-1439. Epub 2010 Sep 14.

19.

AKT-ing via microRNA.

Sayed D, Abdellatif M.

Cell Cycle. 2010 Aug 15;9(16):3213-7. doi: 10.4161/cc.9.16.12634. Epub 2010 Aug 10.

20.

Casein kinase 1 regulates human hypoxia-inducible factor HIF-1.

Kalousi A, Mylonis I, Politou AS, Chachami G, Paraskeva E, Simos G.

J Cell Sci. 2010 Sep 1;123(Pt 17):2976-86. doi: 10.1242/jcs.068122. Epub 2010 Aug 10.

Supplemental Content

Support Center