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Items: 1 to 20 of 31

1.

Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome.

Liu GH, Barkho BZ, Ruiz S, Diep D, Qu J, Yang SL, Panopoulos AD, Suzuki K, Kurian L, Walsh C, Thompson J, Boue S, Fung HL, Sancho-Martinez I, Zhang K, Yates J 3rd, Izpisua Belmonte JC.

Nature. 2011 Apr 14;472(7342):221-5. doi: 10.1038/nature09879.

2.

Cellular senescence: putting the paradoxes in perspective.

Campisi J.

Curr Opin Genet Dev. 2011 Feb;21(1):107-12. doi: 10.1016/j.gde.2010.10.005. Review.

3.

Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues.

Hanna JH, Saha K, Jaenisch R.

Cell. 2010 Nov 12;143(4):508-25. doi: 10.1016/j.cell.2010.10.008. Review.

4.

Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells.

Guenther MG, Frampton GM, Soldner F, Hockemeyer D, Mitalipova M, Jaenisch R, Young RA.

Cell Stem Cell. 2010 Aug 6;7(2):249-57. doi: 10.1016/j.stem.2010.06.015.

5.

Linking functional decline of telomeres, mitochondria and stem cells during ageing.

Sahin E, Depinho RA.

Nature. 2010 Mar 25;464(7288):520-8. doi: 10.1038/nature08982. Review.

6.

Spontaneous reversal of the developmental aging of normal human cells following transcriptional reprogramming.

Vaziri H, Chapman KB, Guigova A, Teichroeb J, Lacher MD, Sternberg H, Singec I, Briggs L, Wheeler J, Sampathkumar J, Gonzalez R, Larocca D, Murai J, Snyder E, Andrews WH, Funk WD, West MD.

Regen Med. 2010 May;5(3):345-63. doi: 10.2217/rme.10.21.

PMID:
20230312
7.

The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells.

Prigione A, Fauler B, Lurz R, Lehrach H, Adjaye J.

Stem Cells. 2010 Apr;28(4):721-33. doi: 10.1002/stem.404.

8.

Hemangioblastic derivatives from human induced pluripotent stem cells exhibit limited expansion and early senescence.

Feng Q, Lu SJ, Klimanskaya I, Gomes I, Kim D, Chung Y, Honig GR, Kim KS, Lanza R.

Stem Cells. 2010 Apr;28(4):704-12. doi: 10.1002/stem.321.

9.

Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells.

Armstrong L, Tilgner K, Saretzki G, Atkinson SP, Stojkovic M, Moreno R, Przyborski S, Lako M.

Stem Cells. 2010 Apr;28(4):661-73. doi: 10.1002/stem.307.

10.

Telomere dynamics in human cells reprogrammed to pluripotency.

Suhr ST, Chang EA, Rodriguez RM, Wang K, Ross PJ, Beyhan Z, Murthy S, Cibelli JB.

PLoS One. 2009 Dec 2;4(12):e8124. doi: 10.1371/journal.pone.0008124. Erratum in: PLoS One. 2010;5(3) doi: 10.1371/annotation/c786d141-fd0f-45fd-80ec-96d80be620dc.

11.

Direct cell reprogramming is a stochastic process amenable to acceleration.

Hanna J, Saha K, Pando B, van Zon J, Lengner CJ, Creyghton MP, van Oudenaarden A, Jaenisch R.

Nature. 2009 Dec 3;462(7273):595-601. doi: 10.1038/nature08592.

12.

Senescence impairs successful reprogramming to pluripotent stem cells.

Banito A, Rashid ST, Acosta JC, Li S, Pereira CF, Geti I, Pinho S, Silva JC, Azuara V, Walsh M, Vallier L, Gil J.

Genes Dev. 2009 Sep 15;23(18):2134-9. doi: 10.1101/gad.1811609.

13.

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells.

Utikal J, Polo JM, Stadtfeld M, Maherali N, Kulalert W, Walsh RM, Khalil A, Rheinwald JG, Hochedlinger K.

Nature. 2009 Aug 27;460(7259):1145-8. doi: 10.1038/nature08285.

14.

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity.

Marión RM, Strati K, Li H, Murga M, Blanco R, Ortega S, Fernandez-Capetillo O, Serrano M, Blasco MA.

Nature. 2009 Aug 27;460(7259):1149-53. doi: 10.1038/nature08287.

15.

The Ink4/Arf locus is a barrier for iPS cell reprogramming.

Li H, Collado M, Villasante A, Strati K, Ortega S, Cañamero M, Blasco MA, Serrano M.

Nature. 2009 Aug 27;460(7259):1136-9. doi: 10.1038/nature08290.

16.

Linking the p53 tumour suppressor pathway to somatic cell reprogramming.

Kawamura T, Suzuki J, Wang YV, Menendez S, Morera LB, Raya A, Wahl GM, Izpisúa Belmonte JC.

Nature. 2009 Aug 27;460(7259):1140-4. doi: 10.1038/nature08311.

17.

Mitochondrial dysfunction contributes to oncogene-induced senescence.

Moiseeva O, Bourdeau V, Roux A, Deschênes-Simard X, Ferbeyre G.

Mol Cell Biol. 2009 Aug;29(16):4495-507. doi: 10.1128/MCB.01868-08.

18.

Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells.

Feng B, Ng JH, Heng JC, Ng HH.

Cell Stem Cell. 2009 Apr 3;4(4):301-12. doi: 10.1016/j.stem.2009.03.005. Review.

19.

Human induced pluripotent stem cells free of vector and transgene sequences.

Yu J, Hu K, Smuga-Otto K, Tian S, Stewart R, Slukvin II, Thomson JA.

Science. 2009 May 8;324(5928):797-801. doi: 10.1126/science.1172482.

20.

Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells.

Marion RM, Strati K, Li H, Tejera A, Schoeftner S, Ortega S, Serrano M, Blasco MA.

Cell Stem Cell. 2009 Feb 6;4(2):141-54. doi: 10.1016/j.stem.2008.12.010.

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