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Items: 1 to 20 of 59

1.

A switching mechanism in doxorubicin bioactivation can be exploited to control doxorubicin toxicity.

Finn NA, Findley HW, Kemp ML.

PLoS Comput Biol. 2011 Sep;7(9):e1002151. doi: 10.1371/journal.pcbi.1002151. Epub 2011 Sep 15.

2.

Cancer: when antioxidants are bad.

Perera RM, Bardeesy N.

Nature. 2011 Jul 6;475(7354):43-4. doi: 10.1038/475043a. No abstract available.

PMID:
21734699
3.

Glutathione synthesis and turnover in the human erythrocyte: alignment of a model based on detailed enzyme kinetics with experimental data.

Raftos JE, Whillier S, Kuchel PW.

J Biol Chem. 2010 Jul 30;285(31):23557-67. doi: 10.1074/jbc.M109.067017. Epub 2010 May 24.

4.

A model of redox kinetics implicates the thiol proteome in cellular hydrogen peroxide responses.

Adimora NJ, Jones DP, Kemp ML.

Antioxid Redox Signal. 2010 Sep 15;13(6):731-43. doi: 10.1089/ars.2009.2968.

5.

Addressing reported pro-apoptotic functions of NF-kappaB: targeted inhibition of canonical NF-kappaB enhances the apoptotic effects of doxorubicin.

Bednarski BK, Baldwin AS Jr, Kim HJ.

PLoS One. 2009 Sep 10;4(9):e6992. doi: 10.1371/journal.pone.0006992.

6.

Role of hydrogen peroxide in NF-kappaB activation: from inducer to modulator.

Oliveira-Marques V, Marinho HS, Cyrne L, Antunes F.

Antioxid Redox Signal. 2009 Sep;11(9):2223-43. doi: 10.1089/ARS.2009.2601. Review.

PMID:
19496701
7.

Covalent cross-linking of glutathione and carnosine to proteins by 4-oxo-2-nonenal.

Zhu X, Gallogly MM, Mieyal JJ, Anderson VE, Sayre LM.

Chem Res Toxicol. 2009 Jun;22(6):1050-9. doi: 10.1021/tx9000144.

8.

N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes.

Shi R, Huang CC, Aronstam RS, Ercal N, Martin A, Huang YW.

BMC Pharmacol. 2009 Apr 15;9:7. doi: 10.1186/1471-2210-9-7.

9.

Protein S-glutathionylation: a regulatory device from bacteria to humans.

Dalle-Donne I, Rossi R, Colombo G, Giustarini D, Milzani A.

Trends Biochem Sci. 2009 Feb;34(2):85-96. doi: 10.1016/j.tibs.2008.11.002. Epub 2009 Jan 8. Review.

PMID:
19135374
10.

Glutaredoxin regulates autocrine and paracrine proinflammatory responses in retinal glial (muller) cells.

Shelton MD, Distler AM, Kern TS, Mieyal JJ.

J Biol Chem. 2009 Feb 20;284(8):4760-6. doi: 10.1074/jbc.M805464200. Epub 2008 Dec 12.

11.

Glutathionylation regulates IkappaB.

Kil IS, Kim SY, Park JW.

Biochem Biophys Res Commun. 2008 Aug 15;373(1):169-73. doi: 10.1016/j.bbrc.2008.06.007. Epub 2008 Jun 13.

PMID:
18555796
12.

Thiol chemistry and specificity in redox signaling.

Winterbourn CC, Hampton MB.

Free Radic Biol Med. 2008 Sep 1;45(5):549-61. doi: 10.1016/j.freeradbiomed.2008.05.004. Epub 2008 May 16. Review.

PMID:
18544350
13.

Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347.

Herscovitch M, Comb W, Ennis T, Coleman K, Yong S, Armstead B, Kalaitzidis D, Chandani S, Gilmore TD.

Biochem Biophys Res Commun. 2008 Feb 29;367(1):103-8. doi: 10.1016/j.bbrc.2007.12.123. Epub 2007 Dec 28.

14.

ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis.

D'Autréaux B, Toledano MB.

Nat Rev Mol Cell Biol. 2007 Oct;8(10):813-24. Review.

PMID:
17848967
15.

An introduction to the metabolic determinants of anthracycline cardiotoxicity.

Menna P, Recalcati S, Cairo G, Minotti G.

Cardiovasc Toxicol. 2007;7(2):80-5. Review.

PMID:
17652809
16.
17.

Glutathione supplementation potentiates hypoxic apoptosis by S-glutathionylation of p65-NFkappaB.

Qanungo S, Starke DW, Pai HV, Mieyal JJ, Nieminen AL.

J Biol Chem. 2007 Jun 22;282(25):18427-36. Epub 2007 Apr 27.

18.

A quantitative study of NF-kappaB activation by H2O2: relevance in inflammation and synergy with TNF-alpha.

de Oliveira-Marques V, Cyrne L, Marinho HS, Antunes F.

J Immunol. 2007 Mar 15;178(6):3893-902. Erratum in: J Immunol. 2007 May 15;178(10):6654.

19.

Dimerization of the I kappa B kinase-binding domain of NEMO is required for tumor necrosis factor alpha-induced NF-kappa B activity.

Marienfeld RB, Palkowitsch L, Ghosh S.

Mol Cell Biol. 2006 Dec;26(24):9209-19. Epub 2006 Sep 25.

20.

Free radicals and antioxidants in normal physiological functions and human disease.

Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J.

Int J Biochem Cell Biol. 2007;39(1):44-84. Epub 2006 Aug 4. Review.

PMID:
16978905

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