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Items: 1 to 20 of 53

1.

Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance.

Lee HY, Choi CS, Birkenfeld AL, Alves TC, Jornayvaz FR, Jurczak MJ, Zhang D, Woo DK, Shadel GS, Ladiges W, Rabinovitch PS, Santos JH, Petersen KF, Samuel VT, Shulman GI.

Cell Metab. 2010 Dec 1;12(6):668-74. doi: 10.1016/j.cmet.2010.11.004.

2.

Genetic insights into OXPHOS defect and its role in cancer.

Chandra D, Singh KK.

Biochim Biophys Acta. 2011 Jun;1807(6):620-5. doi: 10.1016/j.bbabio.2010.10.023. Epub 2010 Nov 11. Review.

3.

Somatic mutations of mitochondrial DNA in aging and cancer progression.

Lee HC, Chang CM, Chi CW.

Ageing Res Rev. 2010 Nov;9 Suppl 1:S47-58. doi: 10.1016/j.arr.2010.08.009. Epub 2010 Sep 8. Review.

PMID:
20816876
4.

The mitochondrial transcription factor A functions in mitochondrial base excision repair.

Canugovi C, Maynard S, Bayne AC, Sykora P, Tian J, de Souza-Pinto NC, Croteau DL, Bohr VA.

DNA Repair (Amst). 2010 Oct 5;9(10):1080-9. doi: 10.1016/j.dnarep.2010.07.009. Epub 2010 Aug 23.

5.

Core human mitochondrial transcription apparatus is a regulated two-component system in vitro.

Shutt TE, Lodeiro MF, Cotney J, Cameron CE, Shadel GS.

Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12133-8. doi: 10.1073/pnas.0910581107. Epub 2010 Jun 18.

6.

A compendium of human mitochondrial gene expression machinery with links to disease.

Shutt TE, Shadel GS.

Environ Mol Mutagen. 2010 Jun;51(5):360-79. doi: 10.1002/em.20571. Review.

7.

Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes.

Hamanaka RB, Chandel NS.

Trends Biochem Sci. 2010 Sep;35(9):505-13. doi: 10.1016/j.tibs.2010.04.002. Epub 2010 Apr 27. Review.

8.

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.

Weinberg F, Hamanaka R, Wheaton WW, Weinberg S, Joseph J, Lopez M, Kalyanaraman B, Mutlu GM, Budinger GR, Chandel NS.

Proc Natl Acad Sci U S A. 2010 May 11;107(19):8788-93. doi: 10.1073/pnas.1003428107. Epub 2010 Apr 26.

9.

Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis.

Chae WJ, Gibson TF, Zelterman D, Hao L, Henegariu O, Bothwell AL.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5540-4. doi: 10.1073/pnas.0912675107. Epub 2010 Mar 8.

10.

Heteroplasmic mitochondrial DNA mutations in normal and tumour cells.

He Y, Wu J, Dressman DC, Iacobuzio-Donahue C, Markowitz SD, Velculescu VE, Diaz LA Jr, Kinzler KW, Vogelstein B, Papadopoulos N.

Nature. 2010 Mar 25;464(7288):610-4. doi: 10.1038/nature08802. Epub 2010 Mar 3.

11.

Genomic instability--an evolving hallmark of cancer.

Negrini S, Gorgoulis VG, Halazonetis TD.

Nat Rev Mol Cell Biol. 2010 Mar;11(3):220-8. doi: 10.1038/nrm2858. Review.

PMID:
20177397
12.

Mitochondrial reactive oxygen species regulate hypoxic signaling.

Hamanaka RB, Chandel NS.

Curr Opin Cell Biol. 2009 Dec;21(6):894-9. doi: 10.1016/j.ceb.2009.08.005. Epub 2009 Sep 24. Review.

13.

Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging.

Dai DF, Santana LF, Vermulst M, Tomazela DM, Emond MJ, MacCoss MJ, Gollahon K, Martin GM, Loeb LA, Ladiges WC, Rabinovitch PS.

Circulation. 2009 Jun 2;119(21):2789-97. doi: 10.1161/CIRCULATIONAHA.108.822403. Epub 2009 May 18.

14.

Tumor suppressors and cell metabolism: a recipe for cancer growth.

Jones RG, Thompson CB.

Genes Dev. 2009 Mar 1;23(5):537-48. doi: 10.1101/gad.1756509. Review.

15.

Mouse models of oxidative phosphorylation dysfunction and disease.

Vempati UD, Torraco A, Moraes CT.

Methods. 2008 Dec;46(4):241-7. doi: 10.1016/j.ymeth.2008.09.008. Epub 2008 Oct 10.

16.

A prospective study of mitochondrial DNA copy number and risk of non-Hodgkin lymphoma.

Lan Q, Lim U, Liu CS, Weinstein SJ, Chanock S, Bonner MR, Virtamo J, Albanes D, Rothman N.

Blood. 2008 Nov 15;112(10):4247-9. doi: 10.1182/blood-2008-05-157974. Epub 2008 Aug 18.

17.

Tumor cell metabolism: cancer's Achilles' heel.

Kroemer G, Pouyssegur J.

Cancer Cell. 2008 Jun;13(6):472-82. doi: 10.1016/j.ccr.2008.05.005. Review.

18.

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis.

Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H, Nakada K, Honma Y, Hayashi J.

Science. 2008 May 2;320(5876):661-4. doi: 10.1126/science.1156906. Epub 2008 Apr 3.

19.

Mitochondria in cancer cells: what is so special about them?

Gogvadze V, Orrenius S, Zhivotovsky B.

Trends Cell Biol. 2008 Apr;18(4):165-73. doi: 10.1016/j.tcb.2008.01.006. Epub 2008 Mar 4. Review.

PMID:
18296052
20.

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