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Transcriptional regulation of BMP2 expression by the PTH-CREB signaling pathway in osteoblasts.

Zhang R, Edwards JR, Ko SY, Dong S, Liu H, Oyajobi BO, Papasian C, Deng HW, Zhao M.

PLoS One. 2011;6(6):e20780. doi: 10.1371/journal.pone.0020780.


CREB is a regulatory target for the protein kinase Akt/PKB in the differentiation of pancreatic ductal cells into islet β-cells mediated by hepatocyte growth factor.

Li XY, Zhan XR, Liu XM, Wang XC.

Biochem Biophys Res Commun. 2011 Jan 14;404(2):711-6. doi: 10.1016/j.bbrc.2010.12.048.


Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition.

Fulzele K, Riddle RC, DiGirolamo DJ, Cao X, Wan C, Chen D, Faugere MC, Aja S, Hussain MA, Brüning JC, Clemens TL.

Cell. 2010 Jul 23;142(2):309-19. doi: 10.1016/j.cell.2010.06.002.


Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism.

Ferron M, Wei J, Yoshizawa T, Del Fattore A, DePinho RA, Teti A, Ducy P, Karsenty G.

Cell. 2010 Jul 23;142(2):296-308. doi: 10.1016/j.cell.2010.06.003.


The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice.

Greenblatt MB, Shim JH, Zou W, Sitara D, Schweitzer M, Hu D, Lotinun S, Sano Y, Baron R, Park JM, Arthur S, Xie M, Schneider MD, Zhai B, Gygi S, Davis R, Glimcher LH.

J Clin Invest. 2010 Jul;120(7):2457-73. doi: 10.1172/JCI42285.


CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain.

Wang J, Weaver IC, Gauthier-Fisher A, Wang H, He L, Yeomans J, Wondisford F, Kaplan DR, Miller FD.

Dev Cell. 2010 Jan 19;18(1):114-25. doi: 10.1016/j.devcel.2009.10.023.


The nuts and bolts of AGC protein kinases.

Pearce LR, Komander D, Alessi DR.

Nat Rev Mol Cell Biol. 2010 Jan;11(1):9-22. doi: 10.1038/nrm2822. Review.


Two patients with EP300 mutations and facial dysmorphism different from the classic Rubinstein-Taybi syndrome.

Bartsch O, Labonté J, Albrecht B, Wieczorek D, Lechno S, Zechner U, Haaf T.

Am J Med Genet A. 2010 Jan;152A(1):181-4. doi: 10.1002/ajmg.a.33153.


Selective signaling by Akt2 promotes bone morphogenetic protein 2-mediated osteoblast differentiation.

Mukherjee A, Wilson EM, Rotwein P.

Mol Cell Biol. 2010 Feb;30(4):1018-27. doi: 10.1128/MCB.01401-09.


Akt promotes BMP2-mediated osteoblast differentiation and bone development.

Mukherjee A, Rotwein P.

J Cell Sci. 2009 Mar 1;122(Pt 5):716-26. doi: 10.1242/jcs.042770.


Endochondral ossification is required for haematopoietic stem-cell niche formation.

Chan CK, Chen CC, Luppen CA, Kim JB, DeBoer AT, Wei K, Helms JA, Kuo CJ, Kraft DL, Weissman IL.

Nature. 2009 Jan 22;457(7228):490-4. doi: 10.1038/nature07547.


Insulin-like growth factor-I and bone: lessons from mice and men.

Kawai M, Rosen CJ.

Pediatr Nephrol. 2009 Jul;24(7):1277-85. doi: 10.1007/s00467-008-1040-6. Review.


Akt1 in osteoblasts and osteoclasts controls bone remodeling.

Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Chen WS, Hay N, Tobe K, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, Kawaguchi H.

PLoS One. 2007 Oct 24;2(10):e1058.


Oro-dental features as useful diagnostic tool in Rubinstein-Taybi syndrome.

Bloch-Zupan A, Stachtou J, Emmanouil D, Arveiler B, Griffiths D, Lacombe D.

Am J Med Genet A. 2007 Mar 15;143A(6):570-3.


Differential activation of CREB by Akt1 and Akt2.

Kato S, Ding J, Du K.

Biochem Biophys Res Commun. 2007 Mar 23;354(4):1061-6.


BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing.

Tsuji K, Bandyopadhyay A, Harfe BD, Cox K, Kakar S, Gerstenfeld L, Einhorn T, Tabin CJ, Rosen V.

Nat Genet. 2006 Dec;38(12):1424-9.


Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3.

Jones DC, Wein MN, Oukka M, Hofstaetter JG, Glimcher MJ, Glimcher LH.

Science. 2006 May 26;312(5777):1223-7.


Role of hepatic STAT3 in brain-insulin action on hepatic glucose production.

Inoue H, Ogawa W, Asakawa A, Okamoto Y, Nishizawa A, Matsumoto M, Teshigawara K, Matsuki Y, Watanabe E, Hiramatsu R, Notohara K, Katayose K, Okamura H, Kahn CR, Noda T, Takeda K, Akira S, Inui A, Kasuga M.

Cell Metab. 2006 Apr;3(4):267-75.


Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture.

Barco A, Patterson SL, Alarcon JM, Gromova P, Mata-Roig M, Morozov A, Kandel ER.

Neuron. 2005 Oct 6;48(1):123-37. Erratum in: Neuron. 2007 Dec 6;56(5):936. Neuron. 2011 Mar 10;69(5):1037. Patterson, Susan [corrected to Patterson, Susan L].

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