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Items: 1 to 20 of 58

1.

New insights into the role of PPARs.

Montagner A, Rando G, Degueurce G, Leuenberger N, Michalik L, Wahli W.

Prostaglandins Leukot Essent Fatty Acids. 2011 Nov;85(5):235-43. doi: 10.1016/j.plefa.2011.04.016. Epub 2011 Jul 20. Review.

PMID:
21778043
2.

Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity.

Zechner C, Lai L, Zechner JF, Geng T, Yan Z, Rumsey JW, Collia D, Chen Z, Wozniak DF, Leone TC, Kelly DP.

Cell Metab. 2010 Dec 1;12(6):633-42. doi: 10.1016/j.cmet.2010.11.008. Erratum in: Cell Metab. 2011 Jan 5;13(1):114.

3.

Endogenous ligands for nuclear receptors: digging deeper.

Schupp M, Lazar MA.

J Biol Chem. 2010 Dec 24;285(52):40409-15. doi: 10.1074/jbc.R110.182451. Epub 2010 Oct 18. Review.

4.

Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation.

Bungard D, Fuerth BJ, Zeng PY, Faubert B, Maas NL, Viollet B, Carling D, Thompson CB, Jones RG, Berger SL.

Science. 2010 Sep 3;329(5996):1201-5. doi: 10.1126/science.1191241. Epub 2010 Jul 15.

5.
6.

PPAR{delta} agonism activates fatty acid oxidation via PGC-1{alpha} but does not increase mitochondrial gene expression and function.

Kleiner S, Nguyen-Tran V, Baré O, Huang X, Spiegelman B, Wu Z.

J Biol Chem. 2009 Jul 10;284(28):18624-33. doi: 10.1074/jbc.M109.008797. Epub 2009 May 12.

7.

AMP-activated protein kinase in skeletal muscle: from structure and localization to its role as a master regulator of cellular metabolism.

Witczak CA, Sharoff CG, Goodyear LJ.

Cell Mol Life Sci. 2008 Nov;65(23):3737-55. doi: 10.1007/s00018-008-8244-6. Review.

PMID:
18810325
8.

AMPK and PPARdelta agonists are exercise mimetics.

Narkar VA, Downes M, Yu RT, Embler E, Wang YX, Banayo E, Mihaylova MM, Nelson MC, Zou Y, Juguilon H, Kang H, Shaw RJ, Evans RM.

Cell. 2008 Aug 8;134(3):405-15. doi: 10.1016/j.cell.2008.06.051. Epub 2008 Jul 31.

9.

The PPAR trio: regulators of myocardial energy metabolism in health and disease.

Madrazo JA, Kelly DP.

J Mol Cell Cardiol. 2008 Jun;44(6):968-75. doi: 10.1016/j.yjmcc.2008.03.021. Epub 2008 Apr 4. Review.

PMID:
18462747
10.

Muscle-specific expression of PPARgamma coactivator-1alpha improves exercise performance and increases peak oxygen uptake.

Calvo JA, Daniels TG, Wang X, Paul A, Lin J, Spiegelman BM, Stevenson SC, Rangwala SM.

J Appl Physiol (1985). 2008 May;104(5):1304-12. doi: 10.1152/japplphysiol.01231.2007. Epub 2008 Jan 31.

PMID:
18239076
11.

AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5.

McGee SL, van Denderen BJ, Howlett KF, Mollica J, Schertzer JD, Kemp BE, Hargreaves M.

Diabetes. 2008 Apr;57(4):860-7. doi: 10.2337/db07-0843. Epub 2008 Jan 9.

12.

Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart.

Burkart EM, Sambandam N, Han X, Gross RW, Courtois M, Gierasch CM, Shoghi K, Welch MJ, Kelly DP.

J Clin Invest. 2007 Dec;117(12):3930-9.

13.

A role for the transcriptional coactivator PGC-1alpha in muscle refueling.

Wende AR, Schaeffer PJ, Parker GJ, Zechner C, Han DH, Chen MM, Hancock CR, Lehman JJ, Huss JM, McClain DA, Holloszy JO, Kelly DP.

J Biol Chem. 2007 Dec 14;282(50):36642-51. Epub 2007 Oct 11.

14.
15.

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

Woods A, Dickerson K, Heath R, Hong SP, Momcilovic M, Johnstone SR, Carlson M, Carling D.

Cell Metab. 2005 Jul;2(1):21-33.

16.

Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase.

Hawley SA, Pan DA, Mustard KJ, Ross L, Bain J, Edelman AM, Frenguelli BG, Hardie DG.

Cell Metab. 2005 Jul;2(1):9-19.

17.

A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes.

Finck BN, Bernal-Mizrachi C, Han DH, Coleman T, Sambandam N, LaRiviere LL, Holloszy JO, Semenkovich CF, Kelly DP.

Cell Metab. 2005 Feb;1(2):133-44.

18.

Exercise-induced increase in muscle insulin sensitivity.

Holloszy JO.

J Appl Physiol (1985). 2005 Jul;99(1):338-43. Review.

PMID:
16036907
19.

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.

Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, Abel ED, Semenkovich CF, Kelly DP.

PLoS Biol. 2005 Apr;3(4):e101. Epub 2005 Mar 15.

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