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Items: 1 to 20 of 95

1.

Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages.

Jiang D, Brady CA, Johnson TM, Lee EY, Park EJ, Scott MP, Attardi LD.

Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17123-8. doi: 10.1073/pnas.1111245108. Epub 2011 Oct 3.

2.

Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression.

Brady CA, Jiang D, Mello SS, Johnson TM, Jarvis LA, Kozak MM, Kenzelmann Broz D, Basak S, Park EJ, McLaughlin ME, Karnezis AN, Attardi LD.

Cell. 2011 May 13;145(4):571-83. doi: 10.1016/j.cell.2011.03.035.

3.

Role of p53 serine 46 in p53 target gene regulation.

Smeenk L, van Heeringen SJ, Koeppel M, Gilbert B, Janssen-Megens E, Stunnenberg HG, Lohrum M.

PLoS One. 2011 Mar 4;6(3):e17574. doi: 10.1371/journal.pone.0017574.

4.

CKI╬▒ ablation highlights a critical role for p53 in invasiveness control.

Elyada E, Pribluda A, Goldstein RE, Morgenstern Y, Brachya G, Cojocaru G, Snir-Alkalay I, Burstain I, Haffner-Krausz R, Jung S, Wiener Z, Alitalo K, Oren M, Pikarsky E, Ben-Neriah Y.

Nature. 2011 Feb 17;470(7334):409-13. doi: 10.1038/nature09673.

PMID:
21331045
5.

Gadd45a functions as a promoter or suppressor of breast cancer dependent on the oncogenic stress.

Tront JS, Huang Y, Fornace AJ Jr, Hoffman B, Liebermann DA.

Cancer Res. 2010 Dec 1;70(23):9671-81. doi: 10.1158/0008-5472.CAN-10-2177. Epub 2010 Nov 23. Erratum in: Cancer Res. 2011 Feb 15;71(4):1506. Fornace, Albert A Jr [corrected to Fornace, Albert J Jr].

6.

p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium.

Cole AM, Ridgway RA, Derkits SE, Parry L, Barker N, Clevers H, Clarke AR, Sansom OJ.

EMBO Mol Med. 2010 Nov;2(11):472-86. doi: 10.1002/emmm.201000101.

7.

Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis.

Beaudry VG, Jiang D, Dusek RL, Park EJ, Knezevich S, Ridd K, Vogel H, Bastian BC, Attardi LD.

PLoS Genet. 2010 Oct 21;6(10):e1001168. doi: 10.1371/journal.pgen.1001168.

8.

p53 at a glance.

Brady CA, Attardi LD.

J Cell Sci. 2010 Aug 1;123(Pt 15):2527-32. doi: 10.1242/jcs.064501. Review. No abstract available.

9.

CD95 promotes tumour growth.

Chen L, Park SM, Tumanov AV, Hau A, Sawada K, Feig C, Turner JR, Fu YX, Romero IL, Lengyel E, Peter ME.

Nature. 2010 May 27;465(7297):492-6. doi: 10.1038/nature09075. Erratum in: Nature. 2011 Jul 14;475(7355):254. Nature. 2011 Mar 10;471(7337):254. Nature. 2012 Nov 29;491(7426):784.

10.

The isoforms of the p53 protein.

Khoury MP, Bourdon JC.

Cold Spring Harb Perspect Biol. 2010 Mar;2(3):a000927. doi: 10.1101/cshperspect.a000927. Review.

11.

Fas/CD95 deficiency in ApcMin/+ mice increases intestinal tumor burden.

Guillen-Ahlers H, Suckow MA, Castellino FJ, Ploplis VA.

PLoS One. 2010 Feb 5;5(2):e9070. doi: 10.1371/journal.pone.0009070.

12.

When mutants gain new powers: news from the mutant p53 field.

Brosh R, Rotter V.

Nat Rev Cancer. 2009 Oct;9(10):701-13. doi: 10.1038/nrc2693. Epub 2009 Aug 20. Review.

PMID:
19693097
13.

Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression.

Hinkal G, Parikh N, Donehower LA.

PLoS One. 2009 Aug 14;4(8):e6654. doi: 10.1371/journal.pone.0006654.

14.

Noxa: at the tip of the balance between life and death.

Ploner C, Kofler R, Villunger A.

Oncogene. 2008 Dec;27 Suppl 1:S84-92. doi: 10.1038/onc.2009.46. Review.

15.

DNA damage- and stress-induced apoptosis occurs independently of PIDD.

Kim IR, Murakami K, Chen NJ, Saibil SD, Matysiak-Zablocki E, Elford AR, Bonnard M, Benchimol S, Jurisicova A, Yeh WC, Ohashi PS.

Apoptosis. 2009 Sep;14(9):1039-49. doi: 10.1007/s10495-009-0375-1.

PMID:
19575295
16.

Blinded by the Light: The Growing Complexity of p53.

Vousden KH, Prives C.

Cell. 2009 May 1;137(3):413-31. doi: 10.1016/j.cell.2009.04.037. Review.

17.

Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2.

Ferreon JC, Lee CW, Arai M, Martinez-Yamout MA, Dyson HJ, Wright PE.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6591-6. doi: 10.1073/pnas.0811023106. Epub 2009 Apr 8.

18.

PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt.

Kawase T, Ohki R, Shibata T, Tsutsumi S, Kamimura N, Inazawa J, Ohta T, Ichikawa H, Aburatani H, Tashiro F, Taya Y.

Cell. 2009 Feb 6;136(3):535-50. doi: 10.1016/j.cell.2008.12.002.

19.

Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis.

Michalak EM, Jansen ES, Happo L, Cragg MS, Tai L, Smyth GK, Strasser A, Adams JM, Scott CL.

Cell Death Differ. 2009 May;16(5):684-96. doi: 10.1038/cdd.2008.195. Epub 2009 Jan 16.

20.

The mitochondrial p53 pathway.

Vaseva AV, Moll UM.

Biochim Biophys Acta. 2009 May;1787(5):414-20. doi: 10.1016/j.bbabio.2008.10.005. Epub 2008 Oct 25. Review.

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