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Items: 1 to 20 of 73

1.

Generation of a mouse model of Von Hippel-Lindau kidney disease leading to renal cancers by expression of a constitutively active mutant of HIF1α.

Fu L, Wang G, Shevchuk MM, Nanus DM, Gudas LJ.

Cancer Res. 2011 Nov 1;71(21):6848-56. doi: 10.1158/0008-5472.CAN-11-1745. Epub 2011 Sep 9.

2.

Mutations in CIC and FUBP1 contribute to human oligodendroglioma.

Bettegowda C, Agrawal N, Jiao Y, Sausen M, Wood LD, Hruban RH, Rodriguez FJ, Cahill DP, McLendon R, Riggins G, Velculescu VE, Oba-Shinjo SM, Marie SK, Vogelstein B, Bigner D, Yan H, Papadopoulos N, Kinzler KW.

Science. 2011 Sep 9;333(6048):1453-5. doi: 10.1126/science.1210557. Epub 2011 Aug 4.

3.

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development.

Wu J, Matthaei H, Maitra A, Dal Molin M, Wood LD, Eshleman JR, Goggins M, Canto MI, Schulick RD, Edil BH, Wolfgang CL, Klein AP, Diaz LA Jr, Allen PJ, Schmidt CM, Kinzler KW, Papadopoulos N, Hruban RH, Vogelstein B.

Sci Transl Med. 2011 Jul 20;3(92):92ra66. doi: 10.1126/scitranslmed.3002543.

4.

Exploring the genomes of cancer cells: progress and promise.

Stratton MR.

Science. 2011 Mar 25;331(6024):1553-8. doi: 10.1126/science.1204040. Review.

PMID:
21436442
5.

Making sense of cancer genomic data.

Chin L, Hahn WC, Getz G, Meyerson M.

Genes Dev. 2011 Mar 15;25(6):534-55. doi: 10.1101/gad.2017311. Review. Erratum in: Genes Dev. 2012 May 1;26(9):1003.

6.

Cystic precursors to invasive pancreatic cancer.

Matthaei H, Schulick RD, Hruban RH, Maitra A.

Nat Rev Gastroenterol Hepatol. 2011 Mar;8(3):141-50. doi: 10.1038/nrgastro.2011.2. Review.

7.

Cyst fluid interleukin-1beta (IL1beta) levels predict the risk of carcinoma in intraductal papillary mucinous neoplasms of the pancreas.

Maker AV, Katabi N, Qin LX, Klimstra DS, Schattner M, Brennan MF, Jarnagin WR, Allen PJ.

Clin Cancer Res. 2011 Mar 15;17(6):1502-8. doi: 10.1158/1078-0432.CCR-10-1561. Epub 2011 Jan 25.

8.

K-ras mutations correlate with atypical cytology and elevated CEA levels in pancreatic cystic neoplasms.

Mertz H.

Dig Dis Sci. 2011 Jul;56(7):2197-201. doi: 10.1007/s10620-010-1556-z. Epub 2011 Jan 25.

PMID:
21264513
9.

DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors.

Jiao Y, Shi C, Edil BH, de Wilde RF, Klimstra DS, Maitra A, Schulick RD, Tang LH, Wolfgang CL, Choti MA, Velculescu VE, Diaz LA Jr, Vogelstein B, Kinzler KW, Hruban RH, Papadopoulos N.

Science. 2011 Mar 4;331(6021):1199-203. doi: 10.1126/science.1200609. Epub 2011 Jan 20.

10.

Controversies in the management of pancreatic IPMN.

Tanaka M.

Nat Rev Gastroenterol Hepatol. 2011 Jan;8(1):56-60. doi: 10.1038/nrgastro.2010.193. Review.

PMID:
21212775
11.

The genetic landscape of the childhood cancer medulloblastoma.

Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, VandenBerg S, Berger MS, Marie SK, Shinjo SM, Clara C, Phillips PC, Minturn JE, Biegel JA, Judkins AR, Resnick AC, Storm PB, Curran T, He Y, Rasheed BA, Friedman HS, Keir ST, McLendon R, Northcott PA, Taylor MD, Burger PC, Riggins GJ, Karchin R, Parmigiani G, Bigner DD, Yan H, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE.

Science. 2011 Jan 28;331(6016):435-9. doi: 10.1126/science.1198056. Epub 2010 Dec 16.

12.

RNF43 interacts with NEDL1 and regulates p53-mediated transcription.

Shinada K, Tsukiyama T, Sho T, Okumura F, Asaka M, Hatakeyama S.

Biochem Biophys Res Commun. 2011 Jan 7;404(1):143-7. doi: 10.1016/j.bbrc.2010.11.082. Epub 2010 Nov 23.

PMID:
21108931
13.

Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma.

Jones S, Wang TL, Shih IeM, Mao TL, Nakayama K, Roden R, Glas R, Slamon D, Diaz LA Jr, Vogelstein B, Kinzler KW, Velculescu VE, Papadopoulos N.

Science. 2010 Oct 8;330(6001):228-31. doi: 10.1126/science.1196333. Epub 2010 Sep 8.

14.

Hypoxia-inducible factor 1: regulator of mitochondrial metabolism and mediator of ischemic preconditioning.

Semenza GL.

Biochim Biophys Acta. 2011 Jul;1813(7):1263-8. doi: 10.1016/j.bbamcr.2010.08.006. Epub 2010 Aug 21. Review.

15.

High prevalence of pancreatic cysts detected by screening magnetic resonance imaging examinations.

de Jong K, Nio CY, Hermans JJ, Dijkgraaf MG, Gouma DJ, van Eijck CH, van Heel E, Klass G, Fockens P, Bruno MJ.

Clin Gastroenterol Hepatol. 2010 Sep;8(9):806-11. doi: 10.1016/j.cgh.2010.05.017. Epub 2010 Jun 1.

PMID:
20621679
16.

Prevalence of incidental pancreatic cysts in the adult population on MR imaging.

Lee KS, Sekhar A, Rofsky NM, Pedrosa I.

Am J Gastroenterol. 2010 Sep;105(9):2079-84. doi: 10.1038/ajg.2010.122. Epub 2010 Mar 30.

PMID:
20354507
17.

Solid pseudopapillary neoplasms of the pancreas.

Reddy S, Wolfgang CL.

Adv Surg. 2009;43:269-82. Review.

PMID:
19845185
18.

Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations.

Carter H, Chen S, Isik L, Tyekucheva S, Velculescu VE, Kinzler KW, Vogelstein B, Karchin R.

Cancer Res. 2009 Aug 15;69(16):6660-7. doi: 10.1158/0008-5472.CAN-09-1133. Epub 2009 Aug 4.

19.

Regulation of Wnt/beta-catenin signaling by protein kinases.

Verheyen EM, Gottardi CJ.

Dev Dyn. 2010 Jan;239(1):34-44. doi: 10.1002/dvdy.22019. Review.

20.

Rab GTPases as coordinators of vesicle traffic.

Stenmark H.

Nat Rev Mol Cell Biol. 2009 Aug;10(8):513-25. doi: 10.1038/nrm2728. Epub 2009 Jul 15. Review.

PMID:
19603039

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