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Items: 1 to 20 of 29

1.

Biochemical characterization of a multidomain deubiquitinating enzyme Ubp15 and the regulatory role of its terminal domains.

Bozza WP, Zhuang Z.

Biochemistry. 2011 Jul 26;50(29):6423-32. doi: 10.1021/bi200529z. Epub 2011 Jun 28.

PMID:
21710968
2.

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21.

Ye Y, Akutsu M, Reyes-Turcu F, Enchev RI, Wilkinson KD, Komander D.

EMBO Rep. 2011 Apr;12(4):350-7. doi: 10.1038/embor.2011.17. Epub 2011 Mar 11.

3.

C-terminal region of USP7/HAUSP is critical for deubiquitination activity and contains a second mdm2/p53 binding site.

Ma J, Martin JD, Xue Y, Lor LA, Kennedy-Wilson KM, Sinnamon RH, Ho TF, Zhang G, Schwartz B, Tummino PJ, Lai Z.

Arch Biochem Biophys. 2010 Nov 15;503(2):207-12. doi: 10.1016/j.abb.2010.08.020. Epub 2010 Sep 15.

PMID:
20816748
4.

Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin.

Rodrigo-Brenni MC, Foster SA, Morgan DO.

Mol Cell. 2010 Aug 27;39(4):548-59. doi: 10.1016/j.molcel.2010.07.027.

5.

Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne.

Bremm A, Freund SM, Komander D.

Nat Struct Mol Biol. 2010 Aug;17(8):939-47. doi: 10.1038/nsmb.1873. Epub 2010 Jul 11.

6.

Building ubiquitin chains: E2 enzymes at work.

Ye Y, Rape M.

Nat Rev Mol Cell Biol. 2009 Nov;10(11):755-64. doi: 10.1038/nrm2780. Review.

7.

Dissection of USP catalytic domains reveals five common insertion points.

Ye Y, Scheel H, Hofmann K, Komander D.

Mol Biosyst. 2009 Dec;5(12):1797-808. doi: 10.1039/b907669g. Epub 2009 Jul 17.

PMID:
19734957
8.

Breaking the chains: structure and function of the deubiquitinases.

Komander D, Clague MJ, Urbé S.

Nat Rev Mol Cell Biol. 2009 Aug;10(8):550-63. doi: 10.1038/nrm2731. Review.

PMID:
19626045
9.

Defining the human deubiquitinating enzyme interaction landscape.

Sowa ME, Bennett EJ, Gygi SP, Harper JW.

Cell. 2009 Jul 23;138(2):389-403. doi: 10.1016/j.cell.2009.04.042. Epub 2009 Jul 16.

10.

RING domain E3 ubiquitin ligases.

Deshaies RJ, Joazeiro CA.

Annu Rev Biochem. 2009;78:399-434. doi: 10.1146/annurev.biochem.78.101807.093809. Review.

PMID:
19489725
11.

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains.

Komander D, Reyes-Turcu F, Licchesi JD, Odenwaelder P, Wilkinson KD, Barford D.

EMBO Rep. 2009 May;10(5):466-73. doi: 10.1038/embor.2009.55. Epub 2009 Apr 17.

12.

Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism.

Matyskiela ME, Morgan DO.

Mol Cell. 2009 Apr 10;34(1):68-80. doi: 10.1016/j.molcel.2009.02.027.

13.

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation.

Xu P, Duong DM, Seyfried NT, Cheng D, Xie Y, Robert J, Rush J, Hochstrasser M, Finley D, Peng J.

Cell. 2009 Apr 3;137(1):133-45. doi: 10.1016/j.cell.2009.01.041.

14.

Protein partners of deubiquitinating enzymes.

Ventii KH, Wilkinson KD.

Biochem J. 2008 Sep 1;414(2):161-75. doi: 10.1042/BJ20080798. Review.

15.

The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module.

Komander D, Lord CJ, Scheel H, Swift S, Hofmann K, Ashworth A, Barford D.

Mol Cell. 2008 Feb 29;29(4):451-64. doi: 10.1016/j.molcel.2007.12.018.

16.

Mechanisms, biology and inhibitors of deubiquitinating enzymes.

Love KR, Catic A, Schlieker C, Ploegh HL.

Nat Chem Biol. 2007 Nov;3(11):697-705. Review.

PMID:
17948018
17.

Sequential E2s drive polyubiquitin chain assembly on APC targets.

Rodrigo-Brenni MC, Morgan DO.

Cell. 2007 Jul 13;130(1):127-39.

18.

Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH.

Eddins MJ, Varadan R, Fushman D, Pickart CM, Wolberger C.

J Mol Biol. 2007 Mar 16;367(1):204-11. Epub 2006 Dec 29.

PMID:
17240395
19.

Enzymology of the anaphase-promoting complex.

Carroll CW, Morgan DO.

Methods Enzymol. 2005;398:219-30.

PMID:
16275331
20.

Proteasomes and their kin: proteases in the machine age.

Pickart CM, Cohen RE.

Nat Rev Mol Cell Biol. 2004 Mar;5(3):177-87. Review. No abstract available.

PMID:
14990998

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