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Items: 1 to 20 of 38


Lipid-binding surfaces of membrane proteins: evidence from evolutionary and structural analysis.

Adamian L, Naveed H, Liang J.

Biochim Biophys Acta. 2011 Apr;1808(4):1092-102. doi: 10.1016/j.bbamem.2010.12.008. Epub 2010 Dec 16.


Oligomerization of the mitochondrial protein voltage-dependent anion channel is coupled to the induction of apoptosis.

Keinan N, Tyomkin D, Shoshan-Barmatz V.

Mol Cell Biol. 2010 Dec;30(24):5698-709. doi: 10.1128/MCB.00165-10. Epub 2010 Oct 11.


VDAC, a multi-functional mitochondrial protein regulating cell life and death.

Shoshan-Barmatz V, De Pinto V, Zweckstetter M, Raviv Z, Keinan N, Arbel N.

Mol Aspects Med. 2010 Jun;31(3):227-85. doi: 10.1016/j.mam.2010.03.002. Epub 2010 Mar 23. Review.


Apoptosis is regulated by the VDAC1 N-terminal region and by VDAC oligomerization: release of cytochrome c, AIF and Smac/Diablo.

Shoshan-Barmatz V, Keinan N, Abu-Hamad S, Tyomkin D, Aram L.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1281-91. doi: 10.1016/j.bbabio.2010.03.003. Epub 2010 Mar 6.


VDAC1 cysteine residues: topology and function in channel activity and apoptosis.

Aram L, Geula S, Arbel N, Shoshan-Barmatz V.

Biochem J. 2010 Apr 14;427(3):445-54. doi: 10.1042/BJ20091690. Erratum in: Biochem J. 2010 Jul 14;429(3):613-4.


Structure-function relationships in feedback regulation of energy fluxes in vivo in health and disease: mitochondrial interactosome.

Saks V, Guzun R, Timohhina N, Tepp K, Varikmaa M, Monge C, Beraud N, Kaambre T, Kuznetsov A, Kadaja L, Eimre M, Seppet E.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):678-97. doi: 10.1016/j.bbabio.2010.01.011. Epub 2010 Jan 21. Review.


The mitochondrial porin, VDAC, has retained the ability to be assembled in the bacterial outer membrane.

Walther DM, Bos MP, Rapaport D, Tommassen J.

Mol Biol Evol. 2010 Apr;27(4):887-95. doi: 10.1093/molbev/msp294. Epub 2009 Dec 3.


The published 3D structure of the VDAC channel: native or not?

Colombini M.

Trends Biochem Sci. 2009 Aug;34(8):382-9. doi: 10.1016/j.tibs.2009.05.001. Epub 2009 Jul 31.


Predicting weakly stable regions, oligomerization state, and protein-protein interfaces in transmembrane domains of outer membrane proteins.

Naveed H, Jackups R Jr, Liang J.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12735-40. doi: 10.1073/pnas.0902169106. Epub 2009 Jul 21.


Crystal packing analysis of murine VDAC1 crystals in a lipidic environment reveals novel insights on oligomerization and orientation.

Ujwal R, Cascio D, Chaptal V, Ping P, Abramson J.

Channels (Austin). 2009 May-Jun;3(3):167-70. Epub 2009 May 15.


The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins.

Abu-Hamad S, Arbel N, Calo D, Arzoine L, Israelson A, Keinan N, Ben-Romano R, Friedman O, Shoshan-Barmatz V.

J Cell Sci. 2009 Jun 1;122(Pt 11):1906-16. doi: 10.1242/jcs.040188.


Signals in bacterial beta-barrel proteins are functional in eukaryotic cells for targeting to and assembly in mitochondria.

Walther DM, Papic D, Bos MP, Tommassen J, Rapaport D.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2531-6. doi: 10.1073/pnas.0807830106. Epub 2009 Jan 30.


Key regions of VDAC1 functioning in apoptosis induction and regulation by hexokinase.

Shoshan-Barmatz V, Zakar M, Rosenthal K, Abu-Hamad S.

Biochim Biophys Acta. 2009 May;1787(5):421-30. doi: 10.1016/j.bbabio.2008.11.009. Epub 2008 Nov 27.


The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating.

Ujwal R, Cascio D, Colletier JP, Faham S, Zhang J, Toro L, Ping P, Abramson J.

Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17742-7. doi: 10.1073/pnas.0809634105. Epub 2008 Nov 6.


Structure of the human voltage-dependent anion channel.

Bayrhuber M, Meins T, Habeck M, Becker S, Giller K, Villinger S, Vonrhein C, Griesinger C, Zweckstetter M, Zeth K.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15370-5. doi: 10.1073/pnas.0808115105. Epub 2008 Oct 1.


Solution structure of the integral human membrane protein VDAC-1 in detergent micelles.

Hiller S, Garces RG, Malia TJ, Orekhov VY, Colombini M, Wagner G.

Science. 2008 Aug 29;321(5893):1206-10. doi: 10.1126/science.1161302.


The supramolecular assemblies of voltage-dependent anion channels in the native membrane.

Hoogenboom BW, Suda K, Engel A, Fotiadis D.

J Mol Biol. 2007 Jul 6;370(2):246-55. Epub 2007 May 10.


Supramolecular assembly of VDAC in native mitochondrial outer membranes.

Gon├žalves RP, Buzhynskyy N, Prima V, Sturgis JN, Scheuring S.

J Mol Biol. 2007 Jun 1;369(2):413-8. Epub 2007 Mar 30.

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