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Items: 1 to 20 of 44

1.

Brain insulin controls adipose tissue lipolysis and lipogenesis.

Scherer T, O'Hare J, Diggs-Andrews K, Schweiger M, Cheng B, Lindtner C, Zielinski E, Vempati P, Su K, Dighe S, Milsom T, Puchowicz M, Scheja L, Zechner R, Fisher SJ, Previs SF, Buettner C.

Cell Metab. 2011 Feb 2;13(2):183-94. doi: 10.1016/j.cmet.2011.01.008.

2.

Obesity and leptin resistance: distinguishing cause from effect.

Myers MG Jr, Leibel RL, Seeley RJ, Schwartz MW.

Trends Endocrinol Metab. 2010 Nov;21(11):643-51. doi: 10.1016/j.tem.2010.08.002. Epub 2010 Sep 16. Review.

3.

Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically.

Stanley S, Pinto S, Segal J, Pérez CA, Viale A, DeFalco J, Cai X, Heisler LK, Friedman JM.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7024-9. doi: 10.1073/pnas.1002790107. Epub 2010 Mar 29.

4.

Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons.

Williams KW, Margatho LO, Lee CE, Choi M, Lee S, Scott MM, Elias CF, Elmquist JK.

J Neurosci. 2010 Feb 17;30(7):2472-9. doi: 10.1523/JNEUROSCI.3118-09.2010.

5.

Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis.

Reed AS, Unger EK, Olofsson LE, Piper ML, Myers MG Jr, Xu AW.

Diabetes. 2010 Apr;59(4):894-906. doi: 10.2337/db09-1024. Epub 2010 Jan 12.

6.

The role of the autonomic nervous liver innervation in the control of energy metabolism.

Yi CX, la Fleur SE, Fliers E, Kalsbeek A.

Biochim Biophys Acta. 2010 Apr;1802(4):416-31. doi: 10.1016/j.bbadis.2010.01.006. Epub 2010 Jan 11. Review.

7.

Leptin targets in the mouse brain.

Scott MM, Lachey JL, Sternson SM, Lee CE, Elias CF, Friedman JM, Elmquist JK.

J Comp Neurol. 2009 Jun 10;514(5):518-32. doi: 10.1002/cne.22025.

8.

Leptin regulates peripheral lipid metabolism primarily through central effects on food intake.

Prieur X, Tung YC, Griffin JL, Farooqi IS, O'Rahilly S, Coll AP.

Endocrinology. 2008 Nov;149(11):5432-9. doi: 10.1210/en.2008-0498. Epub 2008 Jul 17.

9.

Leptin controls adipose tissue lipogenesis via central, STAT3-independent mechanisms.

Buettner C, Muse ED, Cheng A, Chen L, Scherer T, Pocai A, Su K, Cheng B, Li X, Harvey-White J, Schwartz GJ, Kunos G, Rossetti L, Buettner C.

Nat Med. 2008 Jun;14(6):667-75. doi: 10.1038/nm1775. Epub 2008 Jun 1.

10.

Central insulin action regulates peripheral glucose and fat metabolism in mice.

Koch L, Wunderlich FT, Seibler J, Könner AC, Hampel B, Irlenbusch S, Brabant G, Kahn CR, Schwenk F, Brüning JC.

J Clin Invest. 2008 Jun;118(6):2132-47. doi: 10.1172/JCI31073.

11.
12.

Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis.

Biddinger SB, Hernandez-Ono A, Rask-Madsen C, Haas JT, Alemán JO, Suzuki R, Scapa EF, Agarwal C, Carey MC, Stephanopoulos G, Cohen DE, King GL, Ginsberg HN, Kahn CR.

Cell Metab. 2008 Feb;7(2):125-34. doi: 10.1016/j.cmet.2007.11.013.

13.

Selective versus total insulin resistance: a pathogenic paradox.

Brown MS, Goldstein JL.

Cell Metab. 2008 Feb;7(2):95-6. doi: 10.1016/j.cmet.2007.12.009. Review.

14.

Specific physiological roles for signal transducer and activator of transcription 3 in leptin receptor-expressing neurons.

Piper ML, Unger EK, Myers MG Jr, Xu AW.

Mol Endocrinol. 2008 Mar;22(3):751-9. Epub 2007 Dec 20.

15.
16.

Mechanisms of leptin action and leptin resistance.

Myers MG, Cowley MA, Münzberg H.

Annu Rev Physiol. 2008;70:537-56. Review.

PMID:
17937601
17.

Tissue-specific effects of central leptin on the expression of genes involved in lipid metabolism in liver and white adipose tissue.

Gallardo N, Bonzón-Kulichenko E, Fernández-Agulló T, Moltó E, Gómez-Alonso S, Blanco P, Carrascosa JM, Ros M, Andrés A.

Endocrinology. 2007 Dec;148(12):5604-10. Epub 2007 Sep 6.

PMID:
17823267
18.

Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.

Monetti M, Levin MC, Watt MJ, Sajan MP, Marmor S, Hubbard BK, Stevens RD, Bain JR, Newgard CB, Farese RV Sr, Hevener AL, Farese RV Jr.

Cell Metab. 2007 Jul;6(1):69-78.

19.

Disruption of peripheral leptin signaling in mice results in hyperleptinemia without associated metabolic abnormalities.

Guo K, McMinn JE, Ludwig T, Yu YH, Yang G, Chen L, Loh D, Li C, Chua S Jr, Zhang Y.

Endocrinology. 2007 Aug;148(8):3987-97. Epub 2007 May 10.

PMID:
17495001
20.

Leptin receptor signaling and action in the central nervous system.

Leshan RL, Björnholm M, Münzberg H, Myers MG Jr.

Obesity (Silver Spring). 2006 Aug;14 Suppl 5:208S-212S. Review.

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